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Laparoscopic MGBP after removal of gastric Band

Mohamed Magdy MD, Sherif Abd ELHalim M.D. MRCS

General Surgery Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt

mmagdy25@hotmail.com

Abstract: Background: Obesity is considered one of the leading causes of death around the world, obesity is considered as one of the most serious public health problem of the 21st century. Obesity can be treated using surgical or non-surgical approaches. During the last 20 years, laparoscopic gastric banding have been one of the most successful approaches of bariatric surgery. However, more than 40% of LAGB procedures have been associated with many side effects and long term complications and failure. In cases of failed LAGB surgery, many surgeons have recommend the conversion to laparoscopic mini gastric bypass. Aim of the work: To study the assess the success of the laparoscopic mini gastric bypass (LMGB) operations as a revisional bariatric procedure after the failure of the gastric binding operations, and to study the beneficial effects of this procedure on the quality of life of the patients. Material and methods: This study was conducted in Ain Shams University Surgery Hospital in Cairo between November 2015 and June 2018. Patients underwent laparoscopic mini gastric bypass operation as a revisional procedure after the failure of LAGB operation. The exclusion criteria was for the patients to have previous bariatric surgery, or other surgery and cases with insufficient necessary data. Results: The mean hospital stay time after the revision was 4.23±3.2 days. There was a statistically significant difference in the BMI of the patients after 6 months. After 6 months of the surgery we found a significant decrease in the number of the diabetic patients. The number of patients with sleep apnea dropped significantly. All of the patients with GERD were cured. Conclusions: We found that the conversion of failed LAGB to LMGB is considered to a safe and easy procedure to perform. Patient satisfaction was high, and recovery time was short. We also reported further significant weight loss and decreased comorbidities after the revision surgery.

[Mohamed Magdy, Sherif Abd ELHalim. Laparoscopic MGBP after removal of gastric Band. Life Sci J 2020;17(1):1-6]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 1. doi:10.7537/marslsj170120.01.

Keywords: Laparoscopic; MGBP; removal; gastric Band

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Early Detection of Invasive Fungal Infections after Liver Transplantation: Single Center Experience

Rasha O Refaie¹*, Yasmine M Massoud², Sahar Mohamed Lotfy³, Mohamed A Rady⁴ Mahmoud S El Bokhary ⁵, Nahed A Makhlouf ⁶

¹Assistant Professor of Internal Medicine – Head of Internal Medicine Department, Helwan University. Liver Transplantation Unit, Wadi El Nile Hospital, Egypt.

²Lecturer of Tropical Medicine, Faculty of Medicine, Ain Shams University, Liver Trasnplant Hepatologist at Ain Shams Center for Organ Transplantation, Cairo, Egypt

³Master of Chemistry and Clinical Pathology, Faculty of Medicine, Ain Shams University. Doctor of Philosophy Degree in Environmental Science. Department of Environmental

⁴Assistant Professor of Hepatobiliary Surgery, Faculty of Medicine, Ain Shams University, Liver Trasnplant Surgeon at Ain Shams Center for Organ Transplantation, Cairo, Egypt.

⁵Prof. of Chest Diseases, and Head of Department of Environmental Medical Sciences. Institute of Environmental Studies & Research. Ain Shams University.

⁶MD, Professor of Tropical Medicine & Gastroenterology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.

