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The effect of oral N-acetylcysteine on serum creatinine in chronic kidney diseases patients under CABG surgery

Mehdi Dehghani Firoozabadi ¹, Ahmad Ebadi ^2*

^1.Assistant Professor of Cardiac Anesthesiology MD, Department of anesthesiology, Shahid Sadoughi University of Medical Sciences-Yazd, Iran

^2.Associate Professor of Cardiac Anesthesiology MD, Department of Cardiac Anesthesiology, Golestan Hospital, and Pain Research Center, Ahvaz Jundishapur Universityof Medical Sciences, Ahvaz, Iran

*Corresponding Author E-mail: Ebadi1959@ajums.ac.ir

Contact Authors:

Ahvaz Jundishapur Universityof Medical Sciences, Golestan Hospital Cardiovascular Anesthesia, Ahwaz, Khuzestan, IRAN, Dr Ahmad Ebadi Telephone: +989161110099 Work Fax: +986113743017

Abstract: Background: Many researches show risk factors of cardiac disease in individuals suffering from chronic kidney disease(CKD).In CKD patients who are candid CABG, there are great concerns about acute kidney injury. Increase in serum Creatinine is associated with increase in morbidity and mortality in CAGB patients. Therefore, purpose of this study is investigating serum creatinine variation and GFR after oral NAC injection in CKD patients who are candid for CABG. Material and Method: 50 patients candid for CAGB were selected in blind design randomized, clinical trial in Golstan and Imam' hospitals in Ahvaz during 2010-2011. All patients had nephropathy type 2 based on kidney fund classification and had diagnostic criteria for chronic kidney diseases or it lasts for three months (GFR<90, Cr>1.5).Intervention group received 600mg oral NAC twice a day from one day before surgery to 5 days after surgery through esophagus catheter and control group received distilled water with same amount and volume. Finaly the serum creatinine, GFR and some other factors were measured. Results: There is a significant difference inserum creatinine(P=0.002), GFR(P=0.002) and BUN (P=0.034) between control and intervention groups after 5days. Conclusion: Results of this study and its comparison with other studies showed great disagreement about effect of NAC on serum creatinine but considering lack of side effects or severe changes in serum creatinine in NAC receiving patients, it can be used as a safe drug.

[Mehdi Dehghani Firoozabadi, Ahmad Ebadi. The effect of oral N-acetylcysteine on serum creatinine in chronic kidney diseases patients under CABG surgery. Life Sci J 2014;11(5s):1-6]. (ISSN:1097-8135). http://www.lifesciencesite.com. 1

doi:10.7537/marslsj1105s14.01

Key words:N-acetylcysteine, serum creatinine, GFR, chronic kidney diseases(CKD), CABG

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Proper Teleparallel Homothetic vectors From Non Diagonal Tetrad Of Some Well Known Static Spacetime

Suhail Khan ^*1, Tahir Hussain ², Gulzar Ali Khan ², Amjad Ali³

¹ Department of Mathematics, Abdul Wali Khan University Mardan KPK, Pakistan

² Department of Mathematics, University of Peshawar, Peshawar KPK, Pakistan

³Department of Basic Sciences and Islamiyat, University of Engineering and Technology, Peshawar KPK, Pakistan

^*suhail_74pk@yahoo.com

Abstract: In this paper proper teleparallel homothetic vectors for static cylindrically symmetric spacetime in context of teleparallel theory of gravitation has been investigated. For the purpose non diagonal tetrad of static cylindrically symmetric spacetime has been chosen and direct integration technique is applied to solve the teleparallel homothetic equations. It comes out that the above spacetime with non diagonal tetrad admit proper teleparallel homothetic vector for the special choice of metric functions.

[Khan S, Hussain T, Khan G. A, Ali. A. Proper Teleparallel Homothetic vectors From Non Diagonal Tetrad Of Some Well Known Static Spacetime. Life Sci J 2014;11(5s):7-10]. (ISSN:1097-8135). http://www.lifesciencesite.com. 2

doi:10.7537/marslsj1105s14.02

Keywords: Teleparallel theory, Tetrad fields, Weitzenböck connections, Proper teleparallel homothetic vectors.

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Teaching analysis of synharmonic sound in the Kazakh language

A. Zhunisbekov ¹, M. Taldybaeva ², B.A. Ospanova ^{2, G. O. Berkinbaeva 3}

¹A.Baitursynov Institute of Linguistics, Almaty, Republic of Kazakhstan (050010 Kurmangazy, 29)

²K.A.Yasawi International Kazakh-Turkish University, Turkistan, Kazakhstan (161200, B. Sattarkhanov 29)

³Abai Kazakh National Pedagogical University, Almaty, Republic of Kazakhstan

saltanur@mail.ru

Abstract: One of the urgent problems of modern linguistics is still a need for educational and methodical analysis of synharmonic sounds in Turkic (including Kazakh) languages. Theoretical and practical (especially teaching) research of specificity of phonological and phonetic organization of Turkic word is an important component of the general linguistic problems. Lack or insufficient research on synharmonic verbal prosody led to a "Eurocentric" and interpretation of segmental super segment of phenomena in phonetics of the Turkic languages. The results will be theoretical and illustrative supplement in section of phonetics textbooks and teaching aids on the Kazakh language.

[A. Zhunisbekov, M. Taldybaeva, B.A. Ospanova, G. O. Berkinbaeva. Teaching analysis of synharmonic sound in the Kazakh language. Life Sci J 2014;11(5s):11-17]. (ISSN:1097-8135). http://www.lifesciencesite.com. 3

doi:10.7537/marslsj1105s14.03

Keywords: synharmonism, singem, allosingem, prosody of speech, articulation, perception, vowels, consonants, modeling, synharmonic phonetics.

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4

Role of Gender Differences in Servicing Customers of Commercial Banks

Natalia Nikolaevna Kunitsyna

North Caucasian Federal University, Pushkina Street, 1, Stavropol, 355000, Russia

natkun2004@mail.ru

Abstract: In modern conditions commercial banks expand the list of services to clients with various methods. One of new, unoccupied segments of the banking market, having the name of "blue oceans", is the customer service proceeding from their gender differences. The priority should be given to women as they are more loyal in a choice of banking products, accept considerable part of finance solutions, pay a large number of accounts, manage family budgets. In article the directions of perspective banking servicing of women are characterized, world and Russian experience is considered.

[Kunitsyna N. Role of Gender Differences in Servicing Customers of Commercial Banks. Life Sci J 2014;11(5s):18-23]. (ISSN:1097-8135). http://www.lifesciencesite.com. 4

doi:10.7537/marslsj1105s14.04

Keywords: Bank servicing, gender distinctions, clients of bank, "blue oceans", banking products and services

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Guaranty in International Contracts

Jamshid Javani

Correspondent Author, International Law Senior Expert

Abstract: Considering complexity of trade relations especially in international level, traders are facing a huge amount of risks hampering good performance of trade relations and in some cases making them impossible. Therefore to make sure of performance and diminish the effect of such risks both sides and compensate probable damages resulting from breach of undertakings, parties to contracts implement letters of guaranty. Letters of guaranty are issued by banks, financial institutes and insurance companies. In lexical and idiomatic terms letter of guaranty is undertaking loan of someone else or in other words undertaking to bear compensation in case the undertaken is violated. Parties to a letter of guaranty are: 1) debtor 2) guarantee (beneficiary) 3) guarantor. Letters of guaranty are the best tool to secure international contracts. In international trade, letters of guaranty are used for good performance or payment and since traders are not able to freely exercise their contractual rights and compensate damages resulting from any breach, letters of guaranty become an integral part of trade and international relations. In international trades, parties to the contracts are in a strong need to banks and financial institutes to protect them against risks threatening their contracts. Therefore, banks and financial institutes issue bank letters of guaranty to guaranty performance of parties to contracts. Letters of guaranty come out in different types: 1) Ordinary letters of guaranty 2) Bank letters of guaranty 3) Guaranty L/Cs 4) insurance premiums. Each of them is applicable under the relevant terms and conditions and governing law. Governing law is one of the main issues regarding letters of guaranty. It is widely accepted that the best type of law is the one that parties to a contract may agree on and finally this fact should be taken into consideration that such letters of guaranty encourage parties to go on trading and it flourishes economy and develops trade affairs.

[Javani J. Guaranty in International Contracts. Life Sci J 2014;11(5s):24-30]. (ISSN:1097-8135). http://www.lifesciencesite.com. 5

doi:10.7537/marslsj1105s14.05

Keywords: Bank letter of guaranty, ordinary letter of guaranty, guaranty, international contracts, law governing bank letters of guaranty

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Differentiation of Mycoplasma synoviae strains in IRAN by PCR

Jamshidi Parvin, Ayazi Masoud, Nazemshirazi Mohammad Hossein

Department of Molecular Biology, Central Veterinary Laboratory of I.V.O, Tehran, Tehran- Iran

jamshidi35@gmail.com

Department of Molecular Biology, Central Veterinary Laboratory of I.V.O, Tehran, Tehran- Iran

dr.ayazi@gmail.com

Department of Molecular Biology, Central Veterinary Laboratory of I.V.O, Tehran, Tehran- Iran

nazemshiraz@yahoo.com

Abstract: Mycoplasma synoviae is one of the most important economic challenges in keeping the chickens all over the world and particularly in Iran which leads to chronic respiratory disease in chickens and turkeys. Difference in mycoplasma synoviae methods particularly in the countries that Livestock and Poultry are vaccinated with a live vaccine is a matter of great magnitude. In this paper, 1600 serum samples of 80 broiler breeder flocks were sampled on which RSA test was carried out in the Serology Laboratory. Then sampling for PCR and DNA extraction was performed through proposed methods. The results of RSA test revealed that from among 1600 serum sample taken from 80 farms, 68 farms became positive in RSA test. In General, from 1600 obtained samples, 1327 samples were positive in RSA test, 216 samples were negative, and from 57 suspected serum samples, 31 samples were reported as positive in the one-eighth dilution. Comparison of bands, obtained from the primers VlhA-F and VlhAR2, indicates that there is a difference between different strains of Iran and the vaccine strains MS-H and standard strain in terms of size. In PCR test with external primers, MSCons -F and MSCons-R, the band 350-400 indicates presence of Mycoplasma synoviae and MS-H. In general, using the DNA-diagnosis-based methods like PCR and PCR_RLFP in order to detect the Mycoplasma synoviae directly from the laboratory tissue or strains seems necessary. These methods are able to provide the detailed results in the presence of infections mixed with several Mycoplasmas, facing with secondary bacterial infections, Mycoplasma growth inhibitor such as antibiotics, or other host factors within one to two days

[Jamshidi Parvin, Ayazi Masoud, Nazemshirazi Mohammad Hossein. Differentiation of Mycoplasma synoviae strains in IRAN by PCR. Life Sci J 2014;11(5s):31-35]. (ISSN:1097-8135). http://www.lifesciencesite.com. 6

doi:10.7537/marslsj1105s14.06

Keywords: Mycoplasma synoviae strains , IRAN , PCR , high-resolution melting curve analysis

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Self Satisfaction of the Entrepreneurs in relation to the CSR Practices across Peshawar KPK Pakistan

Dr. Shahid Jan¹, Kashif Amin ² , Dr. Muhammad Tariq¹ , Dr. Zahoor Ul Haq ³ , Dr. Nazim Ali⁴

¹ Assistant Professor, Department of Management Sciences, Abdul Wali Khan University Mardan

² PhD Scholar Qurtaba University of Science and Information Technology, Peshawar

³ Professor, Department of Management Sciences, Abdul Wali Khan University Mardan

⁴ Assistant Professor, Department of Management studies, University of Malakand

shahidjan@awkum.edu.pk, kasheeamin@yahoo.com

Abstract: As the time goes on people are becoming more and more materialistic and everyone is busy in making more and more money, but the thing which is missing is the self satisfaction which makes a person relieved from materialistic thinking, tension and egoism, this study is helpful in finding out the level of self satisfaction by carrying out different CSR activities, and the findings can be generalized for the rest of the entrepreneurs. This paper is about the self satisfaction of the entrepreneurs across Peshawar KP Pakistan in relation to the CSR practices. The paper has highlighted the impact of three CSR activities namely environmental concerns, health concerns, and the literacy concerns, for this purpose a questionnaire was developed and the findings were based on the feedback of these questionnaires. The paper concludes that the said CSR activities are significantly related to the self satisfaction of the entrepreneurs across Peshawar KP Pakistan.

