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Comparative Study Of Swim Bladder In Some Siluroids Fishes

Chanda Jha and Abhay Kumar

P.G. Department Of Zoology, T.M.B. University, Bhagalpur 812007

Email: *chandajha.jha@gmail.com ** abhayecologist@gmail.com

Contact: 6205510040, 8292357523

Abstract: The present study focuses on the structural differences of swim bladder between some fishes of order Siluriformes. Four fishes from the family Schilbeidae two from family Bagridae, two from siluridae and one from Sisoridae were taken up observation. A collective information of the swim bladder and their differences between closely related families would be useful for taxonomic correlation and position in further studies. Remarkable differences of the swim bladder were found between the same families described here, though there habitat and feeding behaviour were same. Although the swim bladder was almost similar in Ompok bimaculatus and Wallago attu, in Mystus cavasius it bears two horn like projections on its anterior corners and in Rita rita of the same family Bagaridae two tube like outgrowths or diverticulum run downwards from the posterior corners of the swim bladder. The swim bladder species of the family Sisoridae Laguvia ribeiroi ribeiroi was bilobed, situated in two lateral cavities. The four species of the family schilbeidae showed much differences in the structure of organ concerned. It was interesting to note that in some species the swim bladder was greatly reduced whereas in Pseudeutropius aetherinoids it was developed and resembled the swim bladder of Ompok and although they were kept in different families.

[Chanda Jha and Abhay Kumar. Comparative Study Of Swim Bladder In Some Siluroids Fishes. Life Sci J 2020;17(12):1-19]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 1. doi:10.7537/marslsj171220.01.

Key Words: Diverticulum, Habitat, Swim Bladder

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Cloning and CRISPR/Cas9-mediated targeted mutagenesis of NtTRE in Nicotiana tabacum

Chungui Tang¹, Zengguang Zhai ¹, Yuefeng Zhong², Pengfeng Chen², Feng Zhou², Dewu Zeng², Shipeng Xiang¹, Kunfeng Song³, Hongxiang Guo³, Weihuan Jin^3*, Weiqun Liu^3*

¹Changsha Municipal Tobacco Company, Changsha 410007, China

²Liuyang Branch of Changsha Tobacco Company, Liuyang 410300, Hunan, China

³College of Life Science, Henan Agricultural University, Zhengzhou, 450002, China

^*Corresponding author: whjin@henau.edu.cn and liuweiqun2004@126.com

Abstract: In order to study the function of trehalase in tobacco, the trehalase (EC 3.2.1.28) gene was cloned from Tobacco K326 (Nicotiana tabacum). CRISPR/Cas9 genome editing technology was applied to create the mutagenesis in NtTRE. Two targets were selected as the editing sites in the first extron of NtTRE. The pORE-CRISPR/Cas9 vector was constructed to edit target sequence. As a result, 15 transgene lines were obtained. Of them, there were 3 lines to be knocked out successfully. The first mutant is A inverted T on 285 site. The second mutant is A inverted T on 293 site, and the third were two mutation site, A inverted T on 285 and A inverted G on 295 site. All of these three mutations can cause NtTRE to be replaced by another protein. In this study, we produced mutants materials for further researching trehalose and NtTRE functions in tobacco.

[Chungui Tang, Zengguang Zhai, Yuefeng Zhong, Pengfeng Chen, Feng Zhou, Dewu Zeng, Shipeng Xiang, Kunfeng Song, Hongxiang Guo, Weihuan Jin, Weiqun Liu. Cloning and CRISPR/Cas9-mediated targeted mutagenesis of NtTRE in Nicotiana tabacum. Life Sci J 2020;17(12):20-23]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 2. doi:10.7537/marslsj171220.02.

Keywords: trehalase; trehalose; CRISPR/Cas9; Nicotiana tabacum

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Pharmacologic vitreolysis of floaters by 2-month pineapple juice supplement- an animal study

Mei Fang ¹, Chi-Ting Horng ^2,3*

¹ Department of Pharmacy, Kaohsiung Armed Forces General Hospital, Kaohsiung, 802, Taiwan, ROC.

² Department of Pharmacy, Tajen University, Pingtung, Taiwan, ROC.