Email: rasha.refaie@med.helwan.edu.eg

Abstract: Background: The incidence of invasive fungal infections (IFIs) after solid organ transplantation ranges from 7–42%. Fungal infections after liver transplantation have poor outcome and high mortality rate. The prognosis mainly depends on early treatment for IFIs. Therefore, the diagnosis needs to be prompt depending on the documented risk factors, the duration of operative procedure, the amount of bleeding, the rejection rate and re-transplantation. bAim of work: To determine the incidence of IFIs in liver transplant recipients and to identify various risk factors Material/Methods: This study was performed at the Liver Transplantation Unit, Wadi El Nile Hospital, Egypt during a 2 year period. Fifty consecutive liver transplant recipients were prospectively observed for fungal infections, and the detection of fungal antigen in blood or sterile fluid was done by ELISA. Results: Sixteen patients (32% of the total group) had 19 episodes of fungal infection. Candida was the causative agent in (87.5%) of IFIs and Aspergillus accounted for (31%). Serum creatinine level, dialysis, SBP, MELD and serum bilirubin were significant pre-transplant. risk factors. Operative time, duration of ICU stay, documented bacterial infections were also risk factors. Conclusions: Early detection of fungal infection and prompt treatment is essential for liver transplant recipients.

[Rasha O Refaie, Yasmine M Massoud, Sahar Mohamed Lotfy, Mohamed A Rady Mahmoud S El Bokhary, Nahed A Makhlouf. Early Detection of Invasive Fungal Infections after Liver Transplantation: Single Center Experience. Life Sci J 2020;17(1):7-14]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 2. doi:10.7537/marslsj170120.02.

Key words: Fungal infection; liver transplantation; risk factors; Egypt

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Lean Muscle Gain Diet – A Study From The Saudi Food Market

Ahmed E. Altyar

Department of Pharmacy Practice, Faculty of Pharmacy, King Abdulaziz University, P.O. Box 80260 Jeddah 21589, Saudi Arabia

aealtyar@kau.edu.sa

Abstract: People become more concerned about their eating habits, especially when the food choices become harder to considered from such as the types and the prices which will affect the quality of the food. Operation research is a management science that changes the problem into mathematical equations to make it easier to solve and choose the optimal solution. By using linear programming to optimize the prices and the choices of food at its best. Operation research has many applications in life, this design will give an easier understanding of the problem, use of computer programs such as QM to solve problems that have more than three variables. This paper will make use of QM to get results in detail and graphs if possible. Thus, the design of cheap and possible lean muscle gaining diet is made easier for men who live in Jeddah. The nutrition food that used in this paper and helps people to build muscle are energy, vitamin b1, proteins, vitamin b3, carbohydrates, vitamin b6, vitamin b12, zinc, vitamin c, and calcium. The minimum optimal solution of this study is 13.81 when milk = 0.5, eggs =1.78, oranges=0.8, brown bread = 7.67 and spaghetti pasta = 13.57. The recommendation of this diet is that males who are looking to increase muscle mass and want to reduce overall cost without the risk of losing the health benefits.

[Ahmed E. Altyar. Lean Muscle Gain Diet – A Study From The Saudi Food Market. Life Sci J 2020;17(1):15-20]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 3. doi:10.7537/marslsj170120.03.

Keywords: diet; optimal; lean

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Three dimensional comparison of facial soft tissue changes between face mask and modified tandem appliances in unilateral cleft lip and palate cases

Ahmed Sh. Hashem, Wael M. Refai, Mohamed E. Saad, Omar S. Aboulmakarem, Mohamed Abdelghafar, Mohamed G. Elshall

Department of Orthodontics, Faculty of Dentistry, Minia University, Egypt

Abstract: Introduction: Correction of the three dimensional maxillary collapse in cleft lip and palate patients is considered as an extreme challenge to orthodontists. Growth modification including maxillary expansion and protraction is mandatory at an early age to adjust maxillary hypoplasia and enhance the facial esthetics. Aim: The aim of this study was to use CBCT to compare the facial soft tissue changes between the facemask and modified tandem appliances in the treatment of unilateral cleft lip and palate children with skeletal Class III malocclusion. Materials and Methods: 34 growing children suffering from surgically repaired unilateral complete cleft lip and palate with maxillary hypoplasia were randomly divided into 2 equal groups. The first group included 9 boys and 8 girls (9.1±1.2 years old) treated with hyrax expander and facemask. The second group included 7 boys and 10 girls (8.7±1.1 years old) treated with hyrax expander and modified tandem appliance. CBCT images were taken at the beginning of the treatment (T1) and after 1mm overjet was attained (T2) to compare the soft tissue profile changes between both groups. Results: In each group, there were significant decreases in the nasolabial angle and the facial convexity angle with significant increases in the H angle and the upper lip protrusion (P < 0.05). However, the lower lip protrusion showed insignificant change (P ˃ 0.05). There was insignificant difference in all parameters between both groups (P ˃ 0.05). Conclusions: Both the facemask and the modified tandem appliances are effective in improving the facial soft tissue profile in unilateral cleft lip and palate patients.

