No.

Titles / Authors /Abstracts

Full Text

No.

1

On the unification of bio -energy with cosmic- energy

Acharya Sennimalai Kalimuthu

2/394, Kanjampatti P.O, Pollachi Via, Tamil Nadu 642003, India

Email: owlskalimuthu@gmail.com

Researcher ID: AAP-4476-2020

Scopus Author ID: 25723330600

ORCID ID: 0000-0001-7978-9013

MR ID 1048338

Abstract: Maxell unified electricity and magnetism; Abdus Salam and Steven Weinberg unified electromagnetic force with nuclear weak interaction force; Einstein unified mass and energy with his formula E = mc2, Einstein combined space and time. Presently physicists are facing great challenges on the unification of Einstein’s general relativity with quantum mechanics. The physical interpretation of energy states that energy is capacity to do work. The conservation law of energy expresses that energy can neither be created nor destroyed. One form of energy can be converter in to another form. In this work, the author attempts to unify bio- energy with cosmic- energy.

[Acharya Sennimalai Kalimuthu. On the unification of bio -energy with cosmic- energy. Life Sci J 2021;18(3):1-3]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 1. doi:10.7537/marslsj180321.01.

Key Words: Human physiology, respiration techniques, bio-energy, cosmic- energy

Full Text

1

2

Protective impact of Luteolin on Scopolamine induced-Amnesia in Wistar rats: an involvement of Acetylcholinesterase, dopamine and lipid peroxidation

Osama F. Mosa1

Department of Public Health Department, Health Sciences College at Leith, Umm Al Qura University, Al-Lieth, Makkah, KSA.

ofmosa@uqu.edu.sa

Abstract: Background: The alteration in cholinergic transmission is one of the hallmarks of amnesia which is frequently observed in Alzheimer’s disease. Aim: The present study is focused to evaluate the possible protective effect of Luteolin on cognitive functions in scopolamine-induced amnesia in rats. Methods: The rats were divided into five groups containing six animals in each group; Group I the control group, Group II received Scopolamine (0.5 mg/ kg), Group III received Donepezil (10 mg/ kg) along with Scopolamine, and Group IV and V animals received Luteolin (10 mg/ kg and 20 mg/ kg) respectively along with Scopolamine. Results: Luteolin administration resulted in enhancement in learning tendency as observed by remarkable prolongation in time to reconnoiter novel objects, intensification in the retention trial, an increase of the time spent in open arms and diminution in level of AchE as well as lipid peroxidation, while up regulation of brain dopamine levels. Conclusion: Luteolin could be regarded as a beneficial agent proved to be effective against experimental induced-amnesia. Though, the molecular mechanism beyond this effect needs to be explored.

[Osama F. Mosa1. Protective impact of Luteolin on Scopolamine induced-Amnesia in Wistar rats: an involvement of Acetylcholinesterase, dopamine and lipid peroxidation. Life Sci J 2021;18(3):4-11]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 2. doi:10.7537/marslsj180321.02.

Keywords: Amnesia, Alzheimer's disease, AChE, Dopamine, Luteolin, Scopolamine

Full Text

2

3

Development of visual acuity in elementary school children by gender difference

Fen-Chi Lin ¹, Shuan-Yu Huang ^2*

¹ Department of Ophthalmology, Kaohsiung Armed Forces General Hospital, Kaohsiung 802, Taiwan, ROC.

² Department of Optometry, Chung Shan Medical University, Taichung 402, Taiwan

syhuang@csmu.edu.tw

Abstract: The visual acuity, diopter, and visual function of the children in the primary school in Taichuang were investigated, the differences in the visual performance between different genders were also discussed. Experimental results showed that the negative refractive errors in equivalent spherical power for the male schoolchildren was more than the female schoolchildren. Although the average power was not up to the myopia level, it may be occurred in the future. For the difference in gender, it was speculated that the different life styles. In this era of electronic products, male students of this age may have a higher percentage of obsessed with In the case of video games or mobile games, and resulted in such differences.

