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Effect of Parathyroid Hormone and Body Mass Index on Overall Stability Index in Saudi Males with Vitamin D deficiency

Omar Farouk Helal ¹, Osama Adnan Kensara², Firas Sultan Azzeh², Ehab Mohamed Abd El-Kafy^1,3

¹Department of Physical Therapy, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, KSA.

²Department of Clinical Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, KSA.

³Department of Physical Therapy for Disturbances of Growth and Developmental Disorders in Children and Its Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt

ofhelal@uqu.edu.sa

Abstract: The purpose of this study is to determine the correlation between parathyroid hormone (PTH) and body mass index (BMI) on the overall stability index (OSI) in Saudi males with vitamin D deficiency. Method: A total of 669 adult Saudi males with mean age of 19.9 years suffering from vitamin D deficiency were participated in this study. The subjects were divided according to their PTH status into two groups; group 1 (n=619) having a normal PTH values; and group 2 (n=50) suffering from hyperparathyroidism. Participants were also categorized based on their BMI into; underweight (BMI<17.9), normal (BMI=18-24.9), overweight (BMI 25-29.9), and obese (BMI>30). The OSI protocol was used to compare vitamin D deficiency subjects’ that having normal PTH values with those suffering from hyperparathyroidism for different BMI categories. The Biodex Balance System was used to measure the OSI values. Results: No significant differences were observed between normal and high PTH groups in age, weight, height, BMI, OSI, vitamin D, calcium, phosphorus, and alkaline phosphatase. A significant positive correlation between OSI and PTH (r=0.135, P=0.011) was perceived. The results also revealed that the BMI had a significant positive association with OSI (r=0.521, P<0.001). In addition, BMI had positive correlation with PTH (r=0.109, P=0.042). The highest average OSI value was observed in the subjects having both obesity and hyperparathyroidism. Conclusion: The PTH and BMI have a positive correlation with OSI, which means that hyperparathyroidism and obesity synergistically increase the risk of falling in Saudi males with vitamin D deficiency.

[Helal OF, Kensara O, Azzeh F, and Abd El-Kafy EM. Effect of Parathyroid Hormone and Body Mass Index on Overall Stability Index in Vitamin D deficient Saudi Males. Life Sci J 2016;13(2):1-6]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 1.

doi:10.7537/marslsj130216.01

Key words: Parathyroid Hormone; Body Mass Index; Overall Stability Index

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Efficiency of planning and implementation of individualized educational program for students with disabilities from the point of view of parents in Jeddah

Hussein Abdulmajid Al- Najjar¹ and Khaled Mohammed El-Rashedy²

¹Associate Prof. in Special Education, University Kingdom of Saudi Arabia, King Abdulaziz University. Institute of Educational Graduate Studies. Department of Special Education. P.O. Box: 80269, Jeddah: 21589

Ph: +966507573278. E-mail: dr.hussein_2007@yahoo.com

²Associate Prof. in Special Education, Kingdom of Saudi Arabia, King Abdulaziz University, Institute of Educational Graduate Studies, Department of Special Education, P.O. Box: 80269, Jeddah: 21589

Ph: +966542920459. E-mail: khaledelrashedy@yahoo.com

Abstract: This study aimed to determine the level of efficiency of the planning and implementation of individualized educational program for students with disabilities in Jeddah city from parents' point of view. The study sample consisted of 150 of parents of students with disability in Jeddah city. A questionnaire was prepared for this purpose and applied to the sample. The results indicated that parents' estimation of both efficiency and obstacles of the planning and implementation of individual educational program was moderate. The results also indicated that there were no statistically significant differences in parents' opinions about the efficiency and the obstacles of the planning and implementation of individual educational program regarding the variables of type of disability, parent education, and income.

[Hussein Abdulmajid Al- Najjar and Khaled Mohammed El-Rashedy. Efficiency of planning and implementation of individualized educational program for students with disabilities from the point of view of parents in Jeddah. Life Sci J 2016;13(2):7-16]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 2.

doi:10.7537/marslsj130216.02

Key words: Individualized educational program, views of parents.