[Ahmed Sh. Hashem, Wael M. Refai, Mohamed E. Saad, Omar S. Aboulmakarem, Mohamed Abdelghafar, Mohamed G. Elshall. Three dimensional comparison of facial soft tissue changes between face mask and modified tandem appliances in unilateral cleft lip and palate cases. Life Sci J 2020;17(1):21-28]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 4. doi:10.7537/marslsj170120.04.

Key Words: Cleft lip and palate; Face mask appliance; Modified tandem appliance; Facial soft tissue profile

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Stentless Duct to Duct Biliary Anastomosis in LDLT Recipients with en Bloc High Hilar Dissection: Outcomes and Complications

Mohamed Ahmed Rady MD¹, Ahmed Adel Abbas Abdelshafy MD¹, Mohamed Abdelsattar Abdelhamid MD¹, Rasha O. Refaie, MD ², Dalia F Ahmy Emam³.

¹Department of General surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

²Department of Internal Medicine, Faculty of Medicine, Helwan University, Cairo, Egypt.

³Department of Anesthesiology, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email: mohamed_omran@med.asu.edu.eg; Phone: +201001078280

Abstract: Introduction: Biliary reconstruction of living donor grafts was done either by Roux-en-Y enteric anastomosis or duct to duct anastomosis duct-to-duct biliary anastomosis is considered nowadays the preferred procedure with many advantages over the Roux-en-Y hepatico-jejunostomy including, 1) avoiding the reflux of enteric contents into the biliary tree with decreasing the incidence of cholangitis; 2) faster and easier technique; and 3) maintaining the continuity of the bile duct which enables endoscopic access post operatively if needed. Patient and method: Between February 2017 and February 2019 a total of 125 LDLT cases were transplanted in Ain Shams University Specialized Hospital and Wadi-Elneel hospital by the same surgical team, 25 cases were excluded due to different causes and the remaining 100 cases were randomly divided in to two groups according to their biliary anastomosis into 2 groups, Group (A) duct to duct anastomosis with intraductal trans-anastomotic external biliary stent (DDS) and Group (B) direct duct to duct anastomosis without stent (DDD). We compared the results of both methods of biliary reconstruction as regards the biliary complications namely bile leaks or fistula, anastomotic biliary strictures, and ascending cholangitis. Results: The incidence of bile leakage and biliary stricture were higher in group B (DDD) (10%) and (14%) than in group A (DDS) (6%) and (8%) respectively, however this was statistically insignificant, In both groups bile leakage was managed conservatively, while Biliary strictures were managed by ERCP with balloon dilation and plastic stent insertion. The incidence of cholangitis is lower in DDD occurred only in 3, while occurred in 6 patients in DDS group which also, statistically insignificant. Conclusion: Stentless duct to duct biliary anastomosis in LDLT with en bloc high hilar dissection in both donor and recipient seems to be better choice after adding isolated stent morbidity with comparable incidence of postoperative biliary complications.

[Mohamed Ahmed Rady, Ahmed Adel Abbas Abdelshafy, Mohamed Abdelsattar Abdelhamid, Rasha O. Refaie, Dalia FAhmy Emam. Stentless Duct to Duct Biliary Anastomosis in LDLT Recipients with en Bloc High Hilar Dissection: Outcomes and Complications. Life Sci J 2020;17(1):29-36]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 5. doi:10.7537/marslsj170120.05.