[Fen-Chi Lin, Shuan-Yu Huang. Development of visual acuity in elementary school children by gender difference. Life Sci J 2021;18(3):12-14]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 3. doi:10.7537/marslsj180321.03.

Keywords: visual acuity, diopter, visual function

Full Text

3

4

Validation OSTA Diagnosis of Osteoporosis in menopausal women by DXA

¹Teng Jun Yan; ^1*Zhiping Guo; ²Fengming Su; ³Yanping Wei

¹Luoyang Orthopedic-traumatological Hospital, Henan, China

²Henan Province People's Hospital, Central China Fuwai Hospital, Henan, China

³Henan Province People's Hospital, Henan, China

First author: junyanteng@hotmail.com

*Corresponding author: guozhiping74@hotmail.com

Abstract: The Osteoporosis Self-Assessment Tool for Asians (OSTA) index has been developed to identify osteoporosis for menopausal Asian women. In this study, to validating OSTA, 267 menopausal women who underwent dual energy X-ray absorption method (DXA) examinations from January 2019 to October 2020 in the towns and urban areas of Zhengzhou city were recruited as the subjects. Via the DXA, the bone mineral density of lumbar vertebrae can be calculated through related formulas. The OSTA index can be validated via DXA in the diagnosis of osteoporosis in primary menopausal women. The T value and OSTA index of the <60-year-old group were greater than those of the 60-75-year-old group and the >75-year-old group (P<0.05); the T value and the OSTA index of the 60-75-year-old group were greater than those of the >75-year-old group (P<0.05). 267 cases of menopausal women showed 152 cases of osteoporosis by DXA, including 82 cases of lumbar osteoporosis and 70 cases of hip osteoporosis. The OSTA high-risk index in lumbar and hip osteoporosis was recognized 67.07% and 68.57%, respectively. The OSTA risk index was recognized 26.25% and 28.57%, and OSTA low-risk index was recognized 7.32%, 2.86% respectively. The sensitivity and specificity of OSTA for the diagnosis of osteoporosis in menopausal women were 83.55% and 79.13%, respectively. The validity of OSTA consistency with the diagnosis of DXA showed that the Kappa value was 0.626. The sensitivity of OSTA to the diagnosis of osteoporosis in menopausal women with lumbar spine osteoporosis and hip osteoporosis was 80.00% and 75.61%, and the specificity was 71.07% and 78.38%, respectively. The Kappa value was consistent with the diagnosis of DXA. They are 0.426 and 0.506 respectively. OSTA can thus be valued by DXA in the diagnosis of osteoporosis in primary menopausal women. The diagnostic efficiency of hip osteoporosis via the OSTA is better than that of lumbar osteoporosis. It is suggested that OSTA should be able to diagnose osteoporosis in primary menopausal women.

[Teng Jun Yan; Zhiping Guo; Fengming Su; Yanping Wei. Validation OSTA Diagnosis of Osteoporosis in menopausal women by DXA. Life Sci J 2021;18(3):15-20]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 4. doi:10.7537/marslsj180321.04.

Key words: Osteoporosis; Menopausal women; OSTA; Dual-energy X-ray absorptiometry

Full Text

4

5

Women Versus Patriarchal Society in Laksmi Kannan’s ‘She’

Anuradha Pawar and Varsha Vast

Teerthanker Mahveer University, Moradabad

Abstract: In this paper we have attempted to reflect the contradiction basically between the inner- self of a women of conventional society and the outer seemingly glamour of her life style. The rigid society shatters her dreams, killing her vision gradually. The surliness of society destroys her capacity to think, her power of estimation and the ability to fulfill unuttered distress and she begins to think alone with the rhythm of the conventional society.

[Anuradha Pawar and Varsha Vast. Women Versus Patriarchal Society in Laksmi Kannan’s ‘She’. Life Sci J 2021;18(3):21-22]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 5. doi:10.7537/marslsj180321.05.

