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Retropubic Laparoscopic Prostatectomy: Initial Experience

Essam Raid, Samir Ghobashy, Ahmed Elbaz, Mamdouh Roshdy, Hossam El Ganzoury and Ahmed Kamal

Urology Departments, Theodor bilharz Research Institute, Cairo, Egypt

Elghobashys@yahoo.com

Abstract: Background: Benign prostatic hyperplasia (BPH) is one of the most common diseases in middle-aged and old males. Medical intervention is not effective in all cases and surgical prostatectomy is the curative treatment. Aim of the work: to presented our experience with retropubic laparoscopic simple prostatectomy. Patients and methods: This study was conducted on 33 patients with BPH who underwent laparoscopic retropubic simple prostatectomy between January 2012 and June 2014; they were selected from Urology Departments, Theodor bilharz Research Institute (urology department). Before the surgery, full history taking, physical examination, digital rectal examination (DRE), routine lab tests, IPSS, transrectal ultrasonography (TRUS), prostate-specific antigen (PSA) measurement, and uroflowmetric studies were performed. IPSS and uroflowmetry were performed again 2 months after the surgery for comparison with the preoperative data. To rule out cancer in patients whose PSA values were 4 and over or who had any other risk factor (nodule on the DRE or hypoechoic lesion on TRUS), prostate biopsy was performed before surgery. Results: Age ranged from 54 to 73 years with a mean of 60.82±4.02 years; the mean prostate volume was 92.66±11.48; while the mean enucleate volume was 73.57±7.44 g; mean operative time was 176.21±16.68 minutes; mean blood loss was of 350.30±73.50 cc; mean postoperative hospital stay was 6.42±1.06 days; drain removed in day 3 to 6 with mean of 4.36±0.78 and Foley urethral catheter duration was ranged from 4 to 8 days with a mean of 5.36±1.08 days. IPPS was significantly decreased from 26.77±2.06 preoperatively to 4.84±0.79 postoperatively (p < 0.001). Five cases were presented by acute urinary retention. Thus, Qmax was reported only for 28 cases preoperatively, the mean value was 5.63±1.34 that increased significantly at postoperative value to 16.94±2.27. Finally, post voiding residual urine was decreased significantly from 94.17±8.99 at preoperative evaluation to 16.06±5.53 at 2 months postoperative evaluation. Conclusion: laparoscopic retropubic simple prostatectomy may be a useful treatment option for patients with large volume BPH, especially with experienced hands.

[Essam Raid, Samir Ghobashy, Ahmed Elbaz, Mamdouh Roshdy, Hossam El Ganzoury and Ahmed Kamal Retropubic Laparoscopic Prostatectomy: Initial Experience. Life Sci J 2015;12(6):1-5]. (ISSN:1097-8135). http://www.lifesciencesite.com. 1. doi:10.7537/marslsj120615.01

Keywords: laparoscopic, prostatectomy

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Evaluation of the Role of Computer Tomography Virtual Cystoscopy in Diagnosis of Carcinoma of the Bladder

Rabab Shimy¹, Ahmed Mehena², Mohamed Wishahi², Hossam Elganzoury², Ahmed M. Kamal², Mohamed Badawy², Khaled Elesseily², Faten Kamel³, Susan Ali³, Lobna Habib³

¹Department of Radiology, Theodor Bilharz Research Institute, Cairo/Egypt

²Department of Urology, Theodor Bilharz Research Institute, Cairo/Egypt

³Department of Radiology, Faculty of Medicine, Ain Shams Unversity, Cairo/Egypt

moh.weshahy@gmail.com

Abstract: Objectives: To investigate the utility, advantages and limitations of computed topographic (CT) virtual cyctoscopy in the detection and diagnosis of bladder tumors in comparison to conventional cyctoscopy. Patients and methods: Fifty patients were included in our study, 39 of them presented with haematuria and a recent diagnosis of bladder carcinoma, and 11 patients with a history of previous transurethral resection of superficial bladder cancer in their follow up period. They ranged in age 42 years to 75 years with a mean of 58.5; while male to female ratio was 5.25:1.The main steps to perform virtual cyctoscopy incorporate proper bladder distention with air after draining the residual urine through Foley´s catheter and scanning the patient in both supine and prone positions. An excellent overview of the bladder masses was obtained in all cases and the results of virtual cyctoscopy and conventional one were comparable with excellent sensitivity rates of virtual cyctoscopy in detection, localization and morphology description of the bladder lesions at variable sizes. Results: For detection of all lesions (n=62), virtual cyctoscopy alone showed sensitivity :98.4%, specifity:81.81% with two false positive and one false negative in comparison to conventional cyctoscopy which detected 61 lesions while in axial CT alone the sensitivity was73.8%, and specifity 100%. Conclusion: CT virtual cystoscopy is a promising technique for use in bladder tumor detection of lesions larger than 5 mm. optimal evaluations requires adequate bladder distention with the patient in both supine and prone positions and interpretation of both transverse and virtual images.

[Rabab Shimy, Ahmed Mehena, Mohamed Wishahi, Hossam Elganzour, Ahmed M. Kamal, Mohamed Badawy, Khaled Elesseily, Faten Kamel, Susan Ali, Lobna Habib. Evaluation of the Role of Computer Tomography Virtual Cystoscopy in Diagnosis of Carcinoma of the Bladder. Life Sci J 2015;12(6):6-14]. (ISSN:1097-8135). http://www.lifesciencesite.com. 2. doi:10.7537/marslsj120615.02

Keywords: Virtual cyctoscopy, bladder tumor, computed tomography, cancer.

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Construction of a Novel Recombinant Adenovirus (Ad5-p53-DsRed Monomer N1)

Asita Elengoe, Salehhuddin Hamdan*

 Department of Biological Sciences, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia

asitaelengoe@yahoo.com, saleh65@utm.my*

Abstract: Oncolytic adenoviruses are a class of promising anti-cancer agents, which are engineered to infect, replicate within, and lyses cancer cells without damaging normal cells. In this study, we reported for first time the construction of adenovirus serotype 5 (Ad5) by cloning p53 gene into defective recombinant adenovirus vector containing red fluorescence protein (Ad5-p53-DsRed Monomer N1). This recombinant virus can be a potential anti-cancer agent in cancer treatment. Firstly, human tumor protein p53 gene (Entrez ID: 7157) was successfully cloned into pDsRed Monomer N1 vector. The size of the recombinant plasmid (p53-DsRed Monomer N1) obtained was approximately 5.9 kb. The p53-DsRed Monomer N1 construct was then used to insert into entry clone (pENTR3C^TM). The p53 gene was successfully cloned into the pAd/CMV/V5-DEST^TM vector through the entry clone (pENTR3C^TM). The size of PCR product of Ad5-p53-DsRed Monomer N1 was about 10.3 kb. Finally, Ad5-p53-DsRed Monomer N1 was transfected in Vero cells to determine expression of p53. The transfected cells presented diffuse red fluorescence from the DsRed Monomer N1 that appeared to be present throughout the cytoplasm and nucleus. The presence of DsRed Monomer N1 in cells was a strong indicator of transfection of the recombinant construct and thus possible p53 expression. This study reveals future perspective to develop a promising treatment for cancer patients.