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Geminated Tooth with Succedaneous Supernumerary Tooth: Case Report in Jeddah, Saudi Arabia

Alostaz M.A.¹, AlFadhl H.A.², Damanhouri W.H. ³, Attar M.H.⁴

¹Intern Dental Student, Batterjee Medical College for Science and Technology, Faculty of Dentistry, Jeddah, Saudi Arabia.

² BDS, MSC in Pediatric Dentistry, Batterjee Medical College for Science and Technology, Faculty of Dentistry, Jeddah, Saudi Arabia.

³ BDS, MSC, ABPD in Pediatric Dentistry, King Fahad Hospital, Head of Pediatric Dental Unit, Jeddah, Saudi Arabia.

⁴BDS, MSC, DScD, ABPD in Pediatric Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia and Batterjee Medical College for Science and Technology, Faculty of Dentistry, Jeddah, Saudi Arabia.

moazattar@gmail.com, emanashkmm@yahoo.com

Abstract: Dental anomalies can occur either in the size, shape, number or composition of the teeth. They are caused by disturbance during any stage of teeth development, but the exact etiology is unknown. They are more frequent in children with clefts especially supernumerary teeth and the double teeth. The aim: of this report is to document a case that represents geminated primary upper incisor with the presence of supernumerary tooth in primary dentition. Methods: A four years, six months old male presented in dental clinic in Batterjee Medical College of Science and Technology in Jeddah, Saudi Arabia.. His Chief complain was pain and pus in his anterior teeth. Two bitewing radiographs were taken which revealed a double tooth (geminate) with one root and one radicular pulp (pulp chamber) with supernumerary tooth apical to the double tooth. The double tooth was extracted (tooth number # 61), along with the supernumerary tooth (#62). Conclusion: Although the case of geminated tooth was associated with supernumerary tooth, no other anomalies like clefts was reported.

[Alostaz M. A., AlFadhl H.A., Damanhouri W.H., Attar M.H. Geminated Tooth with Succedaneous Supernumerary Tooth: Case Report in Jeddah, Saudi Arabia. Life Sci J 2016;13(2):17-21]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 3.

doi:10.7537/marslsj130216.03

Key words: geminate tooth, supernumery tooth, dental anomalies in children

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Cytotoxicity and Chemical Investigation of the Aerial Parts of Markhamiazanzibarica (Bojer Ex Dc.) K. Schum. (Bignoniaceae)

Dina M. El-Kersh⁽¹⁾, Riham S. El-Dine ⁽²⁾, Dina R. Abou-Hussein ^{(2, 3)}, Fatma S. El Sakhawy⁽²⁾, and Mohamed MoheyElmazar⁽⁴⁾

¹Department of Pharmacognosy, Faculty of Pharmacy, British University in Egypt (BUE), 11837, Egypt.

²Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, 11562, Egypt.

³Departement of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.

⁴Professor of pharmacology, Dean of Faculty of Pharmacy, British University in Egypt (BUE), 11837, Egypt.

dina.elkersh@bue.edu.eg

Abstract: The ethanolic extract of the aerial parts of Markhamiazanzibarica (Bignoniaceae) was tested for its cytotoxic activity against human cervical adenocarcinoma cell line (HeLa). It showed a potent effect with an IC₅₀ of 9.68 µg/ml compared to Doxorubicin (7.28 µg/ml). The fractions obtained from the successive partitioning of the total extract, were tested against the same cell line; the results revealed that n-hexane extract was the most potent 9.23 μg/ml, followed by ethyl acetate, butanol and chloroform fractions with IC₅₀ of 21.2, 22.4 and 49.6 µg/ml, respectively. Column chromatography led to the isolation of oleanolic acid (1), ursolic acid (2) and luteolin (3). The structures of the isolated compounds were elucidated using spectroscopic techniques.