Keyword: Patriarchal Society, feminism

Full Text

5

6

The variation of serum Cystatin C and urinary microalbumin in Neonatal asphyxia

Dai Yiheng¹, Gao Pingming¹, Yang Hui¹, Liu Weidong¹

1Neonatal Department, South Medical University Affiliated Maternal & Child Health Hospital of Foshan, Foshan, Guangdong 528000, China.

 gzgjyxby@163.com

Abstract: Objectives: To explore the detection of Serum cystatin C (Cys C) and urinary microalbumin (UMA) in diagnosing renal impairment of early neonatal asphyxia. Methods: We had 120 cases of full-term neonates who experience asphyxia from our hospital between June 2009 and December 2012, then they were divided into two arms, mild asphyxia and severe asphyxia group, by the admission sequence. 60 cases of health full-term neonates during the same period were as the control group. After 24h birth, we got an approximate blood sample varies from around 2 to 3ml in each neonate among three arms. Automatic biochemistry analyzer made in Hitachi was used to test for renal function, Latex enhance nephelometry immune assay was for serum Cys C, within two days old neonate, we collected 2ml urine and UMA were measured by immunoturbidimetric method. Results: The serum Cys C and UMA of asphyxia groups, Cys C (mg/L)：(1.74±0.21)、(1.510±0.21) UMA (rag/L)：(22.1±5.3)、(14.1±3.2), were higher than the control group, Cys C (mg/L)：(1.201±0.23) UMA (rag/L)：(10.1±3.2), the P value was under 0.05. Between asphyxia groups, severe asphyxia group was higher, and the difference was statistically significant. The abnormal rates of serum Cys C single test, UMA single test and combination of both were 60%、62.5%、90% respectively. Conclusion: Serum cystatin C (Cys C) and urinary microalbumin (UMA) can be used to diagnose renal impairment of early neonatal asphyxia. The combination of two technics is better than single one.

[Dai Yiheng, Gao Pingming, Yang Hui, Liu Weidong. The variation of serum Cystatin C and urinary microalbumin in Neonatal asphyxia. Life Sci J 2021;18(3):23-25]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 6. doi:10.7537/marslsj180321.06.

Keyword: Serum cystatin C; urinary microalbumin; asphyxia; renal impairment

Full Text

6

7

The Health-Related Quality Of Life in Patients with Goiter

Ardashir Afrasiabifar ¹, Azar Rahimi ^2,*, Shaysteh Salehi ²

^{. 1} Department of Nursing, Yasuj University of Medical Sciences, Yasuj, IR Iran

Email: Afrasiabifar.ardashir@yums.ac.ir

²Department of Nursing, Azad University of Khorasgan, Khorasgan, IR Iran

*Email: azar.rahimi13@yahoo.com

Abstract: Now a day the iodine deficiency is the beyond of the thyroid gland enlargement and it may as a major nutritional problem affect quality of life. This study was conducted to evaluate the health-related quality of life (HRQOL) in patients with goiter. This study is a cross sectional study in which 70 patients with goiter were referred to the health centers affiliated with Yasuj University of Medical Science were participated during 2012. Iranian version of SF36 questionnaire was used to collect data and its validity and reliability was approved by preceding studies. The collected data were analyzed by SPSS software under Windows, through descriptive and inferential statistics such as chi-square and t-test with α=0.05. The results showed that the mean score of HRQOL in patients with goiter is 45.2 ± 15/8. Average scores on the eight dimensions of HRQOL except bodily pain and physical function were less than 50. A significant correlation was found between age and physical functioning domain (p=0.006), however, a significant relationship was not found with other areas. Also a significant relationship was found between gender, education level, marital status and income with some domains of HRQOL (p<0.05). According to the mean scores for the eight dimensions of health-related quality of life, the majority of patients with goiter had not satisfactory level of HRQOL.

[Afrasiabifar A, Rahimi A, Salehi Sh. The Health-Related Quality Of Life in Patients with Goiter. Life Sci J 2021;18(3):26-31]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 7. doi:10.7537/marslsj180321.07.