[Elengoe A, Hamdan S. Construction of a Novel Recombinant Adenovirus (Ad5-p53-DsRed Monomer N1). Life Sci J 2015;12(6):15-28]. (ISSN:1097-8135). http://www.lifesciencesite.com. 3. doi:10.7537/marslsj120615.03

Keywords: Adenovirus, p53, pDsRed Monomer N1, Ad5-p53-DsRed Monomer N1

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Preventive Practices Adopted by Hepatitis "C" Patients in Alexandria-Egypt.

Faten Ezz El-Din Fikry, Hanan Hosni El-Sherbini and Asmaa Mohamed Saad

Community Health Nursing, Faculty of Nursing, Alexandria University, Egypt.

hsherbini@gmail.com

Abstract: Background: Hepatitis C viral infection is one of the most contagious diseases. It is approximately 10-15 times more infectious than HIV. Objective: the present study aimed to assess preventive practices adopted by hepatitis C patients in Alexandria and identify factors affecting their practices. Settings: The study was carried out at three outpatient hepatic clinics representing: Ministry of Health and Population (Shark El- Madina Hospital), Ministry of Higher Education (Main University Hospital) and Health Insurance Sector (Gamal Abdel-Nasser Hospital). Subjects: subjects of the study were 450 chronic hepatitis C adult patients of both sexes; a sample of 150 patients was selected from each of the above mentioned settings. Tools: One tool was used in this study (hepatitis C patient’s basic data and preventive practices structured interview schedule). Results: Findings of the present study revealed that more than three quarters (76.7%) of the patients had low preventive practices score regarding hepatitis C virus, 22.2% of them had moderate preventive practices score and only 1.1% of them had high preventive practices score. Patients’ age, sex, marital status, occupational status, monthly income and patients’ knowledge level had significant effect on their preventive practices. Conclusion: The study concluded that most of the studied patients had low level of preventive practices about hepatitis C infection.

[Faten Ezz El-Din Fikry, Hanan Hosni El-Sherbini and Asmaa Mohamed Saad. Preventive PracticesAdopted by Hepatitis "C" Patients in Alexandria-Egypt. Life Sci J 2015;12(6):29-41]. (ISSN:1097-8135). http://www.lifesciencesite.com. 4. doi:10.7537/marslsj120615.04

Key words: Hepatitis C, Preventive practices.

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Efficacy of Topical Hyaluronic acid during adjuvant Breast Cancer Radiotherapy for radiation dermatitis prophylaxis

Nehal Mohamed Elmashad ⁽¹⁾, Fatma Zakaria Hussen⁽¹⁾ and Rania Ahmed Eltatawy⁽²⁾

Department of Clinical Oncology ⁽¹⁾ and Dermatology and Venereology ⁽²⁾ Tanta University Hospital Tanta Faculty of Medicine, Tanta, Egypt

nehalelmashad@yahoo.com

Abstract: Purpose: To determine the efficacy of an emulsion containing hyaluronic acid to reduce the development of grade II or higher radiation dermatitis after adjuvant breast irradiation. Patients and methods: Two hundred and nine female patients with breast cancer who conducted to receive adjuvant breast irradiation distributed into two groups, Group I, the control group (n=80 patients) and Group II, the treated group (n=129 patients) with application of hyaluronic acid-based gel topical agent (Ialugen ® plus) 2 weeks before treatment course and then all- through radiation therapy period twice a day. All patients were followed during radiotherapy course and then 3 months later for the primary end point radio-dermatitis GII or higher according to (RTOG/EORTC Scale) and for the secondary end points pain, quality of life & treatment interruption. Univariate and multivariate analysis (ordered logistic regression) were considered. Results: Two hundred and nine female breast cancer patients aging 27-71 years, distributed into two groups, Group I (control group) n=80 patients (mean age= 48.7; SD= 10.845) and Group II (treated group) n=129 patients (mean age=50.95, SD= 10.369). Patients’ characteristics were matched for both groups except for Body mass index (BMI), Quality of life (QOL) and treatment Interruption with significant differences in expense of control group. For radio-dermatitis, over all incidence of skin toxicity was 61,7%, with more than 2\3 reduction in radio- dermatitis with treated group, radio -dermatitis grade II and higher was 41.3%, n=33 patients in control arm versus 10.1%, n=13 patients in treated group, p=<0.001. No patients presented with severe skin reaction (GIII&IV) in treated group. More than 10 times reduction in pain scores in treated versus control groups. Our data consolidated with spearman rho correlation coefficient test for radiation dermatitis and pain scores during radiotherapy course and 3 months later. Multivariate analysis as regard skin radiation toxicity at week 3 of radiation dermatitis showed that the only effective risk factors were interrupted treatment, p =0.00, OR=0.02, 95%CI (0.002-0.176), QOL, p =0.02, OR=11.82,95%CI (1.411-97.027), radiation dose, p =0.00, OR=0.78,95%CI (0.306-1.995) and boost dose, p =0.00, OR=0.27,95%CI (0.134-0.541). Conclusion: Application of hyaluronic acid-based gel (Ialugen ® plus) during adjuvant breast cancer radiotherapy has favorable impact on radio-dermatitis GII or higher, skin welfare, tolerability and treatment effectiveness.

[Nehal Mohamed Elmashad, Fatma Zakaria Hussen and Rania Ahmed Eltatawy. Efficacy of Topical Hyaluronic acid during adjuvant Breast Cancer Radiotherapy for radiation dermatitis prophylaxis. Life Sci J 2015;12(6):42-53]. (ISSN:1097-8135). http://www.lifesciencesite.com. 5. doi:10.7537/marslsj120615.05

Key words: hyaluronic acid, Breast cancer, adjuvant radiotherapy, radio-dermatitis, quality of life.

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Quality-of- life scores in locally advanced laryngeal carcinoma patients as a predictive value and impact on survival

Mohamed Shetaand Omnia Abd –El-Fattah

Department of Clinical Oncology, Tanta University Hospital, Tanta, Egypt

omniaabdelfattah@yahoo.com

Abstract: Purpose: Analysis thefactors that determine quality-of-life (QOL) scores among successfully treated locally advanced laryngeal squamous cell carcinoma patients and clarify their impact on survival. Patients and Methods: A study was conducted to determine the relationship between QOL scores (Physical and mental component of short form SF-36 questionnaire and the pain, eating, speech, and mood domains from University of Washington Quality of Life (UW-QOL) questionnaire and all-cause survival among 62 locally advanced laryngeal cancer patients. Results: The Physical and mental component of short form SF-36 Score and the pain, eating and mood domains from UW-QOL score were significant survival predictors. The speech domain of UW-QOL score was not associated with survival. Conclusion: QOL scores were valuable in predicting and detecting those patients with poor survival who had low score in order to improve survival by close follow up, early treatment of recurrence and any detected deterioration in one or more of QOL domain in those patients.