Keywords: Duct to duct anastomosis, LDLT, stricture, leak.

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Experimental Study of Behavior of Reinforced Concrete Columns with added Steel Fiber after Fire Exposure

Mostafa Abdel Megied Osman ¹, Sherif Olwan² and Radwa Omar Mohamed³

¹ Assoc. Prof., Faculty of Engineering, Helwan University, Egypt.

² Assoc. Prof., Faculty of Engineering, The High Institute of Engineering, El-Shorouk, Egypt.

³ B.Sc., Civil Eng., Faculty of Engineering, The High Institute of Engineering, El-Shorouk, Egypt.

m_osman62@yahoo.com

Abstract: The present study aims to evaluate the improvement of the general behavior of reinforced concrete columns strengthened by steel fiber after exposed to fire (Elevated Temperature). Ten R.C. columns with a circular cross section of 200 mm in Diameter and 1250 mm in Height and with different ratios of steel fibers in concrete mix (0.50%, 1.0% and 1.50%), were fabricated, then exposed to fire (Elevated Temperature), and different methods of fire-fighting were loaded up to failure. The results show that the strengthening with steel fiber increased the load capacity and stiffness of R.C. columns compared to control specimens. Exposing RC columns to fire causes deterioration in its behavior and of load capacity.

[Mostafa Abdel Megied Osman, Sherif Olwan and Radwa Omar Mohamed. Experimental Study of Behavior of Reinforced Concrete Columns with added Steel Fiber after Fire Exposure. Life Sci J 2020;17(1):37-46]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 6. doi:10.7537/marslsj170120.06.

Keywords: Experimental; Study; Behavior; Reinforced Concrete Column; Steel; Fiber; Fire Exposure

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Incidence and Management of Early Complications of Laparoscopic Sleeve Gastrectomy for morbid obesity; Case series and Literature Review

Waleed Ibrahem, Mohamed Ahmed Rady, Mohamed Abdelsattar Abdelhamid, Mohamed G Qassem.

General Surgery Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email: Wibrahem50@gmail.com

Abstract: Background: One of the most common operation for weight loss is the laparoscopic sleeve gastrectomy which are an effective and relatively safe. Diagnosis of leakage is mainly based on clinical suspicion and lab radiological evidence. The Laparoscopic sleeve gastrectomy is superior in comparison to other restrictive procedures due to the decrease of large parts of ghrelin producing stomach mass. Aim of work: To estimate the incidence of early complications following laparoscopic sleeve gastrectomy and how to manage those complications. Patients and Methods: This study is a prospective case series which has been conducted at Ain Shams University Hospitals recruiting 300 patients who underwent laparoscopic sleeve gastrectomy upon between March 2017 and March 2018 with minimal follow up of one month postoperatively. Prospective data were reviewed from patient files. Results: Our study included 300 patients with mean age 37.1 ± 20. The mean body mass index was 41.95 ± 4 while body mass index (BMI)< 40 kg/ m² was 5% and BMI was 40 -50 kg/ m² was 95%. Medical co-morbidities were in the form of hypertension in 30% of cases, DM in 40% of cases and obstructive sleep apnea in 6% of cases. The operation time was 30-40 min and the average of hospital stay was 1.2 (1-4) days. The postoperative complications were staple line leakage in 0.6% of the cases, staple line he in 0.6% of cases, wound infection in 0.3% of cases, portal vein thrombosis in 0.3% of cases and chest infection in 0.6% of cases. Conclusion: Leakage and hemorrhage after LSG are diagnosed clinically and by radiological investigations. Mesenteric Venous Thrombosis is a subtle complication that warrants high index of suspicion for immediate management. Further studies are needed to detect the best treatment methods for early complications.