Keywords: Goiter; Iodine Deficiency; Health-related quality of life

Full Text

7

8

A Framework for Formative Assessment within Interactive Video Lectures and its Relation to Reading Comprehension Skills

Ali Hassan Najmi

Department of Educational Technology, Faculty of Educational Graduate Studies, King Abdulaziz University

ahnajmi@kau.edu.sa

Abstract: The current research aimed at designing a framework for formative assessment within interactive video lectures (IVLs) and examine its effect on graduate students reading comprehension skills in English language. A formative assessment framework within IVLs was designed. It has three main components: introduction, watching the IVLs & formative and summative assessment. To examine the effectiveness of the proposed framework, a quasi-experimental approach was used. The proposed framework was applied on a sample of six graduate students representing the first experimental research group. The second experimental research group was also made up of six graduate students who studied using sharable video lectures. The research instrument consisted of a reading comprehension test to examine graduate students’ reading comprehension in terms of overall reading comprehension and the reading comprehension in the literal, interpretive, critical and creative levels. The Non-parametric Mann-Whitney Test was used. The results showed that the proposed framework for formative assessment within IVLs was effective in enhancing graduate students’ overall reading comprehension skills and the reading comprehension in the literal, interpretive, critical and creative levels.

[Ali Hassan Najmi A Framework for Formative Assessment within Interactive Video Lectures and its Relation to Reading Comprehension Skills Life Sci J 2021;18(3):32-41]. ISSN 1097-8135 (print); ISSN 2372-613X (online). http://www.lifesciencesite.com 8. doi:10.7537/marslsj180321.08.

Keywords: Interactive video lectures, formative assessment, reading comprehension skills

Full Text

8

9

Development and quality characterization of cream cottage cheese spread fortified with extra virgin olive oil (Oleaeuropaea L.) based on consumer preferences

Ayesha Khaliq, Hafsa Zahid, Qura-tul-Ain, Sadia Ansar, Ammara Zeeshan, Mahnoor Yaqub, Sonia Rabani, Qamar Sajjad

National Institute of Food Science & Technology, University of Agriculture, Faisalabad, Pakistan

Email: Qamarsajjaduaf@gmail.com

Abstract: Cheese considered as a well-known dairy related product which is manufactured in many varieties according to its texture and flavors. Cream cottage cheese is formed by coagulation of casein and having high protein contents. Due to increase awareness of modern consumers’ fortification of dairy foods including fresh cheese are in demand. Extra virgin olive oil attained by olive fruit is used for this purpose due to the presence of minerals, fatty acids and polyphenols. Required materials were procured from local market and cream cottage cheese was coagulated with lemon juice as it is a high source of citric acid under controlled conditions by short set method and enriched with three different concentration of extra virgin olive oil (2% 4% and 6%). Proximate analysis (moisture, protein, fat contents, ash, total solids, solid not fat) physicochemical analysis, sensory analysis and rheological analysis was performed. Physiochemical analysis showed that as the EVOO concentration in cheese was increased it shows non-significant results on pH, moisture, fat, proteins, total solids, total nitrogen while in case of phenolic compounds, and free fatty acids are significantly affected by quantity of EVOO. Rheological analysis exposed that quantity EVOO had a significant effect on the texture of curd.  Flavor, body and texture, overall acceptance are significantly affected days and concentration. Sample with minimum EVOO concentration show more significant results and overall acceptability as compared to other treated samples. This study was done in order to access influence of three various quantities of EVOO on different properties of cream cottage cheese and to evaluate consumer preference.[Ayesha Khaliq, Hafsa Zahid, Qura-tul-Ain, Sadia Ansar, Ammara Zeeshan, Mahnoor Yaqub, Sonia Rabani, Qamar Sajjad. Development and quality characterization of cream cottage cheese spread fortified with extra virgin olive oil (Oleaeuropaea L.) based on consumer preferences. Life Sci J 2021;18(3):42-48]. ISSN 1097-8135 (print); ISSN 2372-613X (online). http://www.lifesciencesite.com. 9. doi:10.7537/marslsj180321.09.