[Dina M. El-Kersh, Riham S. El-Dine, Dina R. Abou-Hussein, Fatma S. El Sakhawy and Mohamed Mohey Elmazar. Cytotoxicity and Chemical Investigation of the Aerial Parts of Markhamiazanzibarica (Bojer Ex Dc) K. Schum (Bignoniaceae). Life Sci J 2016;13(2):22-26]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 4.

doi:10.7537/marslsj130216.04

Keywords: Markhamiazanzibarica, ursolic acid, oleanolic acid, luteolin, cytotoxicity, HeLa

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Incidence of Zoonotic Parasites In Egyptian Raw Vegetable Salads

Sylvia O. Ahmad¹; El Fadaly H. A.²; Mona S. Zaki³ and Barakat A. M. A.²

Department of animal Hygiene and zoonosis, Faculty of Veterinary Medicine, Assiut University Egypt.

Zoonotic Diseases Department, National Research Center, Giza, Egypt.

Prof. of Clinical Pathology, Hydrobiology Department, National Research Centre, Dokki, 12622, Giza, Egypt

ashrafbarakat2@hotmail.com

Abstract: Feeding on Vegetables which probably contaminated order to pre or post-harvesting activities through soil, animals or wastage water contacts, consider as non-neglected source for several zoonotic parasites. So, this study describes the possible parasites contamination in raw vegetables salads, directly reflect public health hazard. A total of 527 salad samples of seven varied types as; 94 sample of Onion, 93 Cucumbers, 88 dill & Parsley, 87 Tomatoes, 73 Lettuce, 51 cabbages and 41 carrots were collected from different types of restaurants within two Egyptian governorates (Mnia and Assiut). Samples were directly washed each by Tris-buffer-saline (TBS), followed by concentration of the extract by centrifugation, staining of the different stages by modified Zeihl–Neelsen stain centrifuged and the sediments were fast microscopic examined for parasites. The overall incidence of parasite contamination in each type of vegetable were; 7.4% in Onion, 22.6% in Cucumbers, 19.3% in Dill & Parsley, 13.8% in Tomatoes, 8.2 % in Lettuce, 15.7% in Cabbages and 34.5% in Carrots. Also, five types of parasites were detected by 16.1% in the total examined samples. Also, the overall incidence of each parasite reference to total vegetable samples were; Ascarislumbricoides (3.2%), Cryptosporidium parvum (1.7%), Entamoeba spp. cysts (3.4%), Giardia lamblia (2.8%), and Toxoplasma gondii (4.9%).The study validates some zoonotic parasites of public health worry in vegetables salad. The results alarm must be connected to the Egyptian health authorities for fast adjustment the public health educational progressions, and modified sterilization or radiation techniques for raw vegetable.

[Sylvia O. Ahmad; El Fadaly H. A.; Mona S. Zaki and Barakat A. M. A. Incidence of Zoonotic Parasites In Egyptian Raw Vegetable Salads. Life Sci J 2016;13(2):27-31]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 5.

doi:10.7537/marslsj130216.05

Key words: Zoonotic parasites, Vegetable Salads, Egypt

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Science of living enhance employment for the drug addicts towards the youth empowerment-A Holistic Approach from Malaysia

Mohammad Hannan Mia¹, Razaleigh Muhamat Kawangit¹, Abd Ghafar Hj Don¹, Nowshad Amin²

¹ Department of Da’wah and Leadership Studies, Faculty of Islamic Studies, National University of Malaysia, 43600, Bangi, Selangor, Malaysia

² Department of Electrical, Electronic and System Engineering, Faculty of Engineering and built environment, National University of Malaysia, 43600, Bangi, Selangor, Malaysia

dr.hanan@ukm.edu.my

Abstract: The purpose of this research is to perform an empirical analysis the factors affecting science of living for the drug addicts towards the youth empowerment. For statistical estimations used descriptive models of analysis. The results of this study show that the science of living enhance employment for the addicts towards the youth employment for empowering through a holistic way prescription from Quran and Hadith is influenced by value their education, employment, financial development and the development nature (committed to work rather than choose) of the addicts. It is also found that science of living reduces the risks of unemployment for the youth. There has been growing concern over the erosion of values among drug addicts for empowering them through science of living with employment. Taking into account self-exploratory and scientific methodology conducted between Kolej Komuniti Hulu Langat (KKH, Selangor with SIDIM (Sahabat Insan Dan Iman Malaysia). It is also found that technical education designed science of living itself as well as employed them. This model is panacea and holistic model for them to treat the addicts heart makes them ready to work for happy life. The main objective of the study is to understand the science of living as a means of youth empowerment. More specifically, the study aims to analyze the science of living has impacted all domains of the addicts’ personality and it has developed a healthy and positive morality.