³ Department of Ophthalmology, Kaohsiung Armed Forces General Hospital, Kaohsiung 802, Taiwan, ROC.

h56041@gamil.com

Abstract: Introduction: This is a new method of pharmacologic vitreolysis from the nature fruit supplement that was a developed technique in the world. Methods: Our study was completed between April 2020 and June 2020. A total of 36 SD rats with 36 eyes were enrolled in our studies and received ocular retinal check- up. Every SD rat was fed with various doses of pineapple according to our protocol. Experiment 1, 12 mice were classified into Group 1 (group with one symptomatic vitreous opacity (SVO)) and Group 2 (group with multiple SVOs) which was all fed with 20 mg pineapple mixed with diluted water (10 CC) every day. In Experiment 2, other 24 eyes from SD rats with SVOs were all randomly divided into four groups including the placebo group; low pineapple juice group (LPG) (10 mg/day); middle pineapple group (MPG) (20 mg/day); and high pineapple group (HPG) (40 mg/day), respectively. At final, we analyzed the change in SVOs in all experiments. Besides, we examined the pathology of kidneys and livers from sacrificed rats after 2 months. Results: In experiment 1, 6 SD rats with one SVO decreased to 3 subjects (P < 0.05) and the rate of success was 50.0 % (3/6) after 2 months feeding. The 6 cases with multiple SVOs decreased to 2 rats (27.5%) after 2-month therapy (P < 0.05). The disappear rate was 72.5% in the multiple-SVOs group. In experiment 2 (N=24), the final disappear rate in the 4 groups with placebo, LPG, MPG, and HPG were 100%, 33.3%, 50% and 66.3%, respectively. In other words, the disappear rate was 33.3%, 50% and 66.3% of SVOs in LGP, MGP, and HGP after 2 months of the pineapple juice supplements ( P < 0.05). Hence, the results showed that the unified effects treating SVOs in a dose-dependent manner; the higher the dose, the greater the SVO reduction. Besides, there were no abnormal finding in kidneys and livers in all SD rats after feeding with 2 months. Furthermore we suggested that the mechanisms of dissolving and absorbing SVOs may be due to the proteinase and hydrolysis and antioxidant activities that may clear the compromised vitreous opacity and scavenge the free radicals in the vitreous. Conclusion: We demonstrated that pineapple intake may excise SVOs and eliminate intraocular hemorrhage by cleaving the collagen fibrils and the cellular debris that may induce any types of ocular floaters.

[Mei Fang, Chi-Ting Horng. Pharmacologic vitreolysis of floaters by 2-month pineapple juice supplement- an animal study. Life Sci J 2020;17(12):24-32]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 3. doi:10.7537/marslsj171220.03.

Keywords: symptomatic vitreous opacity; ocular floater; bromelain; pineapple.

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Study of Pulmonary Hypertension in Chronic Kidney Disease patients in Sohag University Hospital

Noher Mohamad Abass, Nayel Abd El-hameed Zaky, Ahmed Mohamed Boghdady, Lotfy Hamed Abo-Dahab.

Department of Medicine, Faculty of Medicine, Sohag University, Sohag, Egypt

Abstract: Introduction: Early diagnosis and early treatment of PH might improve the long-term outcomes. Therefore, it is crucial to investigate the epidemiology of PH before patients with CKD progress to ESRD. Patients and Methods: A cross sectional study was conducted on 228 patients with CKD in Sohag University Hospital. They were divided into two groups: group 1, Included 104 patients with CKD on conservative management (28 patients stage 3, 36 patients stage 4, 40 patients stage 5 NDD-CKD) who attended to out-patient clinic and admitted patients in internal medicine department, group II involved 124 patients with CKD who were maintained on long term regular hemodialysis therapy three times per week. Every patient in both groups underwent a complete two-dimensional and doppler echocardiography study. Tricuspid regurgitation velocity (TRV) was used to determine RV systolic pressure, which is considered equal to systolic pulmonary arterial pressure (SPAP) and compared between both groups. Results of the study: The current study showed that PH (SPAP> 35 mmHg) was demonstrated in 24% among 104 patients with CKD stages 3–5 non dialysis dependent with a mean systolic PAP of (41.1± 3.1 mmHg) and (49%) among 124 patients receiving long-term hemodialysis with a mean systolic PAP of (43.1± 7.2 mmHg) and this difference was statistically significant (with a p. value of < 0.001). Conclusion: PH is a common finding in CKD patients; the prevalence was highest among patients with ESRD receiving long-term hemodialysis than those on conservative management. Early detection of PH is important in order to avoid the serious consequences of the disease.