[Mohamed Shetaand Omnia Abd –El-Fattah. Quality-of- life scores in locally advanced laryngeal carcinoma patients as a predictive value and impact on survival. Life Sci J 2015;12(6):54-62]. (ISSN:1097-8135). http://www.lifesciencesite.com. 6. doi:10.7537/marslsj120615.06

Keywords: quality-of-life (QOL); laryngeal squamous cell; carcinoma; patient; survival

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Synthesis and Anticancer Activity of New Substituted Pyrimidines, Their Bicyclic and Thioglycoside Derivatives

W.A. El-Sayed,¹* I. F. Zeid,² E.M.H Morsi,¹ N. Tawfek,¹ N. M. Yousif,¹ S. Yahia,³ A. A.-H. Abdel-Rahman²*

¹Department of Photohemistry, National Research Centre, El Buhouth St., Dokki, Giza, Egypt.

²Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt

³Department of Biochemistry, National Research Centre, El Buhouth St., Dokki, Giza, Egypt *adelnassar63@yahoo.com, waelshendy@gmail.com;

Abstract. New aryl substituted pyrimidine, oxazole, oxathiolane and thiazolopyrimidine derivatives were synthesized. The glycoside and bicyclic condensed derivatives of the pyrimidine ring system were prepared. The anticancer activity of the prepared compounds against MCF-7 human breast cell line was studied and a number of compounds showed good activity.

[W.A. El-Sayed, I. F. Zeid, E.M.H Morsi, N. Tawfek, N. M. Yousif, S. Yahia, A. A.-H. Abdel-Rahman. Synthesis and Anticancer Activity of New Substituted Pyrimidines, Their Bicyclic and Thioglycoside Derivatives. Life Sci J 2015;12(6):63-70]. (ISSN:1097-8135). http://www.lifesciencesite.com. 7. doi:10.7537/marslsj120615.07

Keywords: Pyrimidines, Thiazolopyrimidines, Anticancer, Thioglycosides, MCF-7

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A High Gain Ultra Wideband Microstrip Antenna for EHF Medical Applications

Abdul Muqeet Mohammed, Adnan Affandi & Abdullah M. Dobaie

Dept., of Elect.& Comp. Eng., Faculty of Eng. King Abdul Aziz University Jeddah, KSA

abdulmuqeet.0431@gmail.com

Abstract: A simple high gain ultra-wideband Microstrip patch antenna for extremely high frequency applications (EHF) is proposed in this paper. The antenna has simple shape and small size enable it to be inserted inside any medical gadget operating in EHF frequency band. The antenna overall dimensions are 57.3×4×1.6 mm. Simulation results show that the antenna has a bandwidth of 31.39 GHz which support a very high data rates and a maximum gain of 11.53dBi which represents such a high gain that the antenna can be considered to be with negligible losses.

[Abdul Muqeet Mohammed, Adnan Affandi & Abdullah M. Dobaie. A High Gain Ultra Wideband Microstrip Antenna for EHF Medical Applications. Life Sci J 2015;12(6):71-73]. (ISSN:1097-8135). http://www.lifesciencesite.com. 8. doi:10.7537/marslsj120615.08

Keywords: Microstrip Antenna; Ultra-wideband; Antenna Gain; Return loss; Reflection Coefficient

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Simulation of Rayleigh channel and improve of channel estimation using Artificial Neural Network

M.A. Alamoudi & Adnan Affandi

Dept. of Elect. & Comp. Eng., Faculty of Eng., King Abdul Aziz University Jeddah, KSA

abasultan@yahoo.com

Abstract: A statistical characteristic of wireless channels is partially covered by the Rayleigh distribution. It best represents the condition where there are secondary reflections due to high rise structures are always threatening to degrade communication quality. An ANN can be used to provide an estimate of the channel to minimize some of the deficiencies of multi-user transmission under Rayleigh multipath fading. The ANN can be trained to tackle such fading and associated disturbance, channel estimation task is critical for coherent detection and demodulation, in this paper we will present simulation of Rayleigh channel fading by using Neural Network techniques as standard Back propagation (BP).

[M.A. Alamoudi & Adnan Affandi. A Simulation of Rayleigh channel and improve of channel estimation using Artificial Neural Network. Life Sci J 2015;12(6):74-77]. (ISSN:1097-8135). http://www.lifesciencesite.com. 9. doi:10.7537/marslsj120615.09

Keywords: Rayleigh channel, Neural Network, etc.

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Comparative Study of Air Permeability of Polyester/ Metallic Blended Woven Fabrics

Ghada Ahmad Mohamad

Dept. of Spinning Weaving and Knitting, Faculty of Applied Arts - Helwan University

E-mail: ghada7070@yahoo.com

Abstract: The air permeability of a fabric is a measure of how well it allows the passage of air through it. The ease or otherwise of passage of air is of importance for a number of fabric end uses such as industrial filters, tents, sailcloth’s, parachutes, raincoat materials, shirting’s, down proof fabrics and airbags. A total of twenty seven woven fabrics were produced in three different weave patterns (sateen8, 4/4 hopsack and Kautshok) from (100% polyester, 100% metallic and 50% polyester, 50% metallic (1 pick: 1 pick) weft blend, of three different weft set (22 picks/cm, 28 picks/cm, 34 picks/cm). The fabrics of satin 8 obtained the highest rates of air permeability at 22 picks/cm for 100% metallic weft. The fabrics produced from kautshok obtained the lowest rates of air permeability at 34 picks/cm for 100% polyester weft.

[Ghada Ahmad Mohamad. A Comparative Study of Air Permeability of Polyester/ Metallic Blended Woven Fabrics. Life Sci J 2015;12(6):78-82]. (ISSN:1097-8135). http://www.lifesciencesite.com. 10. doi:10.7537/marslsj120615.10

Key words: air permeability, polyester, metallic, woven fabrics.

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Biological Studies on Airborne Cladosporium Species Isolated from Riyadh City

Mohammed S. Alhussaini^1*, M.A. Moslem², Mohammed I. Alghonaim³, Abdullah A. Al-Ghanayem⁴ and Hamido M. Hefny⁵

^1,4,5,6Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Saudi Arabia.

²College of Science, Botany and Microbiology Department, King Saud University, Riyadh, Saudi Arabia

³Department of Biology, College of Science and humanities, Al-Quway’iyah, Shaqra University, Saudi Arabia.

malhussaini@su.edu.sa

Abstract: The biological studies were performed using five different Cladosporium species. The five fungal species were isolated during investigation of the geographical distribution of Cladosporium at Riyadh. The five fungal species were with the codes; Clad#4, Clad#5, Clad#8, Clad#12, and Clad#16). In order to investigate the effect of environmental and physiological factors on the mycelial growth of Cladosporium spp., the effect of temperature, pH, carbon and nitrogen sources, and different culture media on mycelial growth of Cladosporium species were studied in vitro. Analysis of variance (ANOVA) showed very highly significant (P = 0.0001) effects of Temperature, and significant effects of Temperature × isolate interaction on mycelial dry weight of Cladosporium. Analysis of variance of the effect of pH, Cladosporium isolate, and their interaction showed that they were all very highly significant sources of variation in mycelial dry weight of Cladosporium. Also, Carbon source, isolate, and Carbon source × isolate interaction were all very highly significant sources of variation in mycelial dry weight of Cladosporium. ANOVA showed very highly significant effects of Nitrogen source, isolate, and Nitrogen source × isolate interaction on mycelial dry weight of Cladosporium. Out of five solid media tested for their effect on mycelial growth, for most of Cladosporium species the maximum colony diameter was recorded on sabouraud dextrose agar medium followed by potato dextrose agar medium.