[Mohammad Hannan Mia, Razaleigh Muhamat Kawangit, Abd Ghafar Hj Don, Nowshad Amin. Science of living enhance employment for the drug addicts towards the youth empowerment-A Holistic Approach from Malaysia. Life Sci J 2016;13(2):32-37]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 6.

doi:10.7537/marslsj130216.06

Keywords: Science of living, the addicts, youth empowerment, holistic treatment

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Evaluation of the Role of Pharmacists in Community Setting in Jeddah, Saudi Arabia

Abdulrahman Alahdal¹, Namareq Aldardeer ², Lama Baghaffar ³, Nuha Alshahrani ³, Bodoor Saber ³

Alaa Bagalagel⁴

^1,Vice-dean for Clinical Training and Development, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia

Associate Professor, Clinical Pharmacy Department, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia

² Pharmacist I, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia

³ Pharmacist, King Abdulaziz University, Jeddah, Saudi Arabia

⁴ Assistant Professor, Clinical Pharmacy Department, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia

abagalagel@kau.edu.sa

Abstract: Objectives: This study was conducted to evaluate current performance of community pharmacists and provided services in community pharmacies in Jeddah to praise the necessary changes in order to meet international standards. Method: A questionnaire composed of six sections (total of forty-eight questions) centered on the pharmacist and the pharmacy itself was randomly distributed to 99 pharmacies in Jeddah that was divided into four regions (North, South, East, and Middle-West). Results: Ninety-five out of ninety-nine pharmacists have a bachelor degree; all of them were non-Saudi males. The average number of pharmacists in each pharmacy during working hours was 1-2(86%) of pharmacies. Seventy-one percent were aware of the ADR reporting program. Twenty-nine percent dispense prescribed medication without a prescription; 57% deals with trade names. Eighty-seven percent of pharmacists claimed that they provide patient counseling; seventy-eight percent deal with medication errors. Fifty tow percent don't communicate with doctors. Only 37% of pharmacies have a website while 8% of them provide online services and delivery. Twenty-five percent of pharmacists provide educational programs for chronic disease. Sixty for percent of pharmacists claimed to have enough training and supervision from their administrations and only 6% showed no interest in getting more information on current pharmacy practice and new drugs. Conclusion: After evaluating the pharmacists working in community pharmacies and the services provided, this study has proved that many important services were lacking and that development in necessary in order to meet the international standards of pharmacy practice.

[Alahdal A, Bagalagel A. Evaluation of the Role of Pharmacists in Community Setting in Jeddah, Saudi Arabia. Life Sci J 2016;13(2):38-46]. ISSN 1097-8135 (print); ISSN 2372-613X (online). http://www.lifesciencesite.com. 7. doi:10.7537/marslsj130216.07

Keywords: Community; Pharmacists; Saudi Arabia, Services

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Concentration of 226Ra, 232Th and 40K Radionuclides in Natural Products Commonly Used as Cosmetics Materials

Afaf A. Fakeha and J. H. Al- Zahrani

Physics Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia

afafageha@yahoo.com, jam7474@hotmail.com

Abstract: Natural product samples used as cosmetic materials were collected from various markets in Saudi Arabia, analyzed using a high purity germanium detector (HPGe) to determine radioactivity concentrations of the natural radionuclides 226Ra, 232Th and 40K. The obtained concentrations for 226Ra and 232Th ranged from 0.65±0.17 to 6.47±1.07and from 0.34±0.11 to 8.54±1.16 Bq kg^-1, respectively, while the concentration of 40K ranged from 10.62±0.35 to 1202.84±15.95Bq kg^-1, with overall mean values of 2.72, 3.73 and 444.09 Bq kg^-1 respectively. The mean values of radium equivalent, absorbed dose rate and the annual effective dose of the samples under study were determined as 42.25 Bq kg^-1, 22.58 nGyh^-1 and 0.028 mSvy^-1, respectively. The present results are lower than the permitted limits and are found to be safety for the human usage.