[Shahid Jan, Kashif Amin, Muhammad Tariq, Zahoor Ul Haq, Nazim Ali. Self Satisfaction of the Entrepreneurs in relation to the CSR Practices across Peshawar KPK Pakistan. Life Sci J 2014;11(5s):36-40]. (ISSN:1097-8135). http://www.lifesciencesite.com. 7

doi:10.7537/marslsj1105s14.07

Keywords: CSR, environmental concerns, health concerns, literacy concerns, Entrepreneurs and self satisfaction

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Evolution of a Helix Curve by observing its velocity

Nassar H. Abdel-All, M. A. Abdel-Razek , H. S. Abdel-Aziz , A. A. Khalil

Department of Mathematics, Faculty of Science, Assiut University, Assiut, Egypt.

Department of Mathematics, Faculty of Science, Sohag University, Sohag, Egypt.

E-mail: amalaboelwafa@yahoo.com (A. A. Khalil)

Abstract: In this paper, the equations of motion for a general helix curve  are derived by applying the first compatibility conditions for dependent variables ( time and arc length). As application of the equations of motions, mkdv equation is solved using symmetry method.

[Nassar H. Abdel-All, M. A. Abdel-Razek, H. S. Abdel-Aziz, A. A. Khalil. Evolution of a Helix Curve by observing its velocity. Life Sci J 2014;11(5s):41-47]. (ISSN:1097-8135). http://www.lifesciencesite.com. 8

doi:10.7537/marslsj1105s14.08

Keywords: Motion of curves, General helix curve, Symmetry of PDE, Lie’s algorithm.

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Transformational and Transactional Leadership as Predictors of Job Satisfaction, Commitment, Perceived Performance and Turnover Intention (Empirical Evidence from Malakand Division, Pakistan)

Nazim Ali¹, Shahid Jan², Arshad Ali¹, Muhammad Tariq²

¹Assistant Professor, Department of Management Studies, University of Malakand, Pakistan

²Assistant Professor, Department of Management Sciences, Abdul Wali Khan University, Pakistan

Abstract: The main aim of this research was to know the impact of transformational and transactional leadership on job satisfaction, organizational commitment, organizational citizenship behavior, employees’ perceived performance and turnover intention of public sector universities’ teachers of Malakand division of Pakistan. Data were collected from two hundred and twenty four teachers including lecturers, assistant professors, associate professors and professors. The results of correlation indicated that both transformation and transactional leadership had a significant relationship with job satisfaction, organizational commitment, perceived performance and turnover intention. The results of regression revealed that transformational leadership was a stronger predictor of job satisfaction and organizational citizenship behavior than transactional leadership while transactional leadership was a stronger predictor of organizational commitment, perceived performance and turnover intention than transformational leadership.

[Nazim Ali, Shahid Jan, Arshad Ali, Muhammad Tariq. Transformational and Transactional Leadership as Predictors of Job Satisfaction, Commitment, Perceived Performance and Turnover Intention. Life Sci J 2014;11(5s):48-53]. (ISSN:1097-8135). http://www.lifesciencesite.com. 9

doi:10.7537/marslsj1105s14.09

Key words: Transformational; transactional; leadership; job satisfaction; performance; turnover intention; Pakistan

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Standardization of Calamus CO₂-extract and study of individual fractions of herbal preparations

G.S. Ubadullaeva¹, A.K. Bochkhaeva¹, G.O. Ustenova¹, U.M. Datkhayev¹, Z.B. Sakipova¹, S.A. Tikhonova²,

 V.A. Grudko², N.Y. Bevz²

¹Kazakh National Medical University named after S.D. Asfendiyarov, Kazakhstan, Almaty

²National University of Pharmacy, Ukraine, Kharkov

kairat_phd@mail.ru

Abstract: This paper is devoted to the study of dense extract of calamus rhizomes (Acorus calamus L.), obtained in low-temperature subcritical extraction regimen by liquefied carbon dioxide from air - dry raw material at a pressure of 70 atm and a temperature range up to 30.5°C. There was determined chemical composition of the CO₂-Calamus extract, obtained in subcritical conditions. As part of the extract by gas chromatography - mass spectrometry there were revealed 40 individual substances, including various structures terpenes, ethers, aliphatic aldehydes, carboxylic acids and sterols. The most characteristic groups are camphor, linalool, otsimen and pinene. Therapeutic anti-inflammatory, analgesic and antiseptic effect of CO₂-extract of Calamus was experimentally confirmed, that due to the large content of essential oils that are represented as the main active components of terpenes.

[Ubadullaeva G.S., Bochkhaeva A.K., Ustenova G.O., Datkhayev U.M., Sakipova Z.B., Tikhonova S.A., Grudko V.A., Bevz N.Y. Standardization of Calamus CO₂-extract and study of individual fractions of herbal preparations. Life Sci J 2014;11(5s):54-59]. (ISSN:1097-8135). http://www.lifesciencesite.com. 10

doi:10.7537/marslsj1105s14.10

Keywords: standardization, Acorus calamus, CO₂-extract, spectrophotometrical analysis, chemical compose.

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Patriotic upbringing of future teachers in the course of studying of the discipline "Children's literature"

K. S. Ergobek, A. B. Mukhamedzhanova, D. K. Sartbaeva, A.S. Karpykbaeva, A.K. Bimaganbetova

Ahmed Yasawi International Kazakh-Turkish University, 29 B. Sattarkhanov Avenue, 161200 Turkistan, Kazakhstan.

Bimaganbetova-alina@mail.ru, Science@iktu.kz

Abstract: The article reveals the meaning of the concepts "patriotism" and "patriotic upbringing". The attention is focused to that remoteness of pupils from roots of the people, national traditions, moral principles results in a separation from sources, destruction of connection and continuity of generations, decline of moral, spirituality. It is revealed the role of children's literature in patriotism and civic consciousness upbringing at youth. The authors describe possibilities of the educational process of the higher school on preparing a future teacher for patriotic upbringing in the course of studying the discipline "Children's literature". On the basis of the analysis of formation of the personality’s patriotic qualities it is defined the pedagogical conditions of efficiency of patriotic upbringing in the course of studying of children's literature.

[K. S. Ergobek, A. B. Mukhamedzhanova, D. K. Sartbaeva, A.S. Karpykbaeva, A.K. Bimaganbetova. Patriotic upbringing of future teachers in the course of studying of the discipline "Children's literature". Life Sci J 2014;11(5s):60-66]. (ISSN:1097-8135). http://www.lifesciencesite.com. 11

doi:10.7537/marslsj1105s14.11

Key words: patriotism, patriotic upbringing, children’s literature, future teachers, curriculum.

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Components of coulter tractive resistance for subsoil throwing about seeds planting

M.A. Aduov, S.N. Kapov, S.A. Nukusheva, M.R. Rakhimzhanov

S. Seifullin Kazakh Agro Technical University, Zhenis Avenue, 62, Astana City, Kazakhstan;

Stavropol State Agrarian University, Zootechnicheskiy Street, 12, Stavropol City, Russia

Abstract. A coulter drills in the stubble of cultivator lancet feet well dug into the hard soil, loose top layer and destroys weeds. However existing studies show that for subsurface broadcasting seeding it is necessary to use the device for the distribution of seeds in subshare space. Uniformity of seeding depth is a major agricultural requirement for planting crops. When the seeds are embedded in the ground with a large spread in depth, shoots are obtained unharmonious, plants are lagging behind in their development, uneven are ripening. From the data of Suleimenov M.K. that the most even shoots in the untreated field were obtained with seed depth of 4.1 ... 5.6 cm. Balanced development of crops requires optimum depth of sowing, which under normal conditions is a grain of 4 to 8 cm seeds should be distributed evenly over the area of nutrition. With increasing depth setting in plants stem escape is formed there has been some increase in the depth setting of the tillering node, individual plants form a second, additional tillering node at the surface. Forming all these additional underground organs, plants are strongly depleted. With the increasing depth of seeding their germination is reduced as well.

[Aduov M.A., Kapov S.N., Nukusheva S.A., Rakhimzhanov M.R. Components of coulter tractive resistance for subsoil throwing about seeds planting. Life Sci J 2014;11(5s):67-71]. (ISSN:1097-8135). http://www.lifesciencesite.com. 12

doi:10.7537/marslsj1105s14.12

Keywords: delivery tube, ploughshare, timer spreader, wedge, driving resistance, share, cheeks.

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Research of value-and-sense system of youth as a basis for psychological resilience of a person to destructive religious movements

Zhanna Kenzhebekovna Aksakalova¹, Ulmeken Satymovna Nurgaliyeva¹, Madina Kenzhebekovna Aksakalova², Assan Emiliyevich Abdrakhmanov²

¹Kazakh State Pedagogical Institute named after Abay, Dostyk ave. 13, Almaty, 050010, Kazakhstan

²Kazakh Academy of Labour and Social Relations, Nauryzbay batyr Str. 9, Almaty, 050004, Kazakhstan

Abstract. This article described findings of the research of value-and-sense system as a basis for psychological resilience of youth to new religious movements of an extremist nature. Relevance of this theme is related to the spread of various destructive religious ideas notably amongst youth. Therefore, today, prevention of corrupt influence of destructive religious ideas on youngsters and youth is as relevant as ever. Relevant conclusions were made on difference in interrelation between terminal and instrumental values as well as in the system of life meanings of youths as a basis for psychological resilience to new religious movements.

[Aksakalova Z.K., Aksakalova M.K., Nurgaliyeva U.S., Abdrakhmanov A.E. Research of value-and-sense system of youth as a basis for psychological resilience of a person to destructive religious movements. Life Sci J 2014;11(5s):72-74]. (ISSN:1097-8135). http://www.lifesciencesite.com. 13

doi:10.7537/marslsj1105s14.13

Keywords: destructive religious organizations, destructive religious movements, value-and-sense system, psychological resilience of a person, system of values, existential vacuum, youth, self-consciousness, value-and-sense sphere, personal systems of values, motivation and needs sphere, sense sphere, values, needs, rationale, personal meaning, meaning of life, terminal values, instrumental values, system of life meaning.

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Analysis of international legislative experience in regulating the issues of environmental safety in the course of space activities 

Gulbakyt Borybekovna Kabanbayeva¹, Aigan Erzhanovna Ghatkanbayeva¹, Kulyash Nursainovna Aidarhanova¹ and Gulnar Aitzhanovna Alybaeva²

¹Al-Farabi Kazakh National University, Republic of Kazakhstan

²Humanities University of Transport and Law of a name of D. A. Kunayev, Republic of Kazakhstan 

Abstract. The author investigates international legislative regulation of ecological aspects of space activity. Today, because of broadening of space activity sphere and increase in number of the states which participate in it the problem of pollution of space itself and air and earth environment becomes up-to-date. The author investigates international law norms which restrict or prohibit space activity threatening global ecological security. The author points out to the absence of clarity in some provisions of international legislative acts in regard to ecological security in space. Regulation of harmful ecological effects resulted from space activity in very general form and without clear definitions gives wide opportunities for arbitrary interpretation of the norms of international legislative regulation.

[Kabanbayeva G.B., Ghatkanbayeva A.E., Aidarhanova K.N., Alybaeva G.A. Analysis of international legislative experience in regulating the issues of environmental safety in the course of space activities. Life Sci J 2014;11(5s):75-78] (ISSN:1097-8135). http://www.lifesciencesite.com. 14 

doi:10.7537/marslsj1105s14.14

Keywords: space activity, ecological security, international legislative regulation, damage caused.

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Device for clamping hydraulic-cylinder rod from spontaneous sinking

Nikolay Anatolyevich Baganov and Tatyana Grigoryevna Bekhtold

Kostanay Engineering Economic University named after Myrzhakyp Dulatov, Chernyshevsky Street. 59, Kostanay, 110004, Republic of Kazakhstan

Abstract. The article discusses a device by means of which there is a fixation of a hydraulic cylinder rod after hanging wheeled vehicle's axis to perform maintenance or getting out the axis from the track in rainy weather. This device prevents spontaneous lowering of the hydraulic cylinder rod while hanging the machine axis, and also can be used in hoisting mechanism of car bodies and dump trailers, excluding injury of the wheeled vehicle operator at a sudden lowering of the hydraulic cylinder rod. The use of the device - clamp allowed to increase efficiency of wheeled vehicles use for 7-9% and for 100% avoid spontaneous lowering of hydraulic cylinder rod.

[Baganov N.A., Bekhtold T. G. Device for clamping hydraulic-cylinder rod from spontaneous sinking. Life Sci J 2014;11(5s):79-81]. (ISSN:1097-8135). http://www.lifesciencesite.com. 15

doi:10.7537/marslsj1105s14.15

Keywords: wheeled vehicle, hydraulic cylinder, hydraulic-cylinder rod, clamp, injury risk, machine centerlines, maintenance and repair of the machine.