[Mohammed S. Alhussaini, M.A. Moslem, Mohammed I. Alghonaim, Abdullah A. Al-Ghanayem and Hamido M. Hefny. Biological Studies on Airborne Cladosporium Species Isolated from Riyadh City. Life Sci J 2015;12(6):83-91]. (ISSN:1097-8135). http://www.lifesciencesite.com. 11. doi:10.7537/marslsj120615.11

Keywords: Cladosporium genus, Cladosporium spices.

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Therapeutic role of ginger and chamomile aqueous extract for peptic ulcer using experimental rats.

El-Sayed H. Bakr^1,2 and Sameh M. Baz^3,4

¹Nutrition and Food Science Department, Faculty of Home Economics, Minufiya University, Egypt.

²Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah, KSA.

³Lab Medicine Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah, KSA.

⁴Clinical Pathology Department, Cairo University Hospital, Cairo, Egypt.

sayedhamed20007@hotmail.com, smszhnaalms9@hotmail.com

Abstract: This work was designated to clear out the effect of aqueaus extracts of ginger (Zingiber Officinale) family zingiberaceae and chamomile (Matricaria chamomilla) a member of Asteraceae family on healing aspirin induced ulcer in male albino rats. Thirty six male albino rats (150±10g b.wt. each) were used and disparted into 6 groups (n= 6 rats), one of them used as control-ve group while other 5 groups orally given aspirin (200mg/kg b.wt.), one of these groups left as control +ve and the rest groups orally administrated with aqueous extracts of ginger and chamomile at two doses of 200 and 400 mg/kg b.wt., for each of them for seven days. The length of gastric ulcer, the volume of gastric juice, pH, total acidity and histopathological changes were examined. The results concluded that oral administration with all doses of aqueous extracts of ginger and chamomile reduced the length of gastric ulcer, total acidity, volume of gastric juice and histopathological changes. On the other hand, all aqueous extracts increased pH value of gastric juice. According to the results, ginger and chamomile could be used for healing acute gastric ulcer disease especially ginger and chamomile water aqueous extract at doses of 400 mg/kg b.wt., for each of them.

[El-Sayed H. Bakrand Sameh M. Baz. Therapeutic role of ginger and chamomile aqueous extract for peptic ulcer using experimental rats. Life Sci J 2015;12(6):92-99]. (ISSN:1097-8135). http://www.lifesciencesite.com. 12. doi:10.7537/marslsj120615.12

Keywords: Peptic ulcer, aqueous extract, ginger, chamomile, histopathological changes.

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Improvement of marketing management of enterprises

Fikret Veli Guliyev ¹

^1. Azerbaijan Cooperation University, Candidate of Economic Sciences, Baku, Azerbaijan

Abstract: When enterprises rely on their prouction capacity and produce goods without learning the needs and tastes of consumers and present them to the market, difficulties arise in the sale and their market situation gradually gets worse. In order to prevent such situation and ensure success in market activities it is necessary to follow the system of marketing management of enterprise activities.

[Guliyev FV. Improvement of marketing management of enterprises. Life Sci J 2015;12(6):100-104]. (ISSN:1097-8135). http://www.lifesciencesite.com. 13. doi:10.7537/marslsj120615.13

Keywords: Market orientation of enterprises; systematic approach; marketing service; marketing management; elements of the marketing system; organizational culture of marketing; contrary information contact; market subjects

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Exposure to Passive Smoking during Pregnancy and Its Adverse Effects on Pregnancy, and Neonatal Outcomes in Sohag Public Hospital

Thoria Mohamed Mohmoud¹, Nour El-Houda Moustafa², and Amina Mohamed Thabet³

¹ Community Health Nursing Department, Faculty of Nursing, Sohag University, Sohag, Egypt

² Obstetric and Gynecological Nursing Department, Faculty of Nursing, Sohag University, Sohag, Egypt

³Pediatric Nursing, Department, Faculty of Nursing, Sohag University, Sohag, Egypt

Abstract: Passive smoking during pregnancy doubles the risk of having a low-birth weight and small for gestational age infants and significantly increases the rate of perinatal morbidity and several other adverse pregnancy and neonatal outcomes. The aim of this study was to assess the effects of exposure to passive smoking during pregnancy on pregnancy and neonatal outcomes. A cross-sectional study design was selected to collect the data in the postpartum ward (delivery and postpartum room) of Sohag public Hospital- Sohag City. The sample included 300 neonates and their mothers (over a sex month's period from January to June 2014). A questionnaire sheet were designed by the researchers according to literature review was used to collect the necessary data. The main results in this study were (32.3%) of the mothers who exposed to passive smoking had placenta previa and abrupt placenta, (34.3%) of them had premature rupture of membrane, (48.3%) were caesarean section delivery, also (24.0%) of the mothers had premature infants, (37.0%) of newborns were less than 7 APGAR score at 1 minute, and (19.3 %) had respiratory distress. The study concluded that, passive smoker's pregnant women are exposed to many negative adverse effects on their pregnancy and newborns outcomes. Based on the study results it was recommended that obstetric and pediatric nurses should educate the new, prospective parents and pregnant women about the risks of exposure to passive smoking during pregnancy.

[Thoria Mohamed Mohmoud, Nour El-Houda Moustafa and Amina Mohamed Thabet. Exposure to Passive Smoking during Pregnancy and Its Adverse Effects on Pregnancy, and Neonatal Outcomes in Sohag PublicHospital. Life Sci J 2015;12(6):105-112]. (ISSN:1097-8135). http://www.lifesciencesite.com. 14. doi:10.7537/marslsj120615.14

Key words: passive smoking, pregnancy, postpartum and newborn outcomes.

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An Analysis of the Defects of Therapeutic Communication between Nurses and Patients in a Hospital: The Case of RSUD Prof. DR. W. Z. Johannes Kupang

Maria Yulita Nara, Atwar bajari

Faculty of Communication Studies, Universitas Padjadjaran, 2013 Bandung, Indonesia, Jl. Raya Bandung-Sumedang Km 21, Telp: (022) 7794126/7, Fax: (022) 87920376, Jatinangor-Sumedang 45363, Email: atwartwa@gmail.com

Abstract: This study focuses on the therapeutic communication between nurses and patients, based on the negative perceptions harbored towards poor patients who seek medical attention in a hospital. This research also focuses on how therapeutic communication occurs between nurses and patients in a Class III room and Pavilion room of RSUD Prof. DR. W. Z. Johannes Kupang. This research aims to (1) analyze communication types between the nurses and patients in the Class III room and Pavilion room of RSUD Prof. DR. W. Z. Johannes Kupang, (2) examine factors that shape the communication types, and (3) determine the interrelationships between the components of communication. The method used in this research was the qualitative with the approach to communication ethnographic study. The data collection techniques included participative observation, in-depth interview and documents analysis. The data was verified using triangulation. The findings of this research show that: (1) there were two types of communication in the therapeutic process between the nurses and patients in the Class III room and Pavilion room. The two types were communication between nurses and patients and communication between nurses and patient’s families. These two types of communication were the most significant occurrences, and (2) the components forming the communication were setting and scene related with space, time, situation, and psychological aspect; participants, consisted of main participants who are the nurses and patients, and supporting participants, i.e the patient’s families and doctors. Ends, which is related to the purpose of communication which is to achieve patient’s recovery; act sequences, related to the form and content of communication and the sequence of speech; key, related to the tone of voice in communication; instrumental, related to the channel and media used in communication; norms, related to the norms of interaction in the communication occurrences; and genre, related to the form of delivery, i.e. request, question, statement, advice, and notification; (3) Finally, these components were assessed on therapeutic communication of nurses to patients.