[Afaf A. Fakeha and J. H. Al- Zahrani. Concentration of 226Ra, 232Th and 40K Radionuclides in Natural Products Commonly Used as Cosmetics Materials] Life Sci J 2016;13(2):47-50]. (ISSN:1097-8135).http://www.lifesciencesite.com. 8.

doi:10.7537/marslsj130216.08

Keywords: Natural radioactivity, Cosmetic materials

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Identification of contaminated soil from isolated fungi in Riyadh province

Fahad Abdullah M. Al-Dhabaan^1*, Ali Hassan Bakhali¹

^1.  Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.

Email: fahadalahmari2003@gmail.com; Tel: 00966-504893691; Fax: 00966-504893691

Abstract: The chemical and microbiological (on the basis of fungi) analysis of the soils was carried out in the Riyadh region with thirteen mycobiota samples, which were surveyed in Explosive Institute in Riyadh. This study aims to explore does isolated fungi in contaminated soils can be used as bioremediation agents for explosive materials. High significant differences in fungal frequency between presented in five regions. Fungal distribution analysis was performed by dilution plating of the explosive-contaminated soil. The fungal genera found in explosive-contaminated soil in the state in order of decreasing predominance were Fusarium sambucinum, Chaetomium globosum, Nigrospora sacchari, and Ulocladium chartarum. From the present study we conclude that some of the isolated fungi of contaminated soils can be used as bioremediation agents for explosive materials.

[Fahad Abdullah M. Al-Dhabaan^, Ali Hassan Bakhali. Identification of contaminated soil from isolated fungi in Riyadh province. Life Sci J 2016;13(2):51-56]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 9.

doi:10.7537/marslsj130216.09

Keywords: Mycology, soil, fungi, contaminate

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Design and Synthesis of quinazoline derivatives: Biological evaluation for their Anticancer and VEGFR inhibitory activities.

Wegdan M. Metwally^a*, Gehan Hegazy^b, Sameh Eid^d, Rabah A.T. Serya^d, Dalal A. Abou El Ella^d.

^a Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Modern Science and Arts University, 6th of October City,Cairo, Egypt

^b Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Kaser-El-Eni, Cairo, Egypt.

^c Department of Pharmaceutical Sciences, University of Basel, Biozentrum, Klingelbergstrasse 50, 4056 Basel, Switzerland.

^d Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Abbasia, Cairo, Egypt.

wegdan_metwally@hotmail.com

Abstract: In this thesis a series of novel 4-substituted quinazoline derivatives was rationally designed, synthesized and biologically evaluated for their anticancer activity. The sixteen synthesized compounds IVa-f, Va-d, VIa-d and VIIa, b were evaluated for their antitumor activity against MCF7 and HEPG2 cell lines at National Cancer Institute (NCI, Egypt). Eight of these compounds IVc, IVf, Vc, VIa-d, VIIb were selected due to their promising activity against the cell lines to be tested in vitro against VEGFR2 inhibition in KINEXUS cooperation, Canada. Compound VIa show marked inhibitory activity against VEGFR2 (52%). The obtained results were clarified using molecular modeling study using grid-based ligand docking with energetics glide program. The design depends on exploration of the previous revealed SAR studies, identification of the key interactions with the binding site and bioisosteric modifications of the reference compound 6.

[Wegdan M. Metwally, Gehan Hegazy, Sameh Eid, Rabah A.T. Serya^, Dalal A. Abou El Ella. Design and Synthesis of quinazoline derivatives: Biological evaluation for their Anticancer and VEGFR inhibitory activities. Life Sci J 2016;13(2):57-68]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 10.

doi:10.7537/marslsj130216.10

Key words: Anticancer; quinazoline derivatives, kinase inhibitors

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cPrevalence of ABO and Rh Blood Groups in Saudi Arabian Population

Elaf Junainah⁽¹⁾, Saeed Al-Amoudi⁽²⁾, Jamal Junainah⁽³⁾, Yahya El-ficki ⁽⁴⁾, Eman Baothman⁽⁵⁾, Abdulazziz Andijani⁽⁶⁾, Hadir Mir⁽⁷⁾, Sahar al fatta⁽⁸⁾, Muhannad Qarah⁽⁹⁾

¹Research Assistant And Coordinator, King Abdul Azziz Hospital, KSA.