Key words: Extra virgin olive oil, Cream cottage cheese, EVOO fortification. Quality attributes consumer preference.

Full Text

9

10

Hydroxychloroquine: The Second Revolution in Medical Science After Penicillin

Ning Ye

Address: Flushing, Queens, New York, USA

Corresponding to: Ning Ye

Email: yeningusa@gmail.com

Abstract: This manuscript was written under the urgent pressure of being motivated in saving lives of Covid-19 epidemics which has claimed more than 500,000 American lives since February 2020, most likely due to virtual absence of correct therapy. The author is not a professional virologist/epidemiologist. With family background of Chinese traditional herbal medicine, this author had extensive learning experience interacting in appendices nature with the world’s improved ways to produce and concentrate on the drug and prove its antiviral effects following topnotch scientists in medical science mostly in the NIH, the world’s most prestigious headquarter compound representing the most cutting-edge life science development.

[Ning Ye. Hydroxychloroquine: The Second Revolution in Medical Science After Penicillin. Life Sci J 2021;18(3):49-53]. ISSN 1097-8135 (print); ISSN 2372-613X (online). http://www.lifesciencesite.com 10. doi:10.7537/marslsj180321.10.

Keywords: live; Covid-19; epidemics; therapy; virology; epidemiology; Chinese traditional herbal medicine; drug; NIH; science

Full Text

10

11

Morphology variation among eleven local populations of the endemic Myotis davidii in China

Yuyan You¹, Jiangfeng Du², Lei Wang³, Tinglei Jiang³

^1. Beijing Zoo, Beijing, 100044, China

^2. China National Offshore Oil Corporation Research Center, Beijing, 100027, China

^3.College of Urban and Environmental Science, Northeast Normal University, Changchun, 130024, China

 youyy351@163.com 

Abstract: The David’s myotis (Myotis davidii) is a endemic species of China. In our research, we investigated the relationships between the genetic, environmental, geographic variations and the external variations. Mantel test indicated influencing the external variable by genetic distance, geographic distance and environmental Euclidean distance. When we used stepwise linear regression to analysis the influencing extent of each environmental factor on the phenotypic variation, the results indicated that the temperature was the most important factor influencing phenotypic variation among ten environmental variables. We also reconstituted the phylogenetic tree based on the mitochondrial DNA HIV sequence, external or combined data of eleven local Myotis davidii populations, respectively, in order to infer the biogeography distribution patterns of external and genetic variables. ML tree, BI tree and phenotypic minimum spanning tree were all divergent into three lineages (region IF, IIA and IIC in lineage A; region IVB, IVD and IVE in lineage B; region IID in lineage C). And the external and genetic variation patterns paralleled with unique Chinese topographic and physiogeographic features in general. However, individuals from southeast mid-low elevation mountain areas (IID) showed a difference compared to other regions and might be a transition area connecting the eastern plain and western plateau. Our results highlight the importance of adaptive divergence for geographical patterns. And the external variables along the genetic divergence, environmental and geographic gradient, evolutionary branching can occur much more easily, which increased availability of phylogeographical and ecological data should facilitate further understanding of population divergence drivers at broad scales.

[Yuyan You, Jiangfeng Du, Lei Wang, Tinglei Jiang. Morphology variation among eleven local populations of the endemic Myotis davidii in China. Life Sci J 2021;18(3):54-63]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 11. doi:10.7537/marslsj180321.11.

Keywords: D-loop; Topography; Geographical variation; Environmental characteristic; External variables

Full Text

11

12

Role of Autophagy in Rat Acute Spinal Cord Injury Induced by Rapamycin

Haicheng Yan^1,2#, Changwu Dou^2#, Wei Wang³, Fuming Tian^1,2, Youle Su^1,2, Songtao Qi^1*

1. Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.

2. Department of Neurosurgery, The Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Medical University, Hohhot,010050, China

3. The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.

^*Corresponding author at: Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.

Email address: nmgyhc1981@126.com

^#These authors contribute equally to this article (co-first author).