[Maria Yulita Nara, Atwar bajari. An Analysis of the Defects of Therapeutic Communication between Nurses and Patients in a Hospital: The Case of RSUD Prof. DR. W. Z. Johannes Kupang. Life Sci J 2015;12(6):113-120]. (ISSN:1097-8135). http://www.lifesciencesite.com. 15. doi:10.7537/marslsj120615.15

Keywords: Nurses-patients communication, Therapeutic Communication, Communication Ethnography

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A Cluster based Multipath Routing Scheme for Power Efficiency in Wireless Sensor Networks

¹A.P. Sridevi and ²Dr.A. Rajaram

¹Assistant Professor, LRG Government Arts College for Women, Tirupur

² Associate Professor, Department of ECE, Jayaram College of Engineering and Technology, Thuraiyur, India.

Abstract - Wireless sensor networks consist of some nodes that have limited processing capability, small memory and low energy source. These nodes are deployed randomly and often densely in the environment. In monitoring applications, sensor nodes sense data from the environment periodically and then transmit them to a base station which is called sink node. Thereby data transmission consumes node’s energy based on transmission distance. In most wireless sensor networks, the energy source of the node is limited and cannot be minimized. Here, we have proposed the cluster based multipath routing scheme for power efficiency for minimizing the power consumption in WSNs. It consists of three phases. These phases are the cluster topology and selection of cluster head, energy based multipath route and Power utilization procedure. The proposed scheme attains the balance between power efficiency, load balancing and network lifetime in WSNs. By simulation results, the proposed CMRP achieves better data delivery ratio, improved network lifetime, less end to delay and energy consumption in terms of mobility, time, throughput, packet interval and number of nodes than EEMCRP and FAF-EBRP.

[A.P. Sridevi and A. Rajaram. A Cluster based Multipath Routing Scheme for Power Efficiency in Wireless Sensor Networks. Life Sci J 2015;12(6):121-128]. (ISSN:1097-8135). http://www.lifesciencesite.com. 16. doi:10.7537/marslsj120615.16

Keywords: WSN, EEMCRP, Multipath routing, optimum energy path, network lifetime, end to end delay, energy consumption, throughput and delivery ratio

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Using Siro FAST System to Measure Handle Properties of Outerwear Woven from monofilaments Polyester yarn

Nagwa Ali AbouNassif

Fashion Design Department, Design and Art College, King Abdul Aziz University, Jeddah, kingdom of Saudi Arabia

dr.ngaa@hotmail.com

Abstract: Fabric hand attributes can be obtained through subjective assessment or objective measurements. In this study, handle of outerwear woven from monofilaments polyester yarn was obtained objectively using FAST evaluation system. The effect of weave factor and weft yarn density were intended to be studied on extensibility, formability, compressibility, and bending and shear rigidities of such fabrics. The experimental results were assessed using Two –way analysis of variance (ANOVA) in order to detect the significance influence of both independent variables on fabric properties at 0.05 and 0.01 significant levels. The findings of this paper showed that both variables, i.e. weave factor and weft density were found to have a profound impact on the most of fabric handle properties.

[Nagwa Ali AbouNassif. Using Siro FAST System to Measure Handle Properties of Outerwear Woven from monofilaments Polyester yarn. Life Sci J 2015;12(6):129-134]. (ISSN:1097-8135). http://www.lifesciencesite.com. 17. doi:10.7537/marslsj120615.17

Key Words: Siro Fast, Outerwear, polyester, monofilaments, weave factor, weft density, woven fabrics, shear rigidity.

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Value of (¹⁸F)-FDG PET/CT Scan as a New Imaging in Tumour Staging and Therapy Monitoring of Lymphoma

Nadia AbdElsater Metwally¹, Hoda Mahmoud Abd Elwahab¹ and Noha Abd Elshafy Al Said²

¹Radiodiagnosis Departments, Faculty of Medicine (For Girls), Al-Azhar University, Cairo, Egypt

²National Cancer Institute, Cairo University^, Cairo, Egypt

Dr.hani.hammam@gmail.com, hodawaleed@hotmail.com

Abstract: Background: The purpose of this study was to highlight the advantages and pitfalls of combined (¹⁸F)-FDG PET/CT scanning in diagnosis and follow up of lymphoma. Patients and Methods: (40) patients who clinically diagnosed as lymphoma underwent (¹⁸F) FDG PET/CT scan in the radiology department between the year (2011-2012) for staging and therapy assessment. Results: Positron emission tomography (PET) with glucose analog fluorine 18 (fluorodexoglucose) (¹⁸F FDG) is increasingly recognized as a powerful evaluation imaging modality in lymphoma. It enables detection of increased glucose metabolic rate that is characteristic of most malignant cells. Useful for initial diagnosis, staging, recurrence and evaluation of therapeutic response. Conclusion: Combined (¹⁸F) FDG PET/CT proved more accurate diagnostic modility than CT because of its ability to differentiate viable tumour from post therapy necrosis or fibrosis. Also depict residual mass in patients without clinical orbiochemical evidence of the disease. Therefore it is a noninvasive modality of choice for lymphoma classification.

[Nadia Abd Elsater Metwally, Hoda Mahmoud Abd Elwahab and Noha Abd Elshafy Al Said. Value of (¹⁸F)-FDG PET/CT Scan as a New Imaging in Tumour Staging and Therapy Monitoring of Lymphoma. Life Sci J 2015;12(6):135-148]. (ISSN:1097-8135). http://www.lifesciencesite.com. 18. doi:10.7537/marslsj120615.18

Keywords: (¹⁸F)-FDG PET/CT Scana, Lymphoma staging, Lymphoma therapy

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Relationship Between Religious Practices and Academic Achievement

of Muslim Convert Students in Malaysia

Razaleigh Muhamat Kawangit¹, Marlon Pontino Guleng²

[1] Department of Da’wah and Leadership Studies, Faculty of Islamic Studies, National University of Malaysia, 43600, Bangi, Selangor, Malaysia

2 Department of Da’wah and Management, International Islamic University College, Selangor, Malaysia

raza@ukm.edu.my

Abstract: This study aimed to identify the relationship of religious practices and its relationship to academic achievement of Muslim convert students in Malaysia by representing students from Malaysian Institute of Islamic Da'wah (MIID). A total of 200 students in MIID were randomly selected for this study. The findings of the descriptive analysis showed that overall faith and worship practices of the Muslim convert students have a lower mean level of faith (2:59) and religious (2.66), while the morals of students have a moderate level of mean (3.18). The results of Pearson correlation analysis showed a significant relationship between religious faith practices (r = .731, p <0.01), worship (r = .737, p <0.01), and morals (r = .691, p <0.01) with the academic achievement of Muslim convert students.