²Consultant Hematologist, Hematology Department, King Abdul Azziz Hospital Jeddah, KSA.

^3-4Consultant Internal Medicine, Internal Medicine Department, King Abdul Azziz Hospital, KSA.

^5-6Research Assistant, King Abdul Azziz Hospital, KSA.

⁷Consultant Nuclear Medicine, Nuclear Medicine Department, King Abdul Azziz Hospital, KSA.

⁸Consultant Pediatrician, Pediatrics and Neonatology Dept. King Abdul Azziz Hospital, Jeddah, KSA.

⁹Research Assistant And Publishing Supervisor, Internal Medicine Department, King Abdulazziz Hospital, Jeddah, KSA.

profelficki@yahoo.com

Abstract: ABO and rhesus (Rh) blood group antigens are the most frequently studied genetic markers in a large group of people. The knowledge of the distribution of ABO and Rh blood groups is essential for effective management of blood banks inventory, be it a facility of smaller local transfusion service or a regional or national transfusion service. Apart from the importance in blood transfusion practice, the ABO and Rh blood groups are useful in population genetic studies, researching population migration patterns as well as resolving certain medico-legal issues, particularly of disputed parentage. The present study was done to assess the prevalence of blood groups in different categories in Jeddah province and to compare our results with other studies conducted in KSA and elsewhere in the world and its multipurpose future utilities for the health planners. In our study, Determined the ABO group and Rh blood group for 800 Saudi population. The participants for this study were the blood donors coming to King Abdul Aziz hospital (KAAH) blood bank, in the period of November, December 2015, and January2016. They were from different ages and from numerous and diverse national and cultural backgrounds, who either donate blood regularly or to cover hospital needs. The overall distribution of blood group in our sample study was 53%, 24%, 18%, 6% for groups O, A, B, and AB respectively. While the prevalence of Rh (D-antigen) blood typing was 91% Rh positive and the remaining 9% was Rh negative.

[Elaf Junainah, Saeed Al-Amoudi, Jamal Junainah, Yahya El-ficki,Eman baothman, Abdul Azziz andijani, Hadir mir, Sahar al fatta, and Muhammad Qarah. Prevalence of ABO and Rh Blood Groups in Saudi Arabian Population. Life Sci J 2016;13(2):69-73]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 11.

doi:10.7537/marslsj130216.11

Keywords: ABO Blood Groups, Rh prevalence, Blood Banks KSA

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A Novel Knee Shaped Patch Antenna For Mimo Communications

Fahd baabdullah, Adnan Affandi, & Abdullah M. Dobaie

Dept., of Elect. & Comp. Eng, Faculty Of Eng, King Abdulaziz University, Jeddah, KSA

fahd.baabdullah9@gmail.com

Abstract: A compact two element MIMO (Multiple Input Multiple Output) system is proposed using a Knee shaped patch antenna giving an impedance bandwidth of 22.85 % and resonating at a frequency of 7.1 GHz. The proposed MIMO system offers improved bandwidth, return loss and good isolation characteristics. The developed system resonating at 7.1GHz frequency for VSWR≤2 can be used for 4G & WiMAX applications. The simulation results of return loss, mutual coupling and gain are presented.

[Fahd baabdullah, Adnan Affandi, & Abdullah M. Dobaie. A Novel Knee Shaped Patch Antenna For Mimo Communications. Life Sci J 2016;13(2):74-77]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 12.

doi:10.7537/marslsj130216.12

Keywords: Knee shaped patch antenna, MIMO systems, impedance bandwidth, mutual coupling

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The application of Hector Battifora Mesothelial-1, CITED-1 and Fibronectin-1 in differential diagnosis of thyroid follicular neoplasms.