[Noher Mohamad Abass, Nayel Abd El-hameed Zaky, Ahmed Mohamed Boghdady, Lotfy Hamed Abo-Dahab. Study of Pulmonary Hypertension in Chronic Kidney Disease patients in Sohag University Hospital. Life Sci J 2020;17(12):33-40]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 4. doi:10.7537/marslsj171220.04.

Keywords: Study; Pulmonary; Hypertension; Chronic Kidney Disease; patient; Hospital

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A two paramedian vaginalincisions versus the standard longitudinal incision of trans-obturator tape procedure for the management of stress urinary incontinence: A randomized controlled trial

Mohamed A. Gamal¹; Ahmed M. Higazy²; Ahmed Farouk¹; Ahmed A. El Shorbagy¹; Ahmed M. Tawfeek³; Ahmed I. Radwan¹

¹Consultant of Urology/Lecturer, Ain Shams University Hospitals, Cairo, Egypt

²Assistant Lecturer of Urology/Specialist, Ain Shams University Hospitals, Cairo, Egypt

³Ain Shams University Hospitals, Cairo, Egypt.

E-mail: dr.mohgamal@gmail.com, Ahmedmaherhigazy@gmail.com, dr_farouk77@yahoo.com, a.amr.shorbagy@gmail.com, Drahmedtawfeek@med.asu.edu.eg, Ahmedradwan67@gmail.com

Abstract: Purpose: To evaluate the rate of success and the migration of tape in a modern surgical approach using 2 paramedian vaginal incisions compared to the standard longitudinal incision of the trans-obturator tape procedure. Methods: A randomized clinical trial was performed including 100 SUI patients; they were divided into 2 groups representing the two paramedian vaginal incisions versus the longitudinal vaginal incision. The clinical outcomes and tape location were assessed at 3,6 and 12 months following operation. Results: Forty-eight patients in group 1 underwent the classical surgical technique while the two paramedian incisions reflecting group 2 were made in 42 patients. The cure rate in group 1 was 70.8%, while only 6% of the cases showed no improvement compared to 78.6% cure rate in group 2, and 4% of cases showed no improvement. The incidence of tape migration was 52.1% in group 1 while no migration was noted in group 2. Failure to complete cure was associated with tape migration in 6 cases of group 1 representing 32 % of the total tape migration, these results were significant to correlate migration with failure to complete cure, also De novo urgency was seen to be associated with proximal tape migration. Conclusion: The 2 paramedian vaginal incisions provide greater stabilization and less tape migration, that enhances the rate of success. Trial registration number: the trial was registered at clinicaltial.gov with trial registration number: NCT04571346, date: 1^st of October 2020, retrospectively registered.

[Mohamed A. Gamal; Ahmed M. Higazy; Ahmed Farouk; Ahmed A. El Shorbagy; Ahmed M. Tawfeek; Ahmed I. Radwan. A two paramedian vaginalincisions versus the standard longitudinal incision of trans-obturator tape procedure for the management of stress urinary incontinence: A randomized controlled trial. Life Sci J 2020;17(12):41-47]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 5. doi:10.7537/marslsj171220.05.

Keywords: Stress urinary incontinence, trans-obturator tape, tape migration, sling procedure, voiding dysfunction

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Species Composition and Distribution of Earthworms in Hue City, Vietnam and Its Vicinity