[Razaleigh Muhamat Kawangit, Marlon Pontino Guleng. Relationship Between Religious Practices and Academic Achievement of Muslim Convert Students in Malaysia. Life Sci J 2015;12(6):149-154]. (ISSN:1097-8135). http://www.lifesciencesite.com. 19. doi:10.7537/marslsj120615.19

Keywords: Religious Practice, Faith, Worship, Morals, Academic Achievement

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Effect of vitamin D on Hepcidin Level and anemia in chronic kidney Disease

Ashraf kotb abdellatief¹, Abdo M.A. Ibrahim², Almotaz Hashim³, Mohamed Farouk Sayed⁴

¹Department of Physiology, Faculty of Medicine, Baterjee Medical College

²Department of Physiology, Faculty of Medicine, Zagazig University and University of Jeddah, KSA.

³Department of Internal Medicine, Faculty of Medicine, Menoufia University and University of Jeddah, KSA.

⁴Department of Pharmacology, Faculty of Medicine, University of Jeddah, KSA.

drashrafsalem@hotmail.com

Abstract: Introduction: Hepcidin, a small peptide produced by the liver, is a recently discovered key regulator of iron homeostasis. Via the regulation of ferroportin, hepcidin inhibits intestinal iron absorption and iron release from macrophages and hepatocytes thus prevents the normal recycling of iron needed to support erythropoesis.Hepcidin levels are increased in cases of chronic kidney diseases. Vitamin D insufficiency is highly prevalent in chronic kidney diseases and is associated with erythropoietin hyporesponsiveness. Data suggest that for a proper response to the treatment of anemia, the body must somehow reduce hepcidin in order to increase iron that is needed for red cell production. Many studies suggest vitamin D to affect hepcidin level and thus make iron more available and help to correct anemia in chronic kidney disease. Objectives: This study aims to assess the effect of vitamin D on hepcidin level and hence, hemoglobin level, and iron status in chronic kidney disease. Methods: -thirty patients were included in this study twenty of which were having ESRD, and were on regular hemodialysis three times per week each session four hours, while the other ten were normal subjects. They were divided into three groups each contained ten persons. Group one: control group. Group two:Renal failure group Group three:Renal failure group treated with calcitriol which is an active form of vitamin D3 at a dose of 15micro gram/day (600 IU/day) for three months At the beginning of the study samples of blood were taken from patients of group two and three to measure urea and creatinine to detect the existence of renal failure. At the end of the study samples of blood were taken from all groups to measure the hemoglobin level, Hepcidin level, serum iron.serum ferritin, serum urea, serum creatinine, and total iron binding capacity. Results: The results showed that patients of group two having ESRD have chronic anemia, they recorded significantly less iron level and thus hemoglobin level compared to patients of the control group. This may be due to increased level of serum hepcidin in response to the chronic inflammatory state.The study also showed that ESRD patients in group two on regular hemodialysis had non significant increase in hepcidin level compared to control group this might be due to the negative feedback mechanism on hepcidin secretion at the liver, and the efficiency of dialysis which eliminates hepcidin. The study also showed that vitamin D may affect the hepcidin level significantly as group three the ESRD group given vitamin D showed significantly less hepcidin level compared to the ESRD group not given vitamin D.The ESRD group given vitamin D also recorded significant increase in the hemoglobin and iron levels compared to group two. Conclusion: it may be of benefit to give the chronic kidney disease patients vitamin D as it may affecthepcidin level and thus make iron more available and help to correct anemia.

[Ashraf kotb abdellatief, Abdo M. Ibrahim, Almotaz Hashim and Mohamed Farouk sayyed. Effect of vitamin D on Hepcidin Level and anemia in chronic kidney Disease. Life Sci J 2015;12(6):155-160]. (ISSN:1097-8135). http://www.lifesciencesite.com. 20. doi:10.7537/marslsj120615.20

Keywords: ESRD---End stage renal disease, GFR ---Glomerular filtration rate, CKD---Chronic kidney disease, EPO---Erythropoietin hormone

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Synthesis, Characterization, and Application of Dendrimer Modified Magnetite Nanoparticles as Antimicrobial Agent

Samia M. El-Sigeny¹, Manal F. Abou Taleb²

¹Department of Chemistry, Faculty of Science, Kafr El-Sheikh University, 33516 Kafr El - Sheikh, Egypt

²Polymer Chemistry Department, National Center for Radiation Research and Technology, P. O. Box No. 29, Nasr city, Cairo, 11731 Egypt

shelsigeny@yahoo.com.hk

Abstract:Synthesis and characterization of different generations (G₀–G₅) of polyamidoamine (PAMAM) dendrimer – coated Fe₃O₄ nanoparticles using ethyl acrylate and 1,3-propane diamine have been reported in this study. Superparamagnetic iron oxide Fe₃O₄ nanoparticles were synthesized by co- precipitation method and modified with tris(hydroxymethylamino) methane hydrochloride for dendrimer coating. Physical characterization of the newly prepared PAMAM dendirmer-coated Fe₃O₄ nanocomposite have been carried out by using infrared spectrophotometer (IR), Transmission electron microscope (TEM), steady-state spectrophotomer (UV–Vis), thermogravimetric analysis (TGA), and X–ray diffraction. TEM images demonstrated that the PAMAM dendirmer-coated nanocomposite have monodisperse of 7.3–6.3 nm. The antimicrobial activity of the PAMAM dendirmer-coated Fe₃O₄ nanoparticles and Fe₃O₄ nanoparticles were tested against various microorganisms Staphylococcus aureus (+ve) Gram and (-ve) Escherichia coli bacteria. In general, the PAMAMdendirmer -coated Fe₃O₄ nanoparticles showed good antimicrobial activity.

[Samia M. El-Sigeny, Manal F. AbouTaleb. Synthesis, Characterization, and Application of Dendrimer Modified Magnetite Nanoparticles as Antimicrobial Agent. Life Sci J 2015;12(6):161-170]. (ISSN:1097-8135). http://www.lifesciencesite.com. 21. doi:10.7537/marslsj120615.21

Keywords: Dendirmer; Magnetic nanoparticles; Iron oxide; Antimicrobial activity

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Voiding Functions: The effect of TVT and TOT

Amgad Abou-Gamrah, Wessam Abuelghar, Hazem Sammour and Mouhamed Abbas

Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Egypt.

migoa1@hotmail.com

Abstract: Objective: To analyze the symptoms of voiding dysfunction and urodynamic changes subsequent to placing tension- free vaginal tape or transobturator tape. Patients and Methods: A retrospective cohort study that included women with urodynamic stress urinary incontinence, in whom we placed tension-free tapes and conducted a urodynamic study one year later. The study included 90 women: 37 had tension-free vaginal tape and 53 had transobturator tape and was carried out between January 2009 and August 2010. The means of the preoperative and postoperative urodynamic parameters were analyzed. Results: We noted an average decrease in the maximum flow rate of 9ml/sec in the tension-free vaginal tape group (P = 0.002) and 3 ml /sec in the transobturator tape group (P < 0.001). For the tension-free vaginal tape group, we noted an increase in maximum closure pressure of 21cm H2O (P=0.004), an increase in maximum urethral closure pressure on stress of 11 cm H2O (P = 0.041) and 30% increase in pressure transmission ratio (P<0.001). Conclusion: The most consistent change after minimally invasive surgeries for urodynamic stress incontinence was the decrease in maximum flow rate following TVT.