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Ethno cultural traditions of a national suit in design of modern clothes

Rakhiya Abrashetovna Darmenova, Guldarhan Kalievna Rysbaeva, Ulzhan Nygmanovna Alashabaeva

Kazakh State Women Pedagogical University, Mukhametzhanova str. 65, Almaty, 050052, Republic of Kazakhstan

Abstract. Relevance of research, is not only connected with the study of the features of using the traditional costume as one of the sources in the design and creative fashion designers of Kazakhstan, but also with the need to disclose his aesthetic and artistic features in organic synthesis of historical and cultural and artistic approaches to the test material. One of the trends of modern fashion is etnostil - well-established practice in the creative fashion designers that enable modern man to stay in touch with their national origins.

[Darmenova R.A., Rysbaeva G.K., Alashabaeva U.N. Ethno cultural traditions of a national suit in design of modern clothes. Life Sci J 2014;11(5s):82-85]. (ISSN:1097-8135). http://www.lifesciencesite.com. 16

doi:10.7537/marslsj1105s14.16

Keywords: сostume, culture, design, arts and crafts, taste, esthetics.

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Enhancing the efficiency of government control over agroindustrial sector to maintain food security

Aynash Akimsalovna Esekeeva, Araylym Kuanyshbekovna Dzhangabulova, Makhabbat Kenzhehanovna Nakisheva, Ilyas Kadyrbekovich Kuderin, Nazgul Sabyrovna Tuyakbayeva

Аl- Farabi Kazakh National University, Kazakhstan

Abstract: The purpose of this article is to describe challenges associated with enhancement of government control over agroindustrial sector in order to maintain food security. The need for government control over agricultural industry stems from the fact that the State is accountable to its citizens for establishing their standard living conditions, food and other agricultural product supplies. This article explores the concepts, objectives and enhancement techniques for government control over agroindustrial sector, challenges associated with maintaining food security and the ways to address these challenges.

[Esekeeva A.A., Dzhangabulova A.K., Nakisheva M.K., Kuderin I.K., Tuyakbayeva N.S. Enhancing the efficiency of government control over agroindustrial sector to maintain food security. Life Sci J 2014;11(5s):86-89]. (ISSN:1097-8135). http://www.lifesciencesite.com. 17

doi:10.7537/marslsj1105s14.17

Keywords: Government Control, Agroindustrial Sector, Food Security, Legal Support, Government Functions.

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Western and eastern traditions in the sphere of human rights and freedoms: analysis of sociocultural basis

Alexandra Grigoryeva, Ardak Kapyshev, Anna Svinarchuk, Ermek Elzhanova, Dana Akhmetzhanova, Aigul Bayetova, Gulnar Tasbulatova

Abay Myrzakhmetov Kokshetau University, M. Auezov Street, 189a, Kokshetau, 000002, Republic of Kazakhstan

Abstract. The article is a summary of philosophic and sociocultural traditions in the sphere of protection of human rights and freedoms in western and eastern societies in terms of their historical formation. The authors believe that the contradictions between different regions in regard to norms and legislative initiatives are determined by philosophic perception of the world and a set of cultural traditions which influence greatly both internal and external policies of modern states.

[Grigoryeva A., Kapyshev A., Svinarchuk A., Elzhanova E., Akhmetzhanova D., Bayetova A., Tasbulatova G. Western and eastern traditions in the sphere of human rights and freedoms: analysis of sociocultural basis. Life Sci J 2014;11(5s):90-94]. (ISSN:1097-8135). http://www.lifesciencesite.com. 18

doi:10.7537/marslsj1105s14.18

Keywords: human rights, socio-cultural basis, western traditions of rights, eastern interpretation of humanism.

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Tax evasion and its influence on development of the economy of the Republic of Kazakhstan

Daniyar Altayevich Kaldiyarov, Venera Rashitovna Burnasheva, Alimzhan Daniyarovich Kaldiyarov

Zhetysu State University after I. Zhansugurov, Zhansugurov St. 187A, Taldykorgan, 040000, Republic of Kazakhstan

Abstract. Implementation of state functions assigned by government is based on the objectives and effectiveness of accumulation of funds in the state budget. The various constraints (the main factor is tax evasion) may influence on the rational implementation of this process. Timeliness and completeness of tax revenues is the key to the effective functioning of the state's economy. It should be note that the struggle with the manifestation of tax evasion is one of the most pressing topics of debate and controversy in the Republic of Kazakhstan. Proposed relevant ways and solutions will contribute to reduce the incidence of tax evasion may affect the increase tax payments to the state budget, which funds will be used to finance and economic development of the Republic of Kazakhstan.

[Kaldiyarov D.A., Burnasheva V.R., Kaldiyarov A.D. Tax evasion and its influence on development of the economy of the Republic of Kazakhstan. Life Sci J 2014;11(5s):95-103]. (ISSN:1097-8135). http://www.lifesciencesite.com. 19

doi:10.7537/marslsj1105s14.19

Keywords: Taxes, tax burden, tax evasion, concealment of income, arrears, tax culture, tax optimization

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Social study of problems of language development and lingual situation in Pavlodar region of Kazakhstan

Oleg Evgenyevich Komarov and Rishat Zhurkenovich Saurbayev

Pavlodar State Pedagogical Institute, Mira Street, 60, Pavlodar, 140000, Kazakhstan

Abstract. Among the main ways, methods and approaches to analysis of society impact on language functioning the most important is language policy. It is the most important factor that forms and changes linguistic situation both in separate regions and in country as a whole. Social indicators of realization of linguistic policy in a certain region of Kazakhstan are reviewed. This region is characterized as poly-ethnic and poly-lingual subject typical for the country of former Soviet Union. The authors of the article have researched functioning of Kazakh as state and Russian as a language of international communication on the example of Pavlodar region where shares of people speaking Russian and Kazakh languages are almost equal – 50% each.

[Komarov O.E., Saurbayev R.Z. Social study of problems of language development and lingual situation in Pavlodar region of Kazakhstan. Life Sci J 2014;11(5s):104-110]. (ISSN:1097-8135). http://www.lifesciencesite.com. 20

doi:10.7537/marslsj1105s14.20

Keywords: Kazakh language, Russian language, language functioning, ethno-linguistic situation, state linguistic policy.

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Implementation of integrated QMS at the cereals enterprises in Northern Kazakhstan

Viktor Stanislavovich Kuhar

Kostanaiskiy Engineering and Economic University named after M. Dulatov, Chernyshevsky, 59, Kostanai, 110000, Republic of Kazakhstan

Abstract. Quality of products - is one of the key tools of competition, obtaining and keeping positions at the markets. Quality management is the main part of production process. The task of QM is to check-up of quality of products in the process of production rather then finding out of defected items. Skillful realization of the principles and mechanisms of standardization, metrology, certification and quality management facilitates the process of efficient reformation of economy and integration of Kazakhstan into world community. Solution of these issues moved all developed countries to practically new stage characterized by integrated systems of quality management (IQMS) based on QSM, systems of ecological management (EMS) or system of environmental management (EMS), and professional security and health management systems (PSHMS).

[Kuhar V.S. Implementation of integrated QMS at the cereals enterprises in Northern Kazakhstan. Life Sci J 2014;11(5s):111-115]. (ISSN:1097-8135). http://www.lifesciencesite.com. 21

doi:10.7537/marslsj1105s14.21

Keywords: quality of products, quality management, ecological management, environmental management, professional security, health management systems

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Specifics of pigs’ growth depending on growing conditions considering physiological maturity

Ai-Gul Seralievna Segizbaeva

Kostanau Engineering-Economical University named after M. Dulatov, Chernishewska strit 59, Kostanau, Respublica Kazakstan

Abstract. Sow polycarpicae is important for meet production increase. But using technological solutions for breeding, environmental impact and sow polycarpicae decrease the quality of born pigs. Pigs with different physiological maturity are born that affects their quality. According to several researches from 16 to 45% of pigs in sow farrow are born in the state of physiological immaturity, physiological physiological measures do not correspond to calendar age. Results of research of growth and development of physiological immature pigs are described in the article and comparative characteristic of growth and fertility of sows born in different state of physiological maturity depending on growing conditions is provided.

[Segizbaeva A.S. Specifics of pigs’ growth depending on growing conditions considering physiological maturity. Life Sci J 2014;11(5s):116-119]. (ISSN:1097-8135). http://www.lifesciencesite.com. 22

doi:10.7537/marslsj1105s14.22

Keywords: antenatal immaturity, polycarpicae, physiological maturity, growing capacity, average daily growth

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Theoretical basics of interethnic communication research

Gulnara Seilbekovna Suyunova, Olga Konstantinovna Andryuchshenko, Lyudmila Erbulatovna Tokatova

Pavlodar State Pedagogical Institute, Mira Street, 60, Pavlodar, 140000, Kazakhstan

Abstract. The article deals with an important question in the theory of intercultural communication; it is about the possible theoretical basis of interethnic communication studies. Interethnic communication gives modern linguistics an interesting scientific and applied material, the analysis of which reveals different aspects, problems and features of such communication. Studying interethnic communication requires an access to particular scientific positions, which allow us to identify and form a theoretical basis for such studies. In this regard, the authors of this article attempted to study some regulations of classical language - philosophy, Eurasian ideology, ethnicity theory, which could form the basis of the interethnic communication theory.

[Suyunova G.S., Andryuchshenko O.K., Tokatova L. E. Theoretical basics of interethnic communication research. Life Sci J 2014;11(5s):120-124]. (ISSN:1097-8135). http://www.lifesciencesite.com. 23

doi:10.7537/marslsj1105s14.23

Keywords: interethnic communication, methodology, language-philosophy, Eurasian ideology, ethnicity, tolerance.

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Military armor of Kazakhs: ethno-linguistic description

Nartai Kuandykovich Zhusupov¹, Zhaksybai Tursinovich Sarbalayev¹, Nazira Ahanovna Shakhmetova¹, Zakiya Halyafetdinovna Latypova¹, Mahabbat Nurzhauovna Baratova¹, Asia Hasanovna Bekbosynova²

¹Pavlodar State University named after S. Toraigyrov, Lomov Street 64, Pavlodar, 140000, Republic of Kazakhstan

²Kostanai social and technical University named after Z. Aldamzhar, Herzen street 27, Kostanai, 110000, Republic of Kazakhstan

Abstract: Language embodies the uniqueness of the people, the national vision of the world and national culture [1, 2, 3, 4]. Uniqueness, originality of the language is determined by culture, mentality, “the spirit of the people”. In the study of the relationship between language, culture and ethnic consciousness the most important are the units of the language, expressing, in addition to linguistic content, and cultural knowledge. In this article – there are the names of military armor of Kazakhs. This paper is devoted to the comprehensive study of the system of traditional Kazakh weapons. Integrated approach allows us to describe military equipment in the interdisciplinary plane: at the intersection of such disciplines as history, military science, ethno-linguistics and art criticism. The article contains the terms of armaments, their traditional names in the Kazakh language and values, are described the kinds and types of weapons, their structural parts, manufacturing technology, how to use them. In addition, the system of Kazakh weapons is given in the mythological representation: structural parts of the weapon represent a model of the world. Also there described the customs and traditions associated with weapons of Kazakhs. Thus, the names of the traditional Kazakh weapons are means of national-specific development of the world. Rich information about the armed batyrs is found in the heroic epics. Therefore they stand as the material for analysis.

[Zhusupov N.K., Sarbalayev Z.T., Shakhmetova N.A., Bekbosynova A. H., Latypova Z.H., Baratova M.N. Military armor of Kazakhs: ethno-linguistic description. Life Sci J 2014;11(5s):125-131]. (ISSN:1097-8135). http://www.lifesciencesite.com. 24

doi:10.7537/marslsj1105s14.24

Keywords: language, culture, ethnicity, ethnic consciousness, ethnic identity, model of the world, ethno-linguistic aspect, the Kazakh weapons.

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Turkic poetry and Mashkhur Zhusip

Nartay Zhuzupov, Muhhabat Baratova, Ayman Zeynullina, Zhaksybay Tursynovich Sarybalayev, Bakytzhan Masalimovna Kadyrova

Pavlodar State University named after S. Toraygyrov, Lomova 64, Pavlodar, 140008, Kazakhstan

Abstract. In the epoch of priority and authoritarianism, the literary heritage of previous ages was analyzed only from the perspective of class character, consequently, a lot of edges turned out to be unrevealed from the perspective of authentically scientific approach. There are good reasons to assert that the obtainment of sovereignty by Kazakhstan in the beginning of 1990 of the previous century provided an opportunity to study "blank spaces" in art, including fiction. Nevertheless, incompleteness of creation of centralized fund of ancient script samples, the lack of adequate control over the storage of ancient writings and other reasons created serious obstacles for the study of literary heritage, making the problem still urgent. The article deals with the analysis of material, devoted to creative work of the famous Kazakh poet Mashkhur Zhusip Kopeev, uninvestigated in world cultural heritage and literary studies. The problems of style peculiarities of poems of Mashkhur Zhusip and his connections with the Turkic poetry of Middle Asia are studied on the basis of definite facts. Genres, linguistic and stylistic peculiarities of works of Turkic poets of Middle Asia are fundamentally studied in comparison with the works of Mashkhur Zhusip. Based on the analysis of works of Turkic poets and Mashkhur Zhusip, genre and stylistic peculiarities of works of kindred Turkic nations, which were not studied in the epoch of rule of the Communist Party of the Soviet Union, are subject to critical re-evaluation for the first time in complex and integration.