Aliaa Atef and Mohammed Elrashidy

Department of Pathology, Faculty of Medicine, Tanta University, Egypt.

dr-aliaaatef@hotmail.com

Abstract: Background: The differentiation of benign from malignant follicular thyroid neoplasms remains difficult and some controversial results have been reported for the immunohistochemical markers of malignancy proposed so far. Nodular tumors exhibiting a predominantly follicular architecture are the most common presenting and confusing pattern of thyroid neoplasms. They can be benign as follicular adenoma (FA) or malignant as papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC). Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. Material and methods: This study was carried out on 176 thyroid specimens received as paraffin blocks (84 FA, 50 PTC and 42 FTC) using three markers HBME-1, CITED-1 and FN-1. Results: All three markers combined were positive in 23 malignant cases with no combined positivity in the benign cases. CITED-1 was positively expressed in 65 malignant thyroid lesions (50 PTC and 15 FTC). HBME-1 was positive in 58 malignant cases (46 PTC and 12 FTC). FN-1 was positive in 52 malignant cases (46 PTC and 6 FTC). At least for 2 positive markers, regardless of which two, the sensitivity for the detection of malignancy was 58.7% with 100% specificity while single marker immunoreactivity increased sensitivity but markedly reduced specificity. CITED-1, HBME-1 and FN-1 expression was statistically significant in PTC cases than their expression in FTC. Conclusions: A panel of HBME-1, CITED-1 and FN-1 can be a useful tool for differentiation between benign and malignant follicular thyroid neoplasms and probable distinguishing of PTC from FTC.

[Aliaa Atef, and Mohammed Elrashidy. The application of Hector Battifora Mesothelial-1, CITED-1 and Fibronectin-1 in differential diagnosis of thyroid follicular neoplasms. Life Sci J 2016;13(2):78-84]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 13.

doi:10.7537/marslsj130216.13

Keywords: Papillary thyroid carcinoma, follicular thyroid carcinoma, HBME-1, CITED-1, FN-1

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Gamma radiosensitivity study on MRQ74 and MR269, two elite varieties of rice (Oryza Sativa L.)

Ahsan A. Kadhimi^1,3*; Arshad Naji ALhasnawi^1,4; Anizan Isahak²; Mehdi Farshad Ashraf¹; Azhar Mohamad⁵;.Wan Mohtar Wan Yusoff¹ AND Che Radziah Che Mohd Zain^1*

¹School of Biosciences & Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Malaysia

²School of Environmental Science and Natural Resources, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Malaysia

³University of Baghdad, Ministry of Higher Education, Iraq

⁴University Presidency, AL- Muthanna University, Iraq

⁵ Malaysian Nuclear Agency, Malaysia

*Correspondence email: kkkihsan@yahoo.com, cradziah@ukm.edu.my

Abstract: Gamma ray, a mutagen used in crop and ornamental plant breeding, is expected to induce novel mutations. Therefore, this study aimed to investigate the effect of different doses of gamma-ray (Caesium-137) irradiation on the germination rate, plant height, and appropriate dose for causing boom in two varieties of local rice, namely, MRQ74 and MR269. Dry MRQ74 and MR269 seeds were irradiated at 0, 100, 200, 300, 400, 500, 600, and 700 Gy. Hydroponic germination under controlled conditions followed. The germination rate and the height of the plantlets were investigated as morphological responses. Consequently, compared with the control samples, the plantlets that were given low doses (0 and 100 Gy) showed an increase in height, whereas those given doses ranging from 200 to 500 Gy showed a reduction in germination rate and height. At doses exceeding 500 Gy, physiological damage on the seedling height became severe and none of the varieties survived. Doses between 340 and 360 Gy caused a 40% reduction in seedling height in MR269 and MRQ74. Doses between 351 and 365 Gy caused a LD50 dose in MR269 and MRQ74, respectively.