Abstract: Several clinical predictors of neurological outcome after traumatic spinal cord injury (SCI) have been identified, including severity of injury, level of injury, and a zone of partial preservation. The process of autophagy plays a role in protecting cells from damage. in this study,we explored the effects of rapamycin-induced autophagy on apoptosis in a rat model of acute spinal cord injury (SCI), and explored the effect of rapamycin on apoptosis in primary spinal cord cell culture. Our study found that The expression of the apoptosis-related protein caspase-3 did not significantly increase until 21 days following injury, while increases in LC3II and LC3I began 10 days after injury, but then declined. TUNEL staining and electron microscopy confirmed that following injury autophagy occurred before apoptosis, but by 14 days after the injury, the level of autophagy had decreased significantly while the level of apoptosis showed a continued increase. Following treatment with rapamycin, apoptosis was significantly higher than in the vehicle control group, but significantly lower than in the sham-operated group, showing a protective effect of rapamycin. Gale scale grades in rats treated with rapamycin were significantly higher compared with the vehicle control group, suggesting a functional effect of rapamycin-induced inhibition of apoptosis. Our results indicate that rapamycin significantly improved the prognosis of acute SCI in rats by inhibiting cell apoptosis.

[Haicheng Yan, Changwu Dou, Wei Wang, Fuming Tian, Youle Su, Songtao Qi. Role of Autophagy in Rat Acute Spinal Cord Injury Induced by Rapamycin. Life Sci J 2021;18(3):64-71]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 12. doi:10.7537/marslsj180321.12

【Key words】Autophagy , Rapamycin,spinal cord injury

Full Text

12

13

Estimation of genetic components for various physiological traits in Zea mays L under water deficit conditions

Nazar Hussain Khan^1*, Muhammad Ahsan¹, Muhammad Saleem¹ and Asghar Ali²

1.       Department of Plant Breeding and Genetics, University of Agriculture Faisalabad, Pakistan

2.       Department of Agronomy, University of Agriculture Faisalabad, Pakistan

nazarpbg@gmail.com

Abstract: Drought is a solemn environmental factor that causes great loss of yield in maize crop. Maize is highly sensitive to drought. There is need to develop drought tolerance maize genotypes to fulfill demand of feed for livestock and food for human. For this propose prescribed study was conducted to estimate genetic components for various physiological traits under normal and water tress conditions in the research area of the Department of Plant Breeding and Genetics, University of Agriculture Faisalabad, Pakistan. It was concluded that P₁ (WFTMS) parent performed better under drought conditions for stomata frequency, stomata conductance, stomata size, cell membrane thermo stability, leaf water potential and excised leaf water loss while BC₂ for stomata conductance, F₁ for stomata size, F₂ leaf water potential and BC₁ for leaf temperature. Positive [h] dominance effects were recorded for cell membrane thermo stability, stomata afrequency and leaf water potential while [d] additive effects for leaf water potential under normal conditions. It was reported that [i] additive × additive interaction were found for cell membrane thermo stability, stomata frequency and excised leaf water loss while negative for leaf water potential under normal conditions while under drought for cell membrane thermo stability, stomata frequency, stomata conductance and excised leaf water loss. It was suggested that the traits showed [d] additive and [i] additive × additive interaction may be used to fix the increase in the expression of traits in next generations and selection for the development of synthetic varieties for drought resistance may be helpful. The [h] dominance effects showed that the traits may be used for the development of hybrid. On the basis of genetic effects it was concluded that stomata frequency, stomata size, cell membrane thermo stability, leaf water potential and excised leaf water loss may be helpful for the development of higher grain yield maize genotypes under drought conditions.

[Khan NH, Ahsan M, Saleem, M and Ali A. Estimation of genetic components for various physiological traits in Zea mays L under water deficit conditions Life Sci J 2021;18(3):72-80] (ISSN:1097-8135). http://www.lifesciencesite.com. 13. doi:10.7537/marslsj180321.13

Key words: generation mean analysis, Zea mays, drought, additive, dominance

Full Text

13