[Zhuzupov N., Baratova M., Zeynullina A., Sarybalayev Z.T., Kadyrova B.M. Turkic poetry and mashkhur zhusip. Life Sci J 2014;11(5s):132-139]. (ISSN:1097-8135). http://www.lifesciencesite.com. 25

doi:10.7537/marslsj1105s14.25

Keywords: the works of Turkic nations, genre uniqueness, Kazakh cultural heritage, stylistic peculiarities of literary studies.

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Making up of the logarithmic equations by complication method

Akan Alpysov and Zhazira Mukanova

Pavlodar State Pedagogical Institute, Mira Street, 60-303, Pavlodar, 140006, Kazakhstan

Abstract: In materials of article methods of making up of tasks are considered by complication. This method promotes formation of mathematical thinking and development of powers of thinking being trained. By independent drawing up of tasks logic regularities are used, new communications between the mathematical facts that promotes a creative approach during the studying mathematics reveal. According to a complication method by making up of the logarithmic equations properties of logarithmic function and laws of mathematical transformations are staticized, and it develops ability of management of own thinking activity. We understand transition as complication from simple expressions to the difficult structures containing big information loading. Complication – process return to process of reduction which introduces more in process of formation and knowledge development. In article ways of application of this method and its role in the course of gradual development of cogitative activity are considered. Our purpose also consists in it. Thus, in the publication requirements for performance of conditions of application of a method of complication in the course of making up of tasks and also a way of realization and methods of formation of cogitative activity of the being trained are considered.

[Alpysov A., Mukanova Z. Making up of the logarithmic equations by complication method. Life Sci J 2014;11(5s):140-144]. (ISSN:1097-8135). http://www.lifesciencesite.com. 26

doi:10.7537/marslsj1105s14.26

Keywords: Making up of the logarithmic equations, method of complication of the equation

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Activization of self-education of students – psychologists

Arna Zhartaevna Aplashova¹, Bibisara Aubakirovna Amirova², Saltanat Kuatovna Abildina², Meiramgul Maksutovna Tusupova², Uldar Ibrashevna Autalipova³

¹Pavlodar State Pedagogical Institute, Pavlodar, Kazakhstan

²Karaganda State University named after E. Buketov, Karaganda, Kazakhstan

³Kazakh Women's Pedagogical University, Almaty, Kazakhstan

Abstract. In article the essence of self-education of students- psychologists on the basis of the theoretical analysis of a readiness of a problem in the theory and practice is defined. Self-education of students psychologists is a process and result of development in students psychologists of abilities of statement of a self-educational educational task; realization of self-educational educational actions and operations; self-checking behind a course of the solution of a self-educational educational task and self-image of result. Pedagogical conditions of activization of self-education of students- psychologists of faculty of psychological sciences of the state teacher training college are defined. The Model of self-education of students-psychologists taking into account pedagogical conditions of its activization is developed. Pedagogical efficiency of the offered Model of self-education of students- psychologists is experimentally checked and proved. On the basis of the received experimental data conclusions are drawn and recommendations about improvement of self-education of students psychologists are offered.

[Aplashova A.Z., Amirova B.A., Abildina S.K., Tusupova M.M., Autalipova U.I. Activization of self-education of students – psychologists. Life Sci J 2014;11(5s):145-148]. (ISSN:1097-8135). http://www.lifesciencesite.com. 27

doi:10.7537/marslsj1105s14.27

Keywords: Self-education of students psychologists, pedagogical conditions of activization of self-education of students psychologists

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Linguistic worldview: of the world: linguistic and national particularities

Aizhan Saburtanovna Dalabayeva

Ablaikhan Kazakh University of International Relations and World Languages, Muratbayeva Street, 200, Almaty, 050022, Republic of Kazakhstan

Abstract. Language is integral and most important part of any national culture, material base which must be studied along with historical, geographic, economic and other determinant before familiarization with this culture but the key point is penetration into the way of thinking of the nation, an attempt to look at the world with the eyes of bearers of this culture. It is not by coincidence that the President of the Republic of Kazakhstan N. Nazarbayev believes that "National language forms national consciousness". The article showed the essence of language picture of the world (LPW), the notion of national language picture is analyzed, the relationship between national culture and language is considered and necessity to study LPW in order to understand culture of other nation is explained. Particularities of LPW of the Kazakh and Russians are considered as exemplified by equivalent-free, background and connotative lexis, and words-concepts.

[Dalabayeva A.S. Linguistic worldview: of the world: linguistic and national particularities. Life Sci J 2014;11(5s):149-152]. (ISSN:1097-8135). http://www.lifesciencesite.com. 28

doi:10.7537/marslsj1105s14.28

Keywords: LPW, national LPW, equivalent-free lexis, background lexis, connotation lexis, connotative lexis, connotative language zone, words-concepts

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Professional training of students during the studying sociological, philosophical, legal disciplines

Nurzhamal Nurzhanovna Kazieva, Bakyt Ramazankyzy Ramazan, Karlygash Temirbolatovna Kabdulina, Zhanbolat Temirbolatovich Kabdulin, Janat Zhantemirovich Sakenov

Pavlodar State Pedagogical Institute, Mira Street, 60-303, Pavlodar, 140006, Kazakhstan

Abstract. The role of sociological, philosophical, legal disciplines locates in article in professional training of students in the conditions of the changes occurring in modern education. As a theoretical and methodological basis of professional training of students during the studying sociological, philosophical, legal disciplines the competence approach is offered. Process of professional training of students during the studying the sociological, philosophical, legal disciplines which essence consists in mastering by the professional competences necessary for pedagogical activity locates. Professional readiness of students from a position of formation of knowledge on sociological, philosophical, legal disciplines, ability to use this sociological, philosophical, legal knowledge locates in professional activity for the solution of problems of the education considering specifics of specialty. The Model of professional training of students locates during studying sociological, philosophical, legal disciplines in modern conditions of preparation of students to professional activity. Efficiency of Model of vocational training of students is experimentally proved when studying sociological, philosophical, legal disciplines.

[Kazieva N.N., Ramazan B.R., Kabdulina K.T., Kabdulin Z.T., Sakenov J.Z. Professional training of students during the studying sociological, philosophical, legal disciplines. Life Sci J 2014;11(5s):153-156]. (ISSN:1097-8135). http://www.lifesciencesite.com. 29

doi:10.7537/marslsj1105s14.29

Keywords: Professional training of students, professional training of students when studying sociological, philosophical, legal disciplines

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The reasons of non-performing loans and perspectives of economic growth

Zhanna Mingaleva¹, Myrzabike Zhumabayeva² and Gulzhan Karimbayeva³

¹Perm National Research Polytechnic University, Komsomolsky Av. 29, Perm, 614000, Russia

²International Academy of Business, Rozybakiyev Av. 227, Almaty, 050060, Kazakhstan

³Kazakh Humanitarian Law University, Korgalgyn Rd. 8, Astana, 010000, Kazakhstan

Abstract. Sudden growth of NPL volume became one of the up-to-date problems of bank sector in late 2000s. Analysis of macroeconomic values of development of Eastern, Central and South Europe, CIS-countries showed that before financial crisis of 2007-2008 the situation with credit portfolios in most countries of the world were rather stable. However world financial crisis changed situation seriously in financial sector - the average quality of bank assets has deteriorated greatly and a number of general problems of development became clear. This article is devoted to analysis of main reasons of NPL growth in modern economy and the evaluation of effects of their influence on national economies. The article analyses the reasons of origination of bad assets (NPL) and considers them in terms of opportunities of national economies. Comparative characteristics of the factors and reasons for non-elimination and growth of bad assets in Russia, CIS-countries, European countries are provided.

[Mingaleva Z., Zhumabayeva M., Karimbayeva G. The reasons of non-performing loans and perspectives of economic growth. Life Sci J 2014;11(5s):157-161]. (ISSN:1097-8135). http://www.lifesciencesite.com. 30

doi:10.7537/marslsj1105s14.30

Keywords: non-performing loan, economic growth, crediting of real sector, recession, investment potential of bank sector

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Investment in road infrastructure and regional economic development

Мadina Umargalievna Rakhimberdinova

T. Ryskulov Kazakh Economic University, Zhandosov Street, 55, Almaty, 050035, Kazakhstan

Abstract. The paper deals with the impact of investment in regional road infrastructure on the regional economic development. The key trends and economic effects of investment in the regional road network are identified. Ensuring of sustainable development, improving of investment climate, increasing of competitiveness of the national economy, creating conditions for Kazakhstan's to transit to innovative development, stimulating of regional development is largely dependent on the availability and quality of infrastructure, road network being an important component here.

[Rakhimberdinova М.U. Investment in road infrastructure and regional economic development. Life Sci J 2014;11(5s):162-165]. (ISSN:1097-8135). http://www.lifesciencesite.com. 31

doi:10.7537/marslsj1105s14.31

Keywords: road infrastructure, economic effects, social effects, regional development

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Pedagogical conditions of formation professional competences at students (on an example of the Pedagogics and psychology specialty)

B.G. Sarsenbaeva, N.V. Nikolaeva, Z.K. Kulsharipova, R.N. Demidenko, V.V. Vlasova, J. Z. Sakenov

Pavlodar State Pedagogical Institute, Mira Street, 60-303, Pavlodar, 140006, Kazakhstan

Abstract. In article the analysis of a status of the problem consisting in justification of pedagogical conditions of formation of professional competence at students (on an example of the Pedagogics and psychology specialty) in the course of their vocational training is carried out. The structure is developed, the contents, criteria and levels professional competences at students (on an example of the Pedagogics and psychology specialty) are defined. Efficiency of the revealed pedagogical conditions of the vocational training providing formation of professional to competence at students (on an example of the Pedagogics and psychology specialty) is checked. The model of formation of professional competence of students of the Pedagogics and psychology specialty is developed. Efficiency of model of formation of professional competence of students of the Pedagogics and psychology specialty in the course of vocational training is experimentally checked.

[Sarsenbaeva B.G., Nikolaeva N.V., Kulsharipova Z.K., Demidenko R.N., Vlasova V.V., Sakenov J. Z. Pedagogical conditions of formation professional competences at students (on an example of the Pedagogics and psychology specialty). Life Sci J 2014;11(5s):166-170]. (ISSN:1097-8135). http://www.lifesciencesite.com. 32

doi:10.7537/marslsj1105s14.32

Keywords: Pedagogical conditions of formation professional competences, professional competence of students (on an example of the Pedagogics and psychology specialty).

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Molecular-genetic identification of emerged novel invasive pathogens of Asiatic Elm Ulmus pumila L

¹M. Turaliyeva, ¹A.Yeshibaev, ² I. Digel, ¹G. Elibayeva, ¹A. Sydykova, ¹A. Uspabayeva, ³G. Dosybayeva, ¹A. Zhylysbayeva and ³K. Lakhanova 

¹ Department of Biotechnology, South Kazakhstan State University named after M. Auezov, Shymkent, Kazakhstan

² Institute of Bioengineering, FH Aachen University of Applied Sciences, Juelich, 52428, Germany

³Kh.Yassavi International Kazakh-Turkish University, Divaeva Str. 142/9, Shymkent, 160013, Kazakhstan 

Abstract. The dwarf elm Ulmus pumila L. (Ulmaceae) is one of indigenous species of flora in Kazakhstan and forms a basis of dendroflora in virtually all settlements of the region. In the past decade, multiple outbreaks of previously unknown diseases of the small-leaved elm have been registered. In our study, by the molecular-genetic analysis it was found that the pathogens responsible for the outbreaks are microfungi belonging to the genus Fusarium – F. solani and F. oxysporum. The nucleotide sequences (ITS regions) isolated from the diseased trees showed very high similarity with the GenBank control numbers EU625403.1 and FJ478128.1 (100.0 and 99.0 % respectively). Oncoming research will focus on the search of natural microbial antagonists of the discovered phytopathogens.