[Waleed Ibrahem, Mohamed Ahmed Rady, Mohamed Abdelsattar Abdelhamid, Mohamed G Qassem. Incidence and Management of Early Complications of Laparoscopic Sleeve Gastrectomy for morbid obesity; Case series and Literature Review. Life Sci J 2020;17(1):47-56]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 7. doi:10.7537/marslsj170120.07.

Keywords: Laparoscopic Sleeve Gastrectomy, early complications, leakage, hemorrhage.

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The effect of stoma size on the midterm weight loss outcome of single anastomosis gastric bypass (SAGB): A double-blinded prospective randomized trial

Ahmed Elgeidie, MD¹. and Waleed Ibrahim, MD²

¹Gastrointestinal Surgery Center, Mansoura University, Egypt

²General Surgery Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Wibrahem50@gmail.com

Abstract: Background: Single anastomosis gastric bypass (SAGB) is gaining a wide spread acceptance among bariatric surgeons all over the world because of technical simplicity and documented efficacy. Till now the relation between stoma size in SAGB and weight loss outcome had not been addressed. Objectives: To evaluate the effect of stoma size on the mid-term weight loss outcome for obese patients underwent SAGB. Materials and Methods: This is a double-blinded prospectively randomized trial. From March 2014 to September 2016, morbidly obese patients who were submitted for SAGB were included in the study. SAGB was performed according to the known technical procedures, with the exception of for the size of the GJ. Patients were divided randomly into two equal group; narrow GJ group (30 mm) and wide GJ group (45mm). After procedure the percentage of excess weight loss (%EWL) was estimated at a period of 6, 12 and 24 months. Results: Eighty three patients were eligible for enrollment in the study. They were randomly classified into 2 groups; narrow GJ group (n = 42) and wide GJ group (n = 41). The mean ages were 32 and 39.4 years, and there were 32 and 34 females in the narrow GJ and wide GJ groups, respectively. The decline in the BMI was greater in the narrow GJ group at 6 months follow up, while, generally, over time the two groups had significant decline of BMI. At 12 and 24 months the %EWL difference between the two groups disappeared. Conclusion: The size of GJ at SAGB has no significant impact on weight loss at mid-term follow up.

[Ahmed Elgeidie and Waleed Ibrahim. The effect of stoma size on the midterm weight loss outcome of single anastomosis gastric bypass (SAGB): A double-blinded prospective randomized trial. Life Sci J 2020;17(1):57-60]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 8. doi:10.7537/marslsj170120.08.

Keywords: Obesity, single anastomosis gastric bypass, gastrojejunostomy size.

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Results of Open reduction and internal fixation of posteromedial tibial plateau fractures through posteromedial approach

Anas H. Elgarya¹, Ali M. Emran², Muhammad A. Quolquela³, Mostafa H. Hegazy⁴

¹Resident of orthopedic surgery, Department of Orthopedic Surgery, Tanta University, Egypt.

²Lecturer of orthopedic surgery, Department of Orthopedic Surgery, Tanta University, Egypt.

³Assistant Professor of orthopedic surgery, Department of Orthopedic Surgery, Tanta University, Egypt.

⁴ Professor of orthopedic surgery, Department of Orthopedic Surgery, Tanta University, Egypt.

E mail:dr_anashosny@yahoo.com

Abstract: Background: Fractures of the tibial plateau or tibial condyles can represent serious intraarticular injuries and constitute approximately 1% of all fractures. The spectrum of injury extends from less severe fractures of an isolated plateau that may be treated non surgically with excellent results to devastating involvement of the entire plateau (and often the proximal tibialmetaphysis) requiring extensive surgery. These severe injuries may result in posttraumatic premature arthritis, ligamentous injury, and lifelong pain and disability. Materials and Methods: 21 patients with posteromedial tibial plateau fractures either alone or combined by other columns fractures underwent open reduction and internal fixation through posteromedial approach, assessment was done using Rasmussen scoring system.Results:17 patients achieved satisfactory results (twelve excellent - five good) representing 81% of all cases, three cases had fair outcome (14.2%) and one case had poor outcome (4.8%), one case had superficial wound infection and two cases had stiffness. Conclusion: The posteromedial approach involves smaller incision, safe and good exposure for reduction of the posteromedial fragment, and plate fixation allows rigid fixation with early range of motion postoperatively.