Nguyen Van Thuan, Nguyen Thi Thuy, Tran Van Giang, Tran Quoc Dung ^⃰

Faculty of Biology, University of Education, Hue University, 34 Le Loi Street, Hue City, Thua Thien Hue Province, Vietnam

tranquocdung@hueuni.edu.vn

Abstract: Background: Earthworms are the largest members of the order Opisthopora, the class Oligochaeta of phylum Annelida. They are distributed worldwide in different habitat and beneficial components of soil fauna since they dominate the invertebrate biomass in the soil. Earthworms as an alternative protein source in poultry, cattle and fish farming. Many earthworm species have been utilized as an important source of food for cattle and poultry. Thousands of different earthworm species have been identified worldwide with reports on diversity and distribution of earthworms in various parts of the world. Aim: This research was carried out to determine species composition and distribution of earthworms in the pig farming areas in Hue city, Vietnam and its vicinity. Material and methods: Earthworms were collected according to the method described by Ghilliarov (1975). The collected earthworms were identified using the external morphology key of Bai (1983) and Blakemore (2002). Outcomes were expressed in terms of biomass (fresh weight in g/m²) and density (ind/m²). Results: Thirteen earthworm spe­cies belonging to two families Megascolecidae and Glossoscolecidae were found from study areas during our study period from December 2018 to April 2019. P. elongata was found in all the ten study sites, and being distributed in all the strata with the earthworm density, and the fresh weight biomass were highest. Conclusion: The present study will provide new insight on earthworms in the pig farming areas of Hue city, Vietnam and its vicinity and will be valuable resources such as species composition, distribution, diversity for future basic and applied earthworm research, particularly in Thua Thien Hue, Vietnam.

[Nguyen Van Thuan, Nguyen Thi Thuy, Tran Van Giang, Tran Quoc Dung. Species Composition and Distribution of Earthworms in Hue City, Vietnam and Its Vicinity. Life Sci J 2020;17(12):48-54]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 6. doi:10.7537/marslsj171220.06.

Keywords: Earthworms, species composition, distribution, Hue city, Vietnam

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Length–Weight Relationships of Twelve Fishes from the Padma River near Rajshahi City, Bangladesh

M. Golam. Mortuza^{1, 2*}, Hamed A. El-Serehy¹ and Fahad A. Al-Misned¹

¹Department of Zoology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia

²Department of Zoology, Faculty of Life and Earth Science, Rajshahi University, Rajshahi 6205, Bangladesh

E-mail: mmortuza@ksu.edu.sa

Abstract: The present observations are significant for conservation and management of freshwater economic important fishes of the Padma River. The objective was to evaluate the length-weight relationships (LWRs) of freshwater fish species, which serves as a baseline for comparison to other relatively altered tropical Bangladeshi rivers. The length–weight relationships (LWRs) were studied of 12 species belonging four classes, seven families and 11 genera (Gagata youssoufi, Cirrhinus reba, Clupisoma garua, Ompok bimaculatus, Pangasius pangsius, Securicula gora, Ailia coila, Chanda nama, Parambassis ranga, Botia lohachata, Rhinomugil corsula and Labeo boga) are captured from the River Padma near Rajshahi City, Bangladesh. The length (L) - weight (W) relationships were estimated using the logarithmic form of the equation W = aL^b. The exponent b varied from 2.813 to 3.173. This study describes the length–weight relationships (LWRs) of 12 species of fishes from the Padma River, near Rajshahi city, Bangladesh.

[Mortuza MG, El-Serehy HA, Al-Misned FA. Length–Weight Relationships of Twelve Fishes from the Padma River near Rajshahi City, Bangladesh. Life Sci J 2020;17(12):55-58]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 7. doi:10.7537/marslsj171220.07.

Key Word: Length-weight relationship, allometric growth, isometric growth

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A Multi-Stage Clustering Approach for Cerebrospinal Fluid Image Segmentation

Afnizanfaizal Abdullah^1,2*, Akihiro Hirayama³, Satoshi Yatsushiro⁴, Mitsunori Matsumae³, Kagayaki Kuroda^2,4

^1. Artificial Intelligence and Bioinformatics Group (AIBIG), Faculty of Computer Science and Information Systems, Universiti Teknologi Malaysia, 81310 UTM, Johor, Malaysia

^2. Course of Information Science and Technology, Graduate School of General Science and Technology, Tokai University, 4-1-1 Kitakaname, Hiratsuka, 259-1292, Japan

^3. Department of Neurosurgery, School of Medicine, Tokai University, Isehara, Kanagawa, 259-1188, Japan