[Turaliyeva M., Yeshibaev A., Digel I., Elibayeva G., Sydykova A., Uspabayeva A., Dosybayeva G., Zhylysbayeva A., Lakhanova K. Molecular-genetic identification of emerged novel invasive pathogens of Asiatic Elm Ulmus pumila L. Life Sci J 2014;11(5s):171-175]. (ISSN:1097-8135). http://www.lifesciencesite.com. 33

doi:10.7537/marslsj1105s14.33

Keywords: Phytopathogen, dwarf elm, Fusarium, toxicity, micromycetes, antagonists, molecular-genetic analysis

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Solution of the problem of transient process in the circuit, whose nonlinear element I-V characteristic is a polynomial

Assel Anuarkyzy Yerzhan, Zautbek Kuralbaevish Kuralbayev, Gulzada Dauletbekovna Musapirova

Almaty University of Power Engineering & Telecommunications, Baytusynova Str. 126, Almaty, 050013, Kazakhstan

Abstract. For the analysis and design of electronic circuits, a mathematical model of possible processes that can occur in a particular circuit under consideration, is developed. As the result of this modeling differential and algebraic equations will be obtained. However, the current-voltage characteristics of nonlinear elements that make up the circuit and determine the relationship between the current and the voltage may not be set in the form of an analytical dependence. For solution of differential equations describing the processes in the circuit, it would be useful to have such dependence. Therefore, the determination of the current-voltage characteristics of non-linear elements in the form of an analytical formula is the actual problem. This article is devoted to the determination of the current-voltage characteristic of the nonlinear element (varistor) in the circuit, and solving the problem of the transient process in it, arising under external influence.

[Yerzhan A. A., Kuralbayev Z.K., Musapirova G.D. Solution of the problem of transient process in the circuit, whose nonlinear element I-V characteristic is a polynomial. Life Sci J 2014;11(5s):176-182]. (ISSN:1097-8135). http://www.lifesciencesite.com. 34

doi:10.7537/marslsj1105s14.34

Keywords: varistor, electronic circuits, mathematical model, current-voltage characteristics, non-linear elements.

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Strategies to develop transnational companies in the world market

Gulzira Bulatovna Yestekova¹, Assel Kenesovna Jumasseitova¹, Rimma Nurmuhanbetovna Zhangirova²

¹Kazakh British Technical University, Tole bi street 59, Almaty, 050000, Kazakhstan

²Kazakh National Pedagogical University Named After Abai, Dostyk Avenue 13, Almaty 050000, Kazakhstan

Abstract. The author considers key principles of development of transnational companies. The theories of origination and the stages of development of transnational companies are defined. Modern trends in formation of strategies of transnational companies development are identified, author’s study of strategies of development of a number of transnational companies allowed to find main tools of organization of this process. The conclusion is made that further development of transnational companies is determined by 2 key approaches to regionalization at which new conditions for organization of investment projects appear. These conditions change not only business environment to make transaction but the mechanisms of interaction of the entities of regional economic relations, and deepening of integration processes suggests stimulation of economic growth, growth of competitiveness of goods and services and more efficient use of single markets' potential.

[Yestekova G.B., Jumasseitova A.K., Zhangirova R.N. Strategies to develop transnational companies in the world market. Life Sci J 2014;11(5s):183-187]. (ISSN:1097-8135). http://www.lifesciencesite.com. 35

doi:10.7537/marslsj1105s14.35

Keywords: Strategy, transnational companies, state, development, integration, innovation, regionalization

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Features of application of norms of a common law in Turkestani edge at the end of the XIX century – the beginning of the XX century

Ualikhan Akypbekovich Akhatov¹, Askat Ilyasovich Darkenbayev¹, Ermek Talantuly Nurmaganbet²

¹Al-Farabi Kazakh National University of on Educational, Methodical and Educational Work, Kazakhstan

²Al-Farabi Kazakh National University of on Scientific and Innovative Activity and International Relations, Kazakhstan

Abstract: This richly detailed study traces the shared history of Russia and Turkestan in the period of the end of the XIX century – the beginning of the XX century. An aggressive and colonizer policy from the Russian Empire in the XIX century led to the creation of Turkestani edge. The author considers the special model of court system on Turkestani territory under the Russian Empire power. This system was created by judicial authority of the imperial Russia as a combination of two systems - biev court and kaziev court. These courts were based on Sharia and a traditional common law of steppe democracy.

[Akhatov U.A., Darkenbayev A.I., Nurmaganbet E.T. Features of application of norms of a common law in Turkestani edge at the end of the XIX century – the beginning of the XX century. Life Sci J 2014;11(5s):188-191]. (ISSN:1097-8135). http://www.lifesciencesite.com. 36

doi:10.7537/marslsj1105s14.36

Keywords: Turkestani, Imperial Russia, biev court, kaziev court, traditional common law, steppe democracy

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Legal regulation of agriculture in Kazakhstan: problems and prospects

Gulnar Tuleukhadirovna Aygarinova¹, Dana Sabyrkhanovna Smagulova¹, Zhanna Baybekovna Akshatayeva², Maksat Abdumutalipuly Elikbay², Gulshat Rakhmetovna Rakhmetova²

¹Аl-Farabi Kazakh National University, Kazakhstan

²Auezov South Kazakhstan State University, Kazakhstan

Abstract: The problem of food security is the top priority of the economic policy strategy of any state, the effectiveness of this solution influences social, political, and ethnic stability in society. Food security, as an integral part of national security depends considerably on public resources aimed at preventing imbalance in the market, production and social environment of the country. Formation of public resources for all types of food, public grains resources and other strategically important agricultural products in the right quantities, depending on the needs of the population, is able to provide food security. The global financial crisis that affected the agricultural sector and the economy, created a real threat to global food security, and this in turn requires a reform of existing mechanisms and development of new ones to ensure food security at the international and national levels. Economic, political, and social security in the modern world is based on three aspects of security - food, energy and finance. According to the UN, more than 925 million people around the world suffer from hunger. This represents 12.5 percent of the world population (every eighth person). Of these, the vast majority - 852 million people - live in developing countries, where 14.9 percent of the population is starving. The number of hungry people in the world remains unacceptably high. Given the current rate of the population growth, global food production must increase by 70% by 2050, while the population of the world to this time should reach 9 billion people.

[Aygarinova G.T., Smagulova D.S., Akshatayeva Z.B., Elikbay M.A., Rakhmetova G.R. Legal regulation of agriculture in Kazakhstan: problems and prospects. Life Sci J 2014;11(5s):192-198]. (ISSN:1097-8135). http://www.lifesciencesite.com. 37

doi:10.7537/marslsj1105s14.37

Keywords: food security, agrarian entrepreneurship, Kazakhstan, agrarian legislation

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Legal forms of veterinary safety provision 

Lyazzat Kalymbekovna Erkinbayeva¹, Bakhytzhan Kalymbek², Gulnar Tuleukhadirovna Aygarinova², Gulmira Kuralbekovna Shulanbekova² 

¹I. Zhansugurov Zhetysu State University, Kazakhstan

²Аl-Farabi Kazakh National University, Kazakhstan 

Abstract. In the article, there is defined the conception and content of veterinary safety and also are stated the problems of veterinary safety enforceability of the country under the conditions of integration process and world economy globalization. On the ground of theoretical provisions’ analysis of contemporary experience of Kazakhstan, applicable Kazakh legislation, there were developed recommendations and proposals for veterinary safety improvement of the Republic of Kazakhstan.

[Erkinbayeva L.K., Kalymbek B., Aygarinova G.T., Shulanbekova G.K. Legal forms of veterinary safety provision. Life Sci J 2014;11(5s):199-202]. (ISSN:1097-8135). http://www.lifesciencesite.com. 38

doi:10.7537/marslsj1105s14.38

Keywords: veterinary safety, veterinary control, veterinary-sanitary examination.

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Development of the concept of effective growth of sugar production in Kazakhstan

Daniyar Altayevich Kaldiyarov, Askar Kaliyevich Sharipov, Asel Ericovna Bedelbayeva

Zhetysu State University named after I. Zhansugurov, Zhansugurov Street, 187А, Taldykorgan, 040000, Republic of Kazakhstan

Abstract. The article consides theoretical and practical problems of development of beet sugar production and increase of efficiency of its functioning in the conditions of the uniform Customs union, and also the entry of Kazakhstan into the World Trade Organization. Also article describes the main problems and development of the concept of integrated solutions to many economic, organizational and legal aspects of the effective sugar industry development. Developed concept ensures effective functioning of sugar beet production in the agricultural sector.

[Kaldiyarov D.A., Sharipov A.K., Bedelbayeva A.E. Development of the concept of effective growth of sugar production in Kazakhstan. Life Sci J 2014;11(5s):203-209]. (ISSN:1097-8135). http://www.lifesciencesite.com. 39

doi:10.7537/marslsj1105s14.39

Keywords: beet-sugar industry, efficient development, agriculture, agribusiness, government regulation.

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The synthesis and antimicrobial activity of new piperidine compounds

Manas Toktasynovich Omyrzakov¹, Dauletkeldy Kerimovich Kiyashev¹, Nurjan Bahtashevich Kurmankulov², Ksenija Aleksandrovna Bortnikova², Kazbek Bekmaganbetovich Erzhanov², Madi Toktasynuly Omirzak²

¹Kazakh National Medical University named SD Asfendiyarov, Tole str. 88, Almaty, 050012, Kazakhstan

²Institute of Chemical Sciences of A.B. Bekturov, Sh.Ualikhanov str. 106, Almaty, 050010, Kazakhstan

Abstract. Year after year, we are seeing the increasing amount of scientific and patent data on the use of various piperidine-containing compounds as medicinal drugs. This indicates that such a group of synthons has good prospects for searching new biologically active compounds based on them [1, 2 and 3]. This paper contains the findings of synthesizing new piperidinous heterocyclic compounds for creating medicinal drugs due to their high biological activity. The structure and characteristics of synthesized compounds were analyzed using IR and NMR (¹H and ¹³C) spectroscopy. Nonpathogenic microbial strain tests detected new active substances with good prospects. These compounds can take part in additional tests on detecting antimicrobial activity in a wider range of microorganisms.

[Omyrzakov M.T., Kiyashev D. K., Kurmankulov N.B., Bortnikova K.A., Erzhanov K.B., Omirzak M.T. The synthesis and antimicrobial activity of new piperidine compounds. Life Sci J 2014;11(5s):210-214]. (ISSN:1097-8135). http://www.lifesciencesite.com. 40

doi:10.7537/marslsj1105s14.40

Keywords: piperidine heterocycles, piperidone, Favorskii reaction, Mannich aminomethylation reaction, antimicrobial activity.

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Linguistic mechanisms of pre-substantive clauses in communicative aspect

Aigul Yskakkyzy Safargalieva

Kazakh National Technical University after K.I. Satpayev, Satpayev Str. 22, Almaty, 050013, Kazakhstan

Abstract. This article is devoted to analysis of linguistic mechanisms of pre-substantive clauses in Russian language in communicative aspect. The article actualizes the idea that any complex sentence being a unit of higher syntax level is intended mainly for realization of main function of the language – communicative function and therefore study of language units in terms of structural-semantic character must be considered as a tool for achieving of some communicative aims.

[Safargalieva A.Y. Linguistic mechanisms of pre-substantive clauses in communicative aspect. Life Sci J 2014;11(5s):215-218]. (ISSN:1097-8135). http://www.lifesciencesite.com. 41

doi:10.7537/marslsj1105s14.41

Keywords: pre-substantive clauses, communicative grammar, communicative perspectives, linguistic mechanisms

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Difficulties in the teaching of Russian as a foreign language: the perspectives of an ethnically Tatar specialist in Russian philology and an American student

Daniya Salimova, Hope Johnson

Kazan Federal University (Elabuga), Kazanskaya Ulitsa, 89, Yelabuga, 423600, Republic of Tatarstan

Abstract: This article examines the experience of a United States citizen who studied on an individual basis under the guidance of three teachers, each of whom was responsible for a specific thematic or grammatical topic with the goal of improving speaking proficiency. Analyses of the difficulties in studying Russian are given from the point of view of both teacher and pupil. The relevance of the topic is evident, as the multilingual twenty-first century is characterized by the practical need for the development and improvement of both individual and collective methods of language teaching. This research may be used in the immediate practice of teaching Russian as a foreign language and may also broaden understanding in the sphere of multicultural communication.