[Anas H. Elgarya, Ali M. Emran, Muhammad A. Quolquela, Mostafa H. Hegazy. Results of Open reduction and internal fixation of posteromedial tibial plateau fractures through posteromedial approach. Life Sci J2020;17(1):61-67].ISSN: 1097-8135 (Print) /ISSN: 2372-613X (Online).http://www.lifesciencesite.com. 9.doi:10.7537/marslsj170120.09.

Key Words: Posteromedial, Tibial plateau fractures, posterior column buttress plate.

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Effect of Al & Fe inorganic polymers on the enhancement of the surface properties of Activated carbon prepared from sesame stalks

Hamed M. Al–Saidi¹, Othman A. Farghaly², Mohamed E. A. El-Sayed^*3, Mohamed Abd- Elmottaleb¹, Taha A. Elmaghraby³, Mahmoud G. Z. Ahmed³

¹Chemistry Department, University College in Al–Jamoum, Umm Al–Qura University, 21955, Makkah, Saudi Arabia.

² Faculty of Science, Al-Azhar University, Assiut Branch, 71524 Assiut, Egypt.

³ Soils, Water and Environmental Research Institute, Agriculture Research Center, El-Giza, Egypt.

*Corresponding author: (Mohamed El-sayed, eid1592003@yahoo.com)

Abstract: Activated carbon (AC) has a high demand throughout the world that towards to minimize the cost of production and materials reuse. Recently, many research have focused on the enhancement of the properties of AC by applying various materials and methods. In this study, AC prepared from Sesame stalks as (SSAC) and modified using two inorganic polymers (Al_x (OH)_y and Fe_x (OH)_y) to obtain AlAC and FeAC respectively. BET, SEM, EDX and FTIR were used to characterize the samples, the BET surface area of SSAC, AlAC and FeAC were 190.039, 206.167, 378.404 m²g^-1 respectively, and the volume of pores had increased in AlAC and FeAC comparing with SSAC. SEM showed that the surface of AlAC and FeAC were filled with some rod-like structures as it could be a result of the structural change of AC in the adsorption of Al and Fe polycations species. Overall, the analysis of the samples indicates that the inorganic polymers probably have a substantial effect on the structure and morphology of the samples, but indicate certain differences in their physical/chemical properties. The results prove that the modification of AC with inorganic polymers could be an interesting way to improve adsorption properties.

[Hamed M. Al–Saidi, Othman A. Farghaly, Mohamed E. A. El-Sayed, Mohamed Abd- Elmottaleb, Taha A. Elmaghraby, Mahmoud G. Z. Ahmed. Effect of Al & Fe inorganic polymers on the enhancement of the surface properties of Activated carbon prepared from sesame stalks. Life Sci J 2020;17(1):68-74]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 10. doi:10.7537/marslsj170120.10.

Keywords: Activated carbon; Modification; Inorganic polymers; BET; SEM

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[Life Sci J 2020;17(1):75-79]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 11.

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Haematological And Biochemical Parameters Of Broiler Chickens Fed Processed Or Raw Tropical Sickle Pod (Senna obtusifolia) Seed Meal Based-Diets

Augustine, C^*1., Igwebuike, J.U²., Kwari, I.D²., Adamu, S.B²., John, T., Zakaria, A¹., Ardo, M.U., Katsala, J.G³., Obidah, L.U¹., Maspalma, A.J³. Shall, M.P. and Ahmed S

^1.  Department of Animal Production, Adamawa State University, Mubi, Nigeria.