[Amgad Abou-Gamrah, Wessam Abuelghar, Hazem Sammour and Mouhamed Abbas. Voiding Functions: The effect of TVT and TOT. Life Sci J 2015;12(6):171-174]. (ISSN:1097-8135). http://www.lifesciencesite.com. 22. doi:10.7537/marslsj120615.22

Key Words: Stress urinary incontinence, suburethral tape, tension-free vaginal tape, transobturator tape, urodynamic

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The Bishop Frame of Bezier Curves

Hatice Kusak Samanci, Serkan Celik, Muhsin İncesu

Department of Mathematic, Bitlis Eren University, Bitlis 13000, Turkey
hkusak@beu.edu.tr

Abstract: The purpose of this study is to discuss some differential geometric properties and Bishop frames of Bezier curves. Firstly, we investigate Frenet frame and contact theory of Bezier curves. Furthermore, we have given some necessary conditions and properties for the Bezier curve. Secondly we obtain the Bishop frame of Bezier curves in Euclidean 3-space.
[Kusak Samancı, H., Celik S., İncesu M. The Bishop Frame of Bezier Curves. Life Sci J 2015;12(6):175-180]. (ISSN:1097-8135). http://www.lifesciencesite.com. 23. doi:10.7537/marslsj120615.23

Keywords: Bezier Curves; Bishop Frames; Serret- Frenet Frames

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Adjustable Gastric Banding for Morbid Obesity: Radiographic Assessment, Preoperative Findings and Complications

S. Alyafei¹, Mohamed M Abuzaid², W. Elshami² and Fatima Hamad²

¹Radiography and Medical Imaging Department, Fatima College of Health Sciences, United Arab Emirates.

²Medical Diagnostic Imaging Department, University of Sharjah, United Arab Emirates.

Corresponding author: mohdfatah76@gmail.com

Abstract: Purpose: The purpose of this study was to determine the role of radiology in assessing patients, who had undergone adjustable gastric banding (AGB) procedures for the treatment of morbid obesity, and to find out the type and prevalence of pre-operative findings as well as to evaluate the frequency and type of postoperative complications. Material and Methods: Sixty-one patients (29 men, 34 women; mean age, 36.5 years; age range, 20-53 years) with morbid obesity (ranged from 35.7 to 66.1 kg/m²; mean body mass index, 50.9 kg/m²) underwent AGB surgeries. In all patients, radiographic Gastrografin Swallow examinations were performed preoperatively to eliminate any AGB surgery contraindications such as ulcerations, hiatus hernias, narrowing, obstruction and achalasia, and one day post-surgery to eliminate leakages and stenosis. All patients underwent another examination at one month, two months and three months postoperatively and whenever a complication is suspected or if there is insufficient weight loss (i.e. less than 5 kg/month) for adjustment of the gastric band diameter. Results: 60 patients underwent the procedure via laparoscope, and 1 patient via open surgery. The most common preoperative findings were gastroesophageal reflux (84.1%) and mucosal hypertrophy (25%). No perforations were found at one-day post-operations. Late postoperative complications occurred in 9.8% of patients and included stenosis, infection, port malposition and bolus impaction. Conclusion: Radiographic assessments play a key role in the pre-operative screening of AGB patients. It also plays a significant role in the detection of postoperative complications and managements of weight loss.

[S. Alyafei, Mohamed M Abuzaid, W. Elshami and Fatima Hamad. Adjustable Gastric Banding for Morbid Obesity: Radiographic Assessment, Preoperative Findings and Complications. Life Sci J 2015;12(6):181-185]. (ISSN:1097-8135). http://www.lifesciencesite.com. 24. doi:10.7537/marslsj120615.24

Keywords: Adjustable Gastric Banding, Morbid Obesity, Gastrografin, Radiography

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Chronic Hepatitis C Virus Infection and B-cell clonality

Marwa I. Abdelgawad¹_, Ebtesam M. El Gezawy ² and Hanan Sharaf El-Deen Mohammed³

¹Clinical Oncology Department, ²Clinical Pathology Department, ³Internal Medicine Department, Faculty of Medicine, Assiut University

Abstract: Background and Aim: An association between non-Hodgkin`s lymphoma (NHL) and hepatitis C virus (HCV) has been evidenced since few years. Expansions of B-cell clonality have been detected in peripheral blood and bone marrow in HCV patients. Lymphoid aggregates are found in the liver of chronically HCV-infected patients. Studying the nature of the aggregates in the molecular level is a guide to find out the prevalence of B-cell clonality. In this work we aimed to study B-cell infiltration of the liver and type of expansion whether monoclonal or polyclonal in chronically HCV patients and factors affecting it. Subjects and Methods: Liver biopsies of 120 patients with chronic hepatitis C viral infection were examined for presence of lymphoid aggregation. Clonality of lymphoid B-cells tested by polymerase chain reaction (PCR) to identify immunoglobulin heavy chain gene (IgH) rearrangements. The product is monoclonal if only one discrete band was detected. The correlation between clonality on one side and HCV RNA viral load, stage of fibrosis, grade of inflammation, levels of transaminases, alpha fetoprotein (AFP) and lactic dehydrogenase (LDH) was studied. Results: Sixteen patients (13.33%) expressed monoclonal B-lymphocytic (MBL) expansion and 18 patients (15%) showed polyclonal B-lymphocytosis (PCBL). No significant difference in the stage of fibrosis, the degree of inflammation and AFP levels between MBL positive and negative groups was detected in the current study. MBL positive patients had significant much higher viral load (p=0.0001), AST(p =0.0001), ALT(p =0.006) and LDH(p =0.04) compared to MBL negative ones. On the other hand positive polyclonal B-lymphocytes (PCBL) had significant higher stage of fibrosis (p =0.011), grade of inflammation (p =0.026) and liver enzymes; AST and ALT (p =0.0001 for each) serum LDH (p =0.016) and lower viral load (p =0.0001) compared to negative PCBL patients, but no significant difference between PCBL positive patients and PCBL negative patient regarding AFP levels. Correlation between occurrence of clonal IgH with laboratory variables revealed significant positive correlation between the occurrence of clonal IgH and liver enzymes (AST, ALT), LDH, fibrotic stage and grade of inflammation. Conclusion: B-lymphocytic infiltration of the liver occurs in 28.3% in HCV chronically infected patients. We can expect lymphoproliferative infilteration in the liver using noninvasive laboratory investigation as AST, ALT and LDH. We could not depend on viral load to predict lymphoproliferative infilteration in the liver. Rearrangements of clonal IgH have significant positive correlation with liver enzymes (AST, ALT), LDH, fibrotic stage and grade of inflammation this suggest that these markers provides a convenient way to study the early stages of neoplastic transformation.