[Salimova D., Johnson H. Difficulties in the teaching of Russian as a foreign language: the perspectives of an ethnically Tatar specialist in Russian philology and an American student. Life Sci J 2014;11(5s):219-223]. (ISSN:1097-8135). http://www.lifesciencesite.com. 42

doi:10.7537/marslsj1105s14.42

Keywords: Russian as a foreign language, teaching, methodology, language barrier, grammatical difficulties, multifaceted approach

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Parenting potential of a family of a Ural monotown

Elena Vladimirovna Satybaldina

Urals Federal University named after B.N. Yeltsin, Prospect Mira 19, Yekaterinburg, 620002, Russia

Abstract. The necessity to study modern families, reveal the parenting strategies of a modern Russian family is, first of all, determined by the special significance of a family as one of the fundamental mechanisms of social life reproduction. The importance of implementation of the parenting function by a family resides in developing and functioning of a sound society and in the processes of determining the future of this society. The multivariate approaches to formation of living strategies of a family in the sphere of parenting, the prevailing of studying the parenting within the framework of pedagogy have determined the selection of this article’s subject. Change of various spheres of Russian society has caused a series of significant socio-economic and spiritually moral changes, which have clearly manifested themselves in destroying the former and searching for new value references, organization structures, models of personalized, business, and family relationship. In 2010, the author carried out a sociological research targeting studying a family of a modern Ural monotown. The article analyzes the peculiar features of the family culture of plant workers and the plant's corporate culture, which influence greatly everyone who is inside of it, and which have the strong potential in preventing various forms of deviant behavior.

[Satybaldina E.V. Parenting potential of a family of a Ural monotown. Life Sci J 2014;11(5s):224-227]. (ISSN:1097-8135). http://www.lifesciencesite.com. 43

doi:10.7537/marslsj1105s14.43

Keywords: Ural monotown, family of the monotown dwellers, deviation, parenting function of a family, professional socialization.

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First results of using the digital educational resources of the e-learning system in the Kazakhstan schools

Almira Isbasarovna Tazhigulova, Yelena Viktorovna Artykbayeva, Ainur Zhalgasbaevna Arystanova

JSC “National Center of Informatization”, Zhandosov str. 61-a, Almaty, 050036, Kazakhstan

Abstract. This article describes the first results of the national project on introduction of e-learning system in the schools of the Republic of Kazakhstan. This project is being implemented in the Republic since 2011, over these years more than five and a half thousands of digital educational resources have been developed and posted in the electronic library of the e-learning system. The authors provide the automated survey data of teachers and students, who have used the digital resources in the educational process.

[Tazhigulova A.I., Artykbayeva Y.V., Arystanova A.Z. First results of using the digital educational resources of the e-learning system in the Kazakhstan schools. Life Sci J 2014;11(5s):228-230]. (ISSN:1097-8135). http://www.lifesciencesite.com. 44

doi:10.7537/marslsj1105s14.44

Keywords: e-learning, digital educational resources influence, educational process, school, personality development

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Access to environmental information in legislation of the republic of Kazakhstan

Serikkali Tynybekov, Roza Yerezhepkyzy, Aaliyah Kartbayevna Berdibayeva, Aynash Akimsalovna Esekeeva, Nurlayym Kambatyrovna Mynbatyrova, Elena Akopova

Аl-Farabi Kazakh National University

Abstract. In this article, the authors analyzed the legislation of the Republic of Kazakhstan and the ways to implement the Aarhus Convention. Questions of access to information, participations of the public in decision-making and access to justice are guaranteed by the Constitution of the Republic of Kazakhstan. Existing legislation of the Republic of Kazakhstan grants the public the right to obtain information, including ecological information, public access to decision-making and justice. Although the legislation of the Republic of Kazakhstan both sectoral and general direction, there is legislative recognition, but need to develop specific procedures and mechanisms for their implementation, taking into account the provisions of the Convention.

[Tynybekov S., Yerezhepkyzy R., Berdibayeva A.K., Esekeeva A.A., Mynbatyrova N.K., Akopova E. Access to environmental information in legislation of the republic of Kazakhstan. Life Sci J 2014;11(5s):231-238]. (ISSN:1097-8135). http://www.lifesciencesite.com. 45

doi:10.7537/marslsj1105s14.45

Keywords: Aarhus Convention, the law, the right of access to ecological information, public, ecological protection, public access to decision-making and justice

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The concept, value, and the procedural position of defense attorney at the preliminary investigation

Serikkali Tynybekov¹, Ermek Talantuly Nurmaganbet ², Lyazzat Malkaidarovna Duysenova³

¹Al-Farabi Kazakh National University

²Al-Farabi Kazakh National University of on scientific and innovative activity and international relations

³Kazakh State Women's Teacher Training University

Abstract. In article on the basis of the analysis of the legislation of the RK and some foreign countries about lawyer activity and legal profession, provisions Constitution of RK Criminal Procedure Code and the Law of RK “About lawyer activity” and scientific literature author considers a question of a concept "the professional rights of the lawyer defender". The article examines the effectiveness of the exercise of advocate's powers, depending on procedural guarantees fixed in law. The author researches the meaning and the role of procedural position of the defense attorney and notes that the position should be developed for proper exercise of advocate's powers in criminal proceedings. The scientific-practice work analyses requirements of quality of professional defense in criminal cases. If still recently these requirements were of more part the internal norms of professional ethics of the lawyer's community, now there are the real legal imperatives. The article analyses the provisions of some Codes of Professional Ethics, opinions of some researchers, provisions of legislation, basic issues of ethic of representatives of advocatory, ways of negotiation of the existing problems.

[Tynybekov S., Nurmaganbet E.T., Duysenova L.M. The concept, value, and the procedural position of defense attorney at the preliminary investigation. Life Sci J 2014;11(5s):239-247]. (ISSN:1097-8135). http://www.lifesciencesite.com. 46

doi:10.7537/marslsj1105s14.46

Keywords: advocate, ethics, criminal procedure, code of ethics, advocate chambers.

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Clinical and pathologoanatomic description of hen’s organs in response to introduction of inactivated vaccines against pasteurellosis of birds

Mynbay Umitzhanov¹, Utegen Bairgalievich Taubaev², Kaisar Zhalitovich Kushaliev²

¹“Kazakh Scientific Research Veterinary Institute”, Raiymbek prospect, 223, Almaty, 050016, Kazakhstan

²“West Kazakhstan Agro-technical University named after Zhangir khan”, Zhangir Khan 51, Uralsk, 090009, Kazakhstan

Abstract. The results of proposed inactivated vaccine effect to internal organs of the hens and clinic- patholoanatomic change in internal and other organs are described in the paper. The Analysis of the sectional material of a year-old hens, immunized by inactivated vaccine against pasterellosis of birds, harmlessness, absence of pronounced clinic-pathologic manifestations both of local and general character in organs and tissues should be noticed. It is established that in immunocompetent organs: spleen and thymus, their size on the first 7 days is increased after immunization without deep destructive changes.

[Umitzhanov M., Taubaev U.B., Kushaliev K.Z. Clinical and pathologoanatomic description of hen’s organs in response to introduction of inactivated vaccines against pasteurellosis of birds. Life Sci J 2014;11(5s):248-250]. (ISSN:1097-8135). http://www.lifesciencesite.com. 47

doi:10.7537/marslsj1105s14.47

Keywords: immunegenesis, immune status, immunological changes in the body, change, analysis, injection, vaccine.

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Microstructural changes in the body of chickens in response to the introduction of liquid inactivated vaccine against pasteurellosis of birds

Mynbay Umitzhanov¹, Utegen Bairgalievich Taubaev², Kaisar Zhalitovich Kushaliev²

¹“Kazakh Scientific Research Veterinary Institute”, Raiymbek prospect, 223, Almaty, 050016, Kazakhstan

²“West Kazakhstan Agro-technical University named after Zhangir khan”, Zhangir Khan 51, Uralsk, 090009, Kazakhstan

Abstract. The article presents the effect of the proposed vaccine on the internal organs of chickens and histological study in microsections of spleen, liver, kidneys and other organs. Thus, the PROTECTIVE vaccine made of Pasteurella with optimal ratios of biochemical ingredients, prepared on the basis of polypotent, protein-carbohydrate, enzymatic medium adding adjuvant immunomodulator in the body of yearling hens, caused moderate immunomorphological reactivity and showed high protective properties by intramuscular injection at a dose of 1,0 cm³. Immune mechanisms due to the vaccine, were showed in organs in the dynamics with activation of macrophage, hyperplastic and plasma reactions throughout the observation period.

[Umitzhanov M., Taubaev U. B., Kushaliev K.Z. Microstructural changes in the body of chickens in response to the introduction of liquid inactivated vaccine against pasteurellosis of birds. Life Sci J 2014;11(5s):251-254]. (ISSN:1097-8135). http://www.lifesciencesite.com. 48

doi:10.7537/marslsj1105s14.48

Keywords: Vaccine, microstructure, mikrosrezy, immune system, immunization, histoarchitectonics

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“Muslim schools and madrasahs in new tendency” on the basis of Islam culture in Bukey Horde reformed by Zhanghir khan

Yerkin Sagyntayuly Ayagan, Sara Khamitovna Mediyeva, Jannur Bahytovna Asetova

Karaganda State University named after Y.A. Buketov, Universitetskaya Street, 28, Karaganda, 100028, Republic of Kazakhstan

Abstract. This article examines how the wise management of Zhanghir khan in Bukey Horde deals with the problems of education in State level. Zhanghir khan aimed to take up this problem in Bukey Horde through diplomatic relationships with tsarist Russia. Therefore, schools and madrasahs in new tendency on the basis of Islam culture in Kazakh land firstly were introduced in Bukey Horde. In this state policy of Zhanghir khan the system of religious education on the content of knowledge of new tendencies were taught to young generation and there is some information how linked Kazakh cultural heritage and ethno pedagogical values in Islam culture leaked to educational process. Also, humanity and religious education in pedagogical ideas and thoughts of outstanding philosophers are analyzed. The usage of these ethno pedagogical values to rear young generation in religious and patriotic process in modern educational branch is widely talked.

[Ayagan Y. S., Mediyeva S.K., Asetova J.B. “Muslim schools and madrasahs in new tendency” on the basis of Islam culture in Bukey Horde reformed by Zhanghir khan. Life Sci J 2014;11(5s):255-258] (ISSN:1097-8135). http://www.lifesciencesite.com. 49

doi:10.7537/marslsj1105s14.49

Keywords: Kazakhstan, Bukey Horde, Zhanghir khan, Islam culture, Muslim schools, madrasahs, religious education, Kazakh ethnic education, tsarist Russia, schools in new tendency, religious knowledge of Khodja Akhmet Yassawi.

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About increase of efficiency of vocational training of students

Zhanar Baigozhina¹, Guldana Zhakibayeva¹, Janat Zhantemirovich Sakenov¹, Nadezhda Zavalko², Zhanat Zholdybaevna Nurtayeva³, Gulnara Turlybekovna Tasbulatova⁴

¹Pavlodar State Pedagogical Institute, Pavlodar, Kazakhstan

²East Kazakhstan State University named S.Amanzholov, Kazakhstan

³Kazakh Humanities and Law University, Kazakhstan

⁴Department for Control of Education Akmola region, Kokshetau, Kazakhstan

Abstract. In article need of increase of efficiency of vocational training of students in the tideway of a tendency of development of modern pedagogical activity and professional education (transition to multilevel education, a tendency to integration locates in education, ensuring functional literacy of graduates, attention strengthening to the culturological content of vocational training). Efficiency of realization of pedagogical conditions of increase of efficiency of vocational training of students comes to light on the basis of criteria of professional readiness as result of this preparation, including: motivational criterion and indicators: enthusiasm for informative activity, orientation to future professional activity, aspiration to creative self-realization; substantial criterion and indicators: formation of professional knowledge and abilities; formation of professional independence; activity criterion and indicators: ability to carry out introspection, self-image and self-correction of vocational training.

[Baigozhina Z., Zhakibayeva G., Sakenov J.Z., Zavalko N., Nurtayeva Z. Z., Tasbulatova G.T. About increase of efficiency of vocational training of students. Life Sci J 2014;11(5s):259-262] (ISSN:1097-8135). http://www.lifesciencesite.com. 50

doi:10.7537/marslsj1105s14.50

Keywords: vocational training of students, increase of efficiency of vocational training of students

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Micro- and nanogold in the auriferous of weathering crusts of Martovskoye and Ravninnoye deposits (west Kazakhstan)

Kulyash Sharanovna Dyussembayeva, Adilkhan Bekdildaevich Baibatsha, Aymkhan Turapbayevna Kassenova, Saltanat Kalykbaevna Assubayeva

Kazakh National Technical University named after K.I. Satpayev, Satpaev st., 22, Almaty, 050013, Republic of Kazakhstan

Abstract. Mineral composition of the ores of Martovskoye and Ravninnoye deposits in weathering crusts are studied to prepare them for mining by heap leaching. Microscopic study of ores involving highly precise methods revealed micro-and nano-gold associated with limonite zones. Nanogold is presented in the form of unusual branchy formations. When the deposit will be practiced are possible losses of gold because of the presence micro-sized gold particles on the border with nanoscale. In this connection it is necessary to pay close attention to their presence in the weathering crust.