^2.  Department of Animal Science, University of Maiduguri, Nigeria.

^3.  Department of Agricultural Education, College of Education, Hong, Nigeria ^4. Department of Home Economics, College of Education, Hong, Nigeria audaggai@gmail.com

Abstract: A feeding trial was conducted for eight (8) weeks to evaluate the haematological and biochemical indices of broiler chickens fed processed or raw tropical sickle pod (Senna obtusifolia) seed meal-based diets. Six (6) experimental diets were compounded to contain 0% and 20% each of the raw, boiled in water, soaked in water, sprouted and boiled and fermented Senna obtusifolia seed meal designated as T1, T2, T3, T4, T5 and T6, respectively. Two hundred and sixteen (216) broiler chicks were randomly allotted to the six dietary treatments in a randomized complete block design (RCBD) with pen location serving as the blocking factor. Each replicate contained 12 chicks each. At the end of the experiment, blood samples were collected using standard procedure. Each representative blood sample was analyzed in triplicates for packed cell volume (PCV), haemoglobin (Hb), red blood cell (RBC) and white blood cell count (WBC). The erythrocytic indices (mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were computed using standard formula. The blood samples were also analyzed for serum total protein, albumin, globulin, uric acid, cholesterol, creatinine, electrolytes, enzymes and bilirubin. The haematological parameters were significantly (P<0.05) affected by the dietary treatments except for the Hb, RBC, MCH and MCHC. The lowest PCV (25.54%) was recorded in broiler chickens fed raw Senna obtusifolia seed meal-based diets. The Highest WBC value (2.71x10³/ml) was also observed in broiler chickens fed the raw Senna obtusifolia seed meal-based diet. Better haemological values were observed in broiler chickens fed the control diet (T1, 0% SOSM) and processed Senna obtusifolia seed meal-based diet with those fed the fermented seed meal-based diet recording better haematological status. The biochemical parameters were significantly (P<0.05) affected by the dietary treatments except for the globulin. The broiler chickens fed the raw Senna obtusifolia seed meal-based diet recorded the lowest values for total protein (1.97 g/dl), albumin (1.52 g/dl) and cholesterol (22.1 mg/dl). The concentration of serum electrolytes similarly followed similar pattern as that of the total protein, albumin and cholesterol. Low values for calcium (2.17 mmol/L) and phosporus (2.07 mmol/L) were recorded in broiler chickens fed the raw Senna obtusifolia seed meal-based diet. However, better serum electrolytes values were recorded in the chickens fed the processed Senna obtusifolia seed meal-based diets with those fed the fermented Senna obtusifolia seed meal-based diet indicating better electrolytes status. Serum enzymes and bilirubin levels were observed to be significantly (P<0.005) elevated in broiler chickens fed the raw Senna obtusifolia seed meal-based diet. Aspartate aminotransferase and alanine aminotransferase were 9.27 and 8.53µ/L in the broiler chickens fed raw Senna obtusifolia seed meal (RSOSM) based-diet. Similarly, high level of bilirubin (16.38 mmol/L) was observed in broiler chickens fed RSOSM-based diet. It was concluded that better haematological and biochemical status were observed in the broiler chickens fed 20% fermented Senna obtusifolia seed-meal based diet and is therefore recommended for inclusion in the diets of broiler chickens. 

[Augustine, C., Igwebuike, J.U., Kwari, I.D., Adamu, S.B., John, T., Zakaria, A., Ardo, M.U., Katsala, J.G., Obidah, L.U., Maspalma, A.J. Shall, M.P. and Ahmed S. Haematological And Biochemical Parameters Of Broiler Chickens Fed Processed Or Raw Tropical Sickle Pod (Senna obtusifolia) Seed Meal-Based Diets. Life Sci J 2020;17(1):80-91]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 12.

doi:10.7537/marslsj170120.12.

Keywords: Biochemical and haematological parameters, processed Senna obtusifolia seed

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