[Marwa I. Abdelgawad_, Ebtesam M. El Gezawy and Hanan Sharaf El-Deen Mohammed. Chronic Hepatitis C Virus Infection and B-cell clonality. Life Sci J 2015;12(6):186-192]. (ISSN:1097-8135). http://www.lifesciencesite.com. 25. doi:10.7537/marslsj120615.25

Keywords: Hepatitis C virus, B-cell clonality, Immunoglobulin heavy chain gene

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Production of high nutritive value and physical and sensory characteristic wheat biscuits fortified with chick pea flour

Hanan M.K.E. Youssef

Home Economic Department, Faculty of Specific Education, Ain Shams University, Cairo, Egypt

hanankamaly@yahoo.com

Abstract: Chick pea is reckoned as a valuable nutritional healthful functional food. The present investigation was performed to assess nutritional status of wheat biscuits and chick pea flour fortified wheat biscuits. Study included determination of gross chemical composition, caloric value, minerals (Mn, Ca, Fe, Cu, P, Na and K), vitamins (C, Folic acid, A, and E), and amino acid composition of wheat biscuits and 15%, 25% chick pea flour fortified wheat biscuits. Likewise, physical and sensory characteristics of studied biscuits were assessed. The data revealed that 25% chick pea flour fortified wheat biscuits proved to be nutritious functional healthful food. It improved both physical, sensory characteristics and increased protein and ash contents, but decreased fat, carbohydrates and caloric value. While, it recorded an increment in the all seven studied minerals as well as increased all the studied four vitamins, and the amino acids isoleucine, leucine, lysine, threonine, and valine contents resulting in an improvement of the nutritive value of 25% chick pea flour fortified wheat biscuits. Therefore it could be recommended for caloric reduced diets for diabetic, obese, and overweight persons, as well as for school students diets. Beside, it should be used as an ingredient in the bakery industry, i.e. in biscuits, bread, snack foods, breakfast foods, and cakes.

[Hanan M.K.E. Youssef. Production of high nutritive value and physical and sensory characteristic wheat biscuits fortified with chick pea flour. Life Sci J 2015;12(6):193-199]. (ISSN:1097-8135). http://www.lifesciencesite.com. 26. doi:10.7537/marslsj120615.26

Keywords: Wheat biscuits, 15%, 25% chick pea fortified biscuits, gross chemical composition, minerals, vitamins, amino acids, caloric value, physical, sensory characteristics.

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Mean platelet volume as a novel surrogate marker for early Non-Alcoholic Fatty Liver Disease

Walid Shehab-Eldin¹, Alaa Efat¹, Somaia Shehabeldeen², Abdallah Essa², Mohamed Shereef Abdou³, Hazem Omar⁴ and Dena Elazab⁵

¹Internal Medicine Department, Faculty of Medicine, Menoufia University, Egypt

²Gastroenterology Department, Faculty of Medicine, Menoufia University, Egypt

³Clinical Pathology Department, National Liver Institute, Menoufia University, Egypt

⁴Radiology Department, National Liver Institute, Menoufia University, Egypt

⁵Pathology Department, National Liver Institute, Menoufia University, Egypt

waleedshehab2000@gmail.com.

Abstract: Background: Non Alcoholic Fatty Liver Disease (NAFLD) is a chronic symptomless disease with deleterious outcome. The gold standard method of its diagnosis is liver biopsy (LB). LB, however, is invasive and not safe. Aim of the work: Prediction of early NAFLD. Subjects and methods:38 (24 males, 14 famales) volunteers assigned to liver donation were included in the study. Ultrasonography and LB were done during their routine pre-donation workup. Subjects were divided into 2 groups according to LB; control and NAFLD groups. All subjects underwent physical examination and anthropometric measures. Multiple indicators of NAFLD were assessed including blood glucose, lipid profile, and liver function tests. In addition Mean Platelet Volume (MPV) was assessed during routine CBC. Results: In a univariate logistic regression analysis waist circumference, leucocytic count, cholesterol, ALT and MPV were associated with NAFLD. In a multivariate regression analysis, only MPV was significant (p=0.017). ROC curve analysis detected MPV of 10.8 fl as the best cutoff level to predict NAFLD with sensitivity of 87%, specificity of 80% and AUC of 0.864. No significant difference was found between MPV and ultrasonography ROC curves to diagnose NAFLD (p=0.546). In Conclusion: MPV is an independent surrogate marker for the detection of early NAFLD.

[Walid Shehab-Eldin, Alaa Efat, Somaia Shehabeldeen, Abdallah Essa, Mohamed Shereef Abdou, Hazem Omar and Dena Elazab. Mean platelet volume as a novel surrogate marker for early Non-Alcoholic Fatty Liver Disease. Life Sci J 2015;12(6):200-205]. (ISSN:1097-8135). http://www.lifesciencesite.com. 27. doi:10.7537/marslsj120615.27

Key Words: Non-Alcoholic Fatty Liver Disease, Mean platelet volume and Surrogate marker.

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Outcomes of Foot Reflexology on the Pain and Certain Features of the Labor for the Primiparous Women

¹Hanan Abd ElFattah, ¹Sabah Metwaly and ²Nahed Khedr

¹Maternity and Neonatal Health Nursing Department, Faculty of Nursing, Ain Shams University

²Department of Woman Health Nursing and Midwifery Department, Faculty of Nursing, Mansoura University

h.mahgoub@mu.edu.sa

Abstract: Labor management should focus on the goal of delivering a healthy newborn while minimizing discomfort and complications for the mother. Reflexology is a noninvasive and non-pharmacological method of pain relief. The aim of this study is to evaluate the effect of foot reflexology on the pain and outcomes of labor for the primiparous women. A quasi-experimental research design was utilized in this study. A total of 120 primiparous women were selected by random sampling from Ain Shams University Maternity Hospital. They are divided into two equal study and control groups. Structured interviewing questionnaire, women assessment sheet (Partograph), Numerical Pain Rating Scale, and Satisfaction Rating Scale were utilized to collect data in this study. The result of this study revealed a statistical significant difference between study and control groups regarding mean labour pain score at cervical dilatation 6-8, 9-10 cm, and during third stage of labour. Also, revealed a statistical significant difference between them regarding frequency, duration and intensity of uterine contraction. In addition to shorter duration of the three stages of labour and lesser complication among women in the study group. The study provided evidence that foot reflexology could improve labour outcomes, and decrease complications, and recommended the use of foot reflexology as a non-pharmacological pain relief measures.

[Hanan Abd ElFattah, Sabah Metwaly and Nahed Khedr. Outcomes of Foot Reflexology on the Pain and Certain Features of the Labor for the Primiparous Women. Life Sci J 2015;12(6):206-216]. (ISSN:1097-8135). http://www.lifesciencesite.com. 28. doi:10.7537/marslsj120615.28

Keywords: Reflexology, labor pain, primiparous

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