[Dyussembayeva K.S., Baibatsha A.B., Kassenova A.T., Assubayeva S.K. Micro- and nanogold in the auriferous of weathering crusts of Martovskoye and Ravninnoye deposits (west Kazakhstan). Life Sci J 2014;11(5s):263-266] (ISSN:1097-8135). http://www.lifesciencesite.com. 51 

doi:10.7537/marslsj1105s14.51

Keywords: deposit, mineral, gold, micro, nanoscale, heap leaching, crust

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The course "Morphology of Plants" as means of activization of students – biologists’ self-education

Bakhytzhamal Bagustarovna Gabdulhaeva, Muhametkali Kalimovich Zhakupov, Gulsara Kanatkyzy Darzhuman, Saltanat Zhumabaevna Kabieva, Bibenur Askarovna Baidalinova

Pavlodar State Pedagogical Institute, Pavlodar, Kazakhstan

Abstract. In article the essence of self-education of students-biologists on the basis of the theoretical analysis of a readiness of a problem in the theory and practice is defined. Self-education of students biologists is a process and result of development in students biologists of abilities of statement of a self-educational educational task; realization of self-educational educational actions and operations; self-checking behind a course of the solution of a self-educational educational task and self-image of result. The course "Morphology of Plants" locates in work as means of activization of students – biologists’ self-education. The Model of self-education of students-biologists taking into account pedagogical conditions of its activization is developed through the course "Morphology of Plants".

[Gabdulhaeva B.B., Zhakupov M.K., Darzhuman G.K., Kabieva S.Z., Baidalinova B.A. The course "Morphology of Plants" as means of activization of students – biologists’ self-education. Life Sci J 2014;11(5s):267-271] (ISSN:1097-8135). http://www.lifesciencesite.com. 52

doi:10.7537/marslsj1105s14.52

Keywords: self-education of students biologists, pedagogical conditions of activization of self-education of students biologists, the course "Morphology of Plants", as means of activization of students – biologists’ self-education.

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Pedagogical conditions of formation of students research culture (linguistic aspect)

Anar Bauyrzhanovna Ibrayeva¹, Khadisha Serekpayevna Omarova¹, Salima Amerzhanovna Urazbayeva¹, Aiman Berikpayevna Sarsembayeva², Janat Zhantemirovich Sakenov³

¹Kazakh Humanities and Law University, Astana, Kazakhstan

²Institute of Diplomacy, Academy of Public Administration under the President of the Republic of Kazakhstan

³Pavlodar State Pedagogical Institute, Pavlodar, Kazakhstan

Abstract: In article the linguistic aspect of formation of students research culture as purposeful process of realization of potential possibilities locates in linguistic development and transformation of the scientific world, proceeding in specific conditions of the linguistic educational environment. Using of possibilities of linguistics in educational process - one of conditions of formation of students research culture which substantial components are: research competence; development of creative qualities and abilities; valuable relation to the linguistic environment. In work the Model of formation of students research culture, with a support on linguistic aspect in training where the system of cooperating structural elements are presented, such as the purposes, criterion, indicators, pedagogical conditions is offered.

[Ibrayeva A. B., Omarova K.S., Urazbayeva S.A., Sarsembayeva A.B., Sakenov J.Z. Pedagogical conditions of formation of students research culture (linguistic aspect). Life Sci J 2014;11(5s):272-275] (ISSN:1097-8135). http://www.lifesciencesite.com. 53 

doi:10.7537/marslsj1105s14.53

Keywords: pedagogical conditions of formation of students research culture, linguistic aspect of formation of students research culture.

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The influence of phytomedicine on the condition of lipid peroxidation in immunocompetent organs and tissues of irradiated organism

Oralbek Ilderbayev, Ainur Argynbekova, Nazym Kudaibergenova, Asylzhan Mesova, Meruyert Mukasheva, Darkhan Uzbekov, Bakytbek Sovetov, Karlygash Kaliekova

Semey State Medical University, Abay str., 103, Semey, 071400, Kazakhstan

Abstract. The animals were exposed to ionizing radiation (gamma-radiation ⁶⁰Co) on the radiotherapeutic equipment “Teragam” in a dose of 6 Gy and received phyto medicine Epb in a dose of 35 mg/kg orally within 14 days following the ionizing radiation exposure. Gamma-rays caused the increase of lipid peroxidation (LPO) primary (CD-conjugated dienes) and secondary products’ (MDA-malonic dialdehyde) concentrations in spleen, liver, thymus and adrenal glands. Treatment by phytomedicine Epb resulted in contents of conjugated dienes decreased in 3.3 times in spleen, in 7.3 times in thymus, in 5.2 times in adrenal glands, in liver in 4.71 times, in lymph nodes of small intestine it in 3.69 times. Malonic dialdehyde decreased in liver up to 6.2 and 3.78 times, in spleen in 3.3 times, in thymus in 9.5 times, in liver in 6.21 times, in adrenal glands in 12.6 time, no changes in lymph nodes of small intestine. Conclusions: The effect of Epb phytomedicine treatment of organisms exposed to sublethal dozes of gamma-radiation results in the LPO primary and secondary products concentrations decrease in spleen, liver, thymus and adrenal glands.

[Ilderbayev O., Argynbekova A., Kudaibergenova N., Mesova A., Mukasheva M., Uzbekov D., Sovetov B., Kaliekova K. The influence of phytomedicine on the condition of lipid peroxidation in immunocompetent organs and tissues of irradiated organism. Life Sci J 2014;11(5s):276-279] (ISSN:1097-8135). http://www.lifesciencesite.com. 54

doi:10.7537/marslsj1105s14.54

Keywords: phytomedicines, radiation, lipid peroxidation.

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Role of biological disciplines in formation of professional competence of future teacher of biology

Saltanat Zhumabaevna Kabieva, Zhanat Makanovna Mukataeva, Alma Shakuovna Toktarbaeva, Gulnar Kairzhanovna Syzdykova, Natalya Petrovna Korogod

Pavlodar State Pedagogical Institute, Pavlodar, Kazakhstan

Abstract. In article the role of biological disciplines locates in formation of professional competence of future teacher of biology in the conditions of upgrade modern pedagogical education. As a theoretical and methodological basis of formation of professional competence of future teacher of biology the competitive approach to construction and research of the educational processes, considering problems of readiness for professional activity is offered. Process of formation of professional competence of future teacher of biology during studying the biological disciplines which essence consists in mastering by professional competences of areas of the educational, research, organizational, social, educational and technological activity, and necessary for work of the teacher of biology locates. Ability to use this biological knowledge locates in professional activity of future teacher of biology for the solution of problems of the biological education considering specifics of specialty biology Professional competences of future teacher of biology from a position of formation of knowledge of biological disciplines.

[Kabieva S.Z., Mukataeva Z.M., Toktarbaeva A.S., Syzdykova G.K., Korogod N.P. Role of biological disciplines in formation of professional competence of future teacher of biology. Life Sci J 2014;11(5s):280-284] (ISSN:1097-8135). http://www.lifesciencesite.com. 55 

doi:10.7537/marslsj1105s14.55

Keywords: professional competences of future teacher of biology, a role of biological disciplines of formation of professional competence of future teacher of biology.

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The contemporary condition of specially protected natural reservations in Aktobe Region of the republic of Kazakhstan

Asyma Galimzhankyzy Koshim¹, Aigul Мaksatovna Sergeyeva², Akzhunus Gafurovna Abdullina², Miras Amangeldievich Galimov³

¹Al-Farabi Kazakh National University, Al-Farabi Avenue, 71, Almaty, 050040, Republic of Kazakhstan

²K. Zhubanov Aktobe Regional State University, Moldagulova Ave, 34, Aktobe, 030000, Republic of Kazakhstan

³Makhambet Utemisov West Kazakhstan State University, Dostyk street, 162, Uralsk, 090000, Republic of Kazakhstan

Abstract. Over the long history of mankind there is an increase of anthropogenic load on natural systems. This load transforms the environment to a greater or lesser extent. In compliance with the law, the main question concerning specially protected natural reservations is to preserve the biodiversity through the conservation of natural habitats. In this regard, the protected areas interconnected by ecological and migration corridors form regional and global networks. These networks are the principal tool for preserving and restoring biodiversity. All types of landscapes within the boundaries of the area have the same scientific and practical conservation value. The article contains the characteristic of landscapes according to their prevalence in the area. This was done for easier analysis of contemporary condition and the validity of the proposals for the structure of specially protected natural reservations of Aktobe Region.

[Koshim A. G., Sergeyeva A.М., Abdullina A.G., Galimov M.A. The contemporary condition of specially protected natural reservations in Aktobe Region of the republic of Kazakhstan. Life Sci J 2014;11(5s):285-288] (ISSN:1097-8135). http://www.lifesciencesite.com. 56 

doi:10.7537/marslsj1105s14.56

Keywords: specially protected natural reservations, natural reserve, zonal landscape, environmental framework, azonal landscape, intrazonal landscape, conservation of biodiversity.

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Traditional Dance Culture of Ethnos - the Basis of Ethno-Choreographic Education (by the Example of Kazakh Dance)

Aigul Kenesovna Kulbekova

Kazakh National University of Arts, Tauyelsyzdykave, 50, Astana, 010000, Kazakhstan

Abstract. In the article, the author deals with the development process of ethno-choreographic education in Kazakhstan. In the modern period of development of choreographic pedagogics, a shift from the study of the bases of Kazakh folk choreography, genesis, traditional culture of ethnos to the method of execution shall be carried out within the frames of two constituents: assimilation of national choreographic heritage and modern achievements of Kazakh dance plastics. Based on the analysis of different author's training procedures for Kazakh dance, the tasks of ethno-choreographic education development were determined. Based on the study of scientific works of Russian and Kazakh researchers, ethnographers, the ancient existence of dance culture in Kazakh society was substantiated and proved, and the content of pedagogical training technologies for national choreography specialists was revealed.

[Kulbekova A.K. Traditional Dance Culture of Ethnos - the Basis of Ethno-Choreographic Education (by the Example of Kazakh Dance). Life Sci J 2014;11(5s):289-291] (ISSN:1097-8135). http://www.lifesciencesite.com. 57

doi:10.7537/marslsj1105s14.57

Keywords: ethno-choreographic education, traditional culture, ethnos, choreographic heritage, training procedure, Kazakh dance.

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Formation of moral values of schoolchildren by means of Kazakh folklore

Gulmira Mailybaeva, Danyar Utegulov, Smagulova Guldarhan, Rakhimova Aina, Chukenaeva Gulim

Zhetysu State University named after I.Zhansugurov, Zhansugurov str., 187а Таldykorgan, 040000, the Republic of Kazakhstan

Аbstract. Formation of moral values of young schoolchilden by means of Kazakh folklore is studied in the article. At the modern development of Kazakhstan, community has faced number of new scientific and practical tasks that require deep understanding of historical place and role of folklore in the integrated social life and cultural production, with its specific forms and functions. Moral education is one of the urgent problems in many countries of the world, therefore we have paid attention not only to gained experience we have, but also identified the theoretical basis of formation of valuable relationships of young schoolchildren, we have clarified the content and essence of the concepts of “value” and “valuable relations”.

[Mailybaeva G., Utegulov D., Guldarhan S., Aina R., Gulim C. Formation of moral values of schoolchildren by means of Kazakh folklore. Life Sci J 2014;11(5s):292-295] (ISSN:1097-8135). http://www.lifesciencesite.com. 58 

doi:10.7537/marslsj1105s14.58

Keywords: moral, moral values, Kazakh folklore, proverbs, puzzles, fairy tales.

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New data on the ecology of the Northern Aral Sea after the construction of the first Kokaral dam on the Berg Strait

Ayzhigit Mambetovich Nurgizarinov, Anipa Seydalevna Tapalova, Essenzhol Assylbekuly Nazarov, Akmaral Zhunisovna Sharipova

Kyzylorda State University named after Korkyt Ata, Ualieva str. 22/88, Kyzylorda, Kazakhstan

Abstract. The authors of this article "New data on the ecology of the Northern Aral Sea after the construction of the first dam on the sea Kokaral Berg Strait", devoted to the Northern Aral Sea, which was separated from the large sea Aral recently as "assignee" of itself. Based on my research and observations the authors have collected enough compelling material on the state ecology small Aral, its influence on the formation of biological resources. The authors believe that the small Aral ennobling influence on the environment is undeniable, because there is still performs the second stage of the project RSRNAS. Article was written in a simple form, convincingly.