[Ahsan A. Kadhimi; Arshad Naji ALhasnawi; Anizan Isahak; Mehdi Farshad Ashraf; Azhar Mohamad;Wan Mohtar Wan Yusoff AND Che Radziah Che Mohd Zain. Gamma radiosensitivity study on MRQ74 and MR269, two elite varieties of rice (Oryza Sativa L.). Life Sci J 2016;13(2):85-91]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 14.

doi:10.7537/marslsj130216.14

Keywords: Dose irradiation germination rate Reduction in seedling length Mutagenesis

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Effect of Licorice Extract against Gentamicin-Induced Nephrotoxicity in Male Rats

Fatimah M. Yousef ¹ and HudaM. Alkreathy²

¹Department of Food and Nutrition, Faculty of Home Economics, King Abdulaziz University, Jeddah, Saudi Arabia.

²Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Abstract: Background: Nephrotoxicity induced by several synthetic drugs represents a major problem of modern population. Licorice Glycyrrhiza glabra L.is one of the most widely used herbal drugs around the world, being present in most pharmacopoeias of eastern and western countries. It exhibits many biological activities and possibly even has protective effects against chronic diseases. Aim: The present study was conducted to determine the protective effect of licorice extract against gentamicin-induced nephrotoxicity in male rats. Material and Methods: Forty male rats were divided into four groups as follow; (1): control group, (2): gentamicin (GM) group; rats injected intraperitioneally (i.p.) with GM at a dose of 100 mg /kg body weight (b.w.) for five consecutive days to induced nephrotoxicity, (3): licorice extract group; rats administered licorice extract daily at a dose of 150 mg/ kg b. w. via gavage, and (4) GM group pretreated with licorice extract; rats were orally received licorice extract at the same dose and route in group (3) up to seven days followed by injected i.p. with GM as in group (2). Separated serum samples were used for determination of kidney functions and ionic sodium (Na⁺) and potassium (K⁺). One kidney was used for estimation of lipid peroxides (MDA) and reduced glutathione (GSH), while the other kidney was examined histopathological. Results: GM injection induced marked nephrotoxicity as evidenced by significant elevation in serum levels of creatinine, urea, uric acid and K⁺, with significant reduction in serum levels of Na⁺. Antioxidant status in kidney tissues showed that, in GM there was significant increase in MDA with significant depletion in GSH activity as compared with control group. Pretreatment with licorice extract protected the rats from GM- induced nephrotoxicity as evidenced by significant improvement of these investigated parameters, with restore antioxidant status. Histological examination of renal tissues showed marked glomerular, vacuolations of the wall of blood vessels associated with necrobiotic changes in renal tubules in GM injected group, meanwhile there were amelioration in rats group received licorice extract pre-GM injection. Conclusion: Licorice extract exert potential antioxidant activity and offer nephroprotective effect against GM- induced nephrotoxicity in male rats.

[Fatimah M. Yousef and Huda M. Alkreathy. Effect of Licorice Extract against Gentamicin-Induced Nephrotoxicity in Male Rats. Life Sci J 2016;13(2):92-100]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 15.

doi:10.7537/marslsj130216.15

Key words: Licorice extract, gentamicin, nephrotoxicity, antioxidant, rats

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Parametric Study of The Structural Behavior of Horizontally Curved Bridge Deck

Medhat Kamal Abdullah

Department of Civil Eng., Faculty of Engeneering, Helwan University, Cairo, Egypt.

infra@infraconsultants.org

Abstract: This paper investigates the impact of the following parameters on the structural behavior of horizontally curved bridge decks: 1- the analytical modeling methods; 2- the radius of curvature; 3- the number of internal cross girders and 4- the thickness of the deck slab. The results of the different analytical modeling technique are compared to experimental results by conducting a load test on a curved bridge deck physical model at the structural lab of the American University in Cairo. The remaining parameters of this study are investigated using a typical curved concrete slab-girder bridge deck which is commonly used in real projects. The impact of these parameters on the structural behavior of the deck is addressed by the change in straining actions and the deflection of the main girders of the bridges.

[Medhat Kamal Abdullah. Parametric Study of The Structural Behavior of Horizontally Curved Bridge Deck. Life Sci J 2016;13(2):101-111]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite.com. 16.

doi:10.7537/marslsj130216.16

Keywords: horizontallycurved bridge deck-cross girders- radius of curvature- bridge modeling-grillage analysis

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