^4. Department of Human and Information Sciences, School of Information Science and Technology, Tokai University, 4-1-1 Kitakaname, Hiratsuka, 259-1292, Japan

afnizanfaizal@utm.my

Abstract: Analysis of the cerebrospinal fluid (CSF) flow within brain has become increasingly important to diagnose a number of neurodegenerative disorders. Magnetic resonance imaging (MRI) is utilised to measure the CSF volumetric change in patients. However, the quality of the images is often hampered by partial volume effect, which blurred the boundary between the brain tissues and the CSF. Consequently, the accuracy of CSF analysis is reduced significantly. In this paper, we introduce a new multi-stage clustering approach to overcome this limitation. Firstly, the T1-weigthed images are fused with the corresponding T2-weigthed images. Next, the resulting images are subjected to partial volume estimation using Gaussian mixture model. The model produced by these images is later used as input in a spatial fuzzy clustering algorithm to segment the CSF flow from the brain tissues. Benchmark images obtained from BrainWeb are used to validate the performance of the proposed approach. In addition, we also presented the performance of the proposed method using real MRI images taken from a number of Alzheimer’s disease patients, which evidently showed the effectiveness of the method in quantifying the CSF flow within the brain.

[Abdullah A., Hirayama A., Yatsushiro S., Matsumae M., and Kuroda K. A Multi-Stage Clustering Approach for Cerebrospinal Fluid Image Segmentation. Life Sci J 2020;17(12):59-66]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 8. doi:10.7537/marslsj171220.08.

Keywords: Image segmentation; image fusion, Gaussian mixture model; spatial Fuzzy C-Means

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Potential of Thaumatococcus danielli in Animal Nutrition

Oforibika George Adieboye, Ogoloma Jude Udeme, Ezekiel Tamunodiepriye

Department of Science Laboratory Technology, School of Science and Technology, Port Harcourt Polytechnic Rumuola, P.M.B. 5936, Port Harcourt, Rivers State

oforibikaa@yahoo.com

Abstract: This study investigates the potential effect of Thaumatococcus danielli in animal nutrition. Proximate analysis and phytochemical studies of T. danielli of leaves and roots was carried out. Protein contents were analyzed by (Kjeldhal method), carbohydrate (Anthone method), moisture (Oven method) and lipid (soxhlet extraction). Results revealed that the leaves and roots of estimated protein was [14.88(± 0.18g)/7.00(±0.12g)], carbohydrate [31.25(±0.52g)/18.75(±0.37)], fibre [36.61(±0.18g)/48.98(±0.32)], moisture [5.16(0.26g)/17.27(0.09)], lipid [0.90(±0.02g)/1.80(± 0.06)] and ash [10.60(± 0.19g)/17.27±(0.22g )]. It is apparent from this study that T. danielli is a suitable replacement for cereal grains and therefore must be encouraged if the increasing demand for animal protein must be sustained in Nigeria especially in this period of economic recession.

[Oforibika, G.A., Ogoloma, J. U. and Ezikiel, T. Potential of Thaumatococcus danielli in Animal Nutrition. Life Sci J 2020;17(12):67-70]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 9. doi:10.7537/marslsj171220.09.

Keywords: Thaumatococcus danielli, animal nutrition, economic recession, Nigeria, cereal.

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Addis Ababa University, Selale campus

Assessment Of Indications For Emergency Cesarean Section And Its Outcomes At St. Paul’s Hospital Medical College, Addis Ababa, Ethiopia 2017: (Afour Month Retrospective Cohort Study).

 Bizuneh Ayano¹, Ayana Guto ²

^1. Lecturer at Department of Public health, Selale campus, Addis Ababa University, Fiche Town, Ethiopia

^2. Medical Doctor at ST. Paul’s Hospital Medical College, Addis Ababa City, Ethiopia

 bizunehayano@gmail.com

Abstract: BACKGROUND: Cesarean section (CS) rates and their indications vary all over the World. Audit of indications and factors affecting infant and maternal outcome remain an important activity in rationalizing the use of this major procedure in obstetrics practice. Cesarean section (CS) carries a higher maternal morbidity and mortality compared to vaginal delivery. Objective: To determine the leading indications for ECS and their associated maternal and neonatal outcomes in St. Paul’s Hospital Millennium Medical College (SPHMMC). Methodology: Retrospective facility-based study was used and data was collected by reviewing the log book of patients who underwent CS operations at St. Paul’s Hospital Millennium Medical College (SPHMMC) gynecology obstetric department from 1^st February to 30^th May 2017. The leading indications for Emergency Cesarean Section (ECS) were determined in terms of frequency and percentage. Clinical outcomes of the mothers and the delivered newborns were gauged by morbidity, mortality and survival rates (i.e. within the hospital confinement). Results: A total of 2345, deliveries were conducted, of which 582 deliveries were by cesarean section procedures making the institutional cesarean section rate of 25%. Records of patients who underwent Emergency Cesarean section (ECS) were retrieved and comprised the study population (N=522). Perinatal Asphyxia (PNA) was the most common cause of the neonatal death 6 (42.9%). Dystocia (26.4%) emerged as the leading indication for ECS followed by Non reassurance fetal heart rate pattern (NRFHRP) (18.8%). an association between indications of EC/S, Appearance, Pulse, Grimace, Activity, Respiration (APGAR) scores at 5^th minute and fetal outcome with p value of <0.05 was observed. Conclusions: The institutional cesarean section rate is high (25%), compared to the WHO recommendation. Maternal outcome was favorable with 94.8% of them, smooth post operation course and no maternal death record during hospital confinement. Surgical site wound infection was the most common accounting for 63.0%, among post operation complications that mothers developed. Dystocia (26.4%) emerged as the leading indication for ECS followed by Non reassurance fetal heart rate pattern (NRFHRP) (18.8%), Meconium stained Amniotic fluid (10.7%) and failed induction (5.4%). Neonatal outcome was seen to be better than other similar studies with survival rate of 94.1%. There was an association between indications of Emergency Cesarean Section (ECS), Appearance, Pulse, Grimace, Activity, Respiration (APGAR) scores at 5^th minute and fetal outcome with p value of <0.05.

[Ayano B, Guto A. Addis Ababa University, Selale campus. Life Sci J 2020;17(12):71-86]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 10. doi:10.7537/marslsj171220.10.

Keywords; Cesarean section, Magnitude, indications, factors, pregnancy, outcome, Ethiopia

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Short-term outcome of hepatocellular carcinoma resection in elderly cirrhotic patients

Ashraf Mohammad El-Badry^*, Mohamed Mahmoud Ali

¹Department of Surgery, Sohag University Hospital, Faculty of Medicine, Sohag University, Sohag, Egypt

E-mail : elbadryam@yahoo.com

Abstract: Background: Advanced age and liver cirrhosis predispose to suboptimal regenerative response after partial liver resection. Clinical outcome of hepatocellular carcinoma (HCC) resection in elderly cirrhotics was not adequately addressed in Upper Egypt onco-surgery programs. Methods: Medical records of adult patients who underwent elective liver resection for HCC at Sohag University Hospital (February 2014 – August 2017) were retrospectively analyzed. Elderly patients (≥ 65 years) were compared regarding postoperative hepatic failure, morbidity and mortality with non-elderly matched control group (< 65 years). Results: Twenty-two patients were enrolled, 11 per group. All patients had HCC on top of compensated, hepatitis C-related liver cirrhosis. The elderly group showed significantly worse grades of postoperative complications (p< 0.05), prolonged hospital stays (p< 0.05) and significantly deranged markers of posthepatectomy liver failure, including increased levels of bilirubin and reduced prothrombin concentration (p< 0.05). Postoperative mortality occurred only in the elderly group (2 postoperative deaths following major hepatectomy). Mortality was associated with postoperative day-1 thrombocytopenia <100 ×10⁹/L. Conclusion: Elderly cirrrhotic patients are more vulnerable to worse outcome after major liver resections. To ensure satisfactory results of HCC resection in this category of patients, strict selection criteria should be considered.

[Ashraf Mohammad El-Badry, Mohamed Mahmoud Ali Short-term outcome of hepatocellular carcinoma resection in elderly cirrhotic patients Life Sci J 2020;17(12):87-91]. ISSN 1097-8135 (print); ISSN 2372-613X (online). http://www.lifesciencesite.com  11. doi:10.7537/marslsj171220.11.

Key words: elderly, hepatocellular carcinoma, liver resection, cirrhosis

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