[Nurgizarinov A.M., Tapalova A.S., Nazarov E.A., Sharipova A.Z. New data on the ecology of the Northern Aral Sea after the construction of the first Kokaral dam on the Berg Strait. Life Sci J 2014;11(5s):296-299] (ISSN:1097-8135). http://www.lifesciencesite.com. 59 

doi:10.7537/marslsj1105s14.59

Keywords: The Aral Sea, Aklak, Syrdarya, RSRNAS, Ecology, restoration, fish fauna, aquatic resources, Butakov, Sarchaganak, desiccated, Karateren.

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Modeling of traffic flows with due regard to ecological criteria 

Saken Sadibekovich Pernebekov¹, Zhenis Abzhanovich Sadykov¹, Askar Aldabergenuly Meiirbekov¹, Dinara Riskulbekovna Tortbayeva¹, Irina Viktorovna Makarova², Rifat Gabdulhakovich Khabibullin², Eduard Irekovich Belyaev², Ilnar Fargatovich Suleimanov² 

¹Transport, organization of transportation and vehicular traffic of M.Auezov South Kazakhstan State University, Shymkent city, Kazakhstan

²Kazan Federal University, Syuyumbike Ave., 10A, Naberezhnye Chelny, 423812, Republic of Tatarstan, Russia 

Abstract. The article deals with issues of ensuring the reliable and safe city transport system operation through the use of the rational management methods. To make evidence-based management decisions are encouraged to use worked out intelligent decision support system. It is shown that a comprehensive solution of the city transport system management contributes to the sustainable development of the region.

[Pernebekov S.S., Sadykov Z.A., Meiirbekov A.A., Tortbayeva D.R., Makarova I.V., Khabibullin R.G., Belyaev E. I., Suleimanov I. F. Modeling of traffic flows with due regard to ecological criteria. Life Sci J 2014;11(5s):300-302] (ISSN:1097-8135). http://www.lifesciencesite.com. 60 

doi:10.7537/marslsj1105s14.60

Keywords: sustainable development, transport, ecology, intellectual transport systems (ITS), simulation.

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The establishment of specialized environmental court in the republic of Kazakhstan – call of the times 

Zhadyra Slamhanovna Shukenova¹, Bolat Zholdasbekovich Aitimov², Bolat Abduldaevich Seriyev² 

¹H.А. Yasawi International Kazakh-Turkish University, Kazakhstan

²I.Zhansugurov Zhetysu State University, Kazakhstan 

Abstract. The article considers the legal protection of the environment and analyzes the development of the environmental legislation. Resolution of issues of combination of economic and ecological interests of society and state in the process of law-making is important for conduct of ecological policy favorable for the citizens of RK. The article states that only state regulations allows to decide the problem in complex. By consideration of problems of the environmental legislation, questions of imperfection of norms ecological law are mentioned. The author considers the possibility of forming a system of environmental courts, and also raises the question of the necessity of its creation. The article gives reasons for the creation of special environmental courts in RK. The main limiting factor on the way of creation of environmental courts is the necessity of additional financing. It may be negotiated on the basis of use of foreign and international experience.

[Shukenova Z.S., Aitimov B.Z., Seriyev B.A. The establishment of specialized environmental court in the republic of Kazakhstan – call of the times. Life Sci J 2014;11(5s):303-310] (ISSN:1097-8135). http://www.lifesciencesite.com. 61 

doi:10.7537/marslsj1105s14.61

Keywords: ecological law, environmental legislation, society, state, environmental courts

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The retroactive force of criminal laws in the system of general principles for their action in time

Marat Zholumbayev, Daniyar Nurmukhanbet, Kuralay Zhumabayeva, Laura Satybaldi, Gulden Seisembayeva, Umsyn Tleuberdina, Dinara Mussipova

Abay Myrzakhmetov Kokshetau University, M. Auezov Street, 189a, Kokshetau, 020000, Republic of Kazakhstan

Abstract. This article is dedicated to topical aspects of applying the principle of the retroactive force of the criminal laws of Republic of Kazakhstan. On the strength of the study of views held by different scientists and comparative analysis of the practice of applying the criminal code, the author puts forth recommendations and suggestions on streamlining existing legislation. Amid the adoption of new criminal legislation, the criminal-legal institute under study takes on special significance in the system of norms of the General and Special parts of the Criminal Code.

[Zholumbayev M., Nurmukhanbet D., Zhumabayeva K., Satybaldi L., Seisembayeva G., Tleuberdina U., Mussipova D. The retroactive force of criminal laws in the system of general principles for their action in time. Life Sci J 2014;11(5s):311-315] (ISSN:1097-8135). http://www.lifesciencesite.com. 62 

doi:10.7537/marslsj1105s14.62

Keywords: criminal law, crime, retroactive force of laws, coming into effect, bringing into effect

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Formation at students of competence of use of an interactive board in work practice

Akzhan Myrzakadyrovna Abdykhalykova¹, Nazigul Nurlanovna Zhanakova¹, Dauren Esbolovich Tekebayev², Karlygash Tastanbekova², Zhanar Baigozhina³, Janat Zhantemirovich Sakenov³, Gulzhan Muhametkalievna Gauriyeva⁴

¹ Kazakh University of Economics, Finance and International Trade, Astana, Kazakhstan

²Kazakh Academy of Engineering and Technology, Astana, Kazakhstan

³Pavlodar State Pedagogical Institute, Pavlodar, Kazakhstan

⁴Eurasian National University named after L. Gumilev, Astana, Kazakhstan

Abstract. In article formation process at students the competence of using an interactive board theoretically locates in work practice. The formation Model at students of competence of use of an interactive board in work practice is developed. Methodical ensuring process of formation at students the competence of using an interactive board in work practice is developed. Criteria, indicators, levels of efficiency of process of formation at students of competence of use of an interactive board in work practice are defined. The pilot research is conducted and the efficiency of offered Model of formation at students the competence of using an interactive board in work practice is checked.

[Abdykhalykova A.M., Zhanakova N. N., Tekebayev D.E., Tastanbekova K., Baigozhina Z., Sakenov J.Z., Gauriyeva G.M. Formation at students of competence of use of an interactive board in work practice. Life Sci J 2014;11(5s):316-320] (ISSN:1097-8135). http://www.lifesciencesite.com. 63 

doi:10.7537/marslsj1105s14.63

Keywords: interactive board, formation at students the competence of using an interactive board in work practice.

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Economics of Azerbaijan: upgrading and implementation of effective instruments

Shafa Tiflis Aliyev

Sumgait State University, Badalbayli str., AZ 5008, Sumgait, Azerbaijan

Abstract. The topical issues of economics of Azerbaijan Republic, in particular the upgrading issues and importance of implementation of the up to date economic instruments in the economic system of the country are investigated in the article. There are also analyzed and validated the necessity of acceleration of the innovation of the economics in Azerbaijan, acquisition of the innovation activity, creation of network of the competitive enterprises, additional motivation in getting hold of large capital into the country from outside and attraction of investors to the oil sector, the activation of implementation of the new economic manners in the economic system of the country including the creation and functioning of the special economic zones.

[Aliyev S.T. Economics of Azerbaijan: upgrading and implementation of effective instruments. Life Sci J 2014;11(5s):321-326] (ISSN:1097-8135). http://www.lifesciencesite.com. 64 

doi:10.7537/marslsj1105s14.64

Keywords: Azerbaijan, macroeconomics, economics system, innovation, competitiveness, special economic zones, technology park.

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Advanced integrative definition of phenomenon lie (or deception) in psycholinguistics

Aigul Nazirovna Baituova, Rustam Ashimov, Ramilya Berdalieva, Zhazira Isaeva, Gulzada Abil

H.A.Yasawi International Kazakh-Turkish University, B. Sattarkhanov Avenue 29, Turkistan town, the main campus, 161200, Kazakhstan

Abstract. Lie and deceit have high psychological, speech and social importance, consideration of these phenomena in intercultural communication plays an important role nowadays. Phenomena of lies and deceptions become the subject of research in various fields of science in recent years. On the basis of a systematic structural descriptions of lies and deception speech can confidently predict the emergence of a new research direction in the world - «linguistics lies." Its subject should be considered false speech acts and psychological symptoms. Lies and deception affect the diversity and richness of forms. Lies are fixed by language, tools designed to serve as a communication tool by which human thought is formed and expressed. Lying is a phenomenon of verbal communication, which consists of deliberately distorting the actual state of affairs.

[Baituova A.N., Ashimov R., Berdalieva R., Isaeva Z., Abil G. Advanced integrative definition of phenomenon lie (or deception) in psycholinguistics. Life Sci J 2014;11(5s):327-330] (ISSN:1097-8135). http://www.lifesciencesite.com. 65 

doi:10.7537/marslsj1105s14.65

Keywords: lie, deceit, psycholinguistics, linguistics, society, a phenomenon illocution, per locution, integrative.

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Influence of migratory processes on change of Ethno demographic structure of Southern Kazakhstan population

Klara Baitureyeva and Bakhyt Saparbayev

South Kazakhstan State University named M. Auezov, Tauke Khan Avenue 5, Shymkent, Kazakhstan

Abstract. One of the basic conditions of progressive development of a mankind civilization is preservation of stability both in separately taken state and in the world as a whole that is represented impossible without upbringing of the tolerant relation to multiple manifestations of the most various processes occurring in a modern society. One of the important processes are ethno cultural processes and without understanding of the reasons of processes and phenomena characteristic for the present, it is impossible to understand what potential has in itself a modern society, to foresee a situation in sight as a whole. Problems of the social nature of growth and population development get the increasing urgency now. They are included in the United Nations in the list of 13 global problems of the present on which decision the destiny of all mankind depends. According to the importance the questions of ethno demographic development take the third place after a problem of war and peace, preservation of the environment. The demographic factor, along with social and national, also dominates in development of any forms of world civilization. Therefore without scientific analysis at all levels it is impossible to make real forecasts of political, economic and social development of the country and its regions.

[Baitureyeva K., Saparbayev B. Influence of migratory processes on change of Ethno demographic structure of Southern Kazakhstan population. Life Sci J 2014;11(5s):331-336] (ISSN:1097-8135). http://www.lifesciencesite.com. 66 

doi:10.7537/marslsj1105s14.66

Keywords: Kazakhstan, ethnos, demography, migration, ethno demographic development

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The new methodical system of creative thinking of students V-VI grades 

Zhamila Dzhaybulovna Dzhartybayeva¹, Aigerim Kusanovna Musakulova¹, Bakhtiyar Fayzullayevich Akhanov², Dariga Akhanova³ 

¹South-Kazakhstan State University named after M.Auezov, Boulevard of Tayke khan, 5, Shymkent, 160000, Kazakhstan

²Kokchetau University named A.Myrzahmetov, Boulevard of D.Konaeva, 31/9, Shymkent, 160000, Kazakhstan

³Boarding school "Art" for gifted children named B.Otep, microregion Sever, w/n, Shymkent, 160000, Kazakhstan 

Abstract. In the article discusses the main features of children's creativity, formation of creative thinking and problem, identifying the condition to ensure the maximum and comprehensive development of creative thinking, aspects of the formation of creative thinking of student’s grades 5-6 in the process of drawing from life. Pedagogical conditions for the development of creative thinking in the process of drawing from life, the foundations of how to promote creative person pupils'health, knowledge of the inner world of man, his spiritual formation and creative self-improvement.

[Dzhartybayeva Z.D., Musakulova A.K., Fayzullayevich A.B., Akhanova D. The new methodical system of creative thinking of students V-VI grades. Life Sci J 2014;11(5s):337-340] (ISSN:1097-8135). http://www.lifesciencesite.com. 67 

doi:10.7537/marslsj1105s14.67

Keywords: creative thinking, creativity, activity, ability, intellectual and creative potential, harmoniously, staging, drawing from nature, ability.

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Modeling of agent technology at computing option of flexible manufacture system element and composes structure

Aqil Hamid Huseynov

Sumgait State University, kvartal 43, Sumgait, Az 5004, Azerbaijan 

Abstract. At present by investigation of the problems of computing design of flexible manufacture system (FMS), specialty on the beginning stages, it is necessary to do purpose-directly option of elements, informing data and parameters FMS. Computing option of FMS, as complex iteration process, is performed with many level organization of design procedures from design demands at first level to design solution of the demanded degree of detailing at the next levels. At computing option of FMS, for creation its informing, mathematical, program supports, the levels of logical and parametric designing application are demanded. In this connection, for designing process advancement of efficiency and accuracy, in the paper the problem of computing option and definition of FMS elements parameters on logical and parametric designing levels with agent’s technology application.

[Huseynov A.H. Modeling of agent technology at computing option of flexible manufacture system element and composes structure. Life Sci J 2014;11(5s):341-344] (ISSN:1097-8135). http://www.lifesciencesite.com. 68 

doi:10.7537/marslsj1105s14.68

Keywords: CAD, agent technology, flexible manufacture system, knowledge

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On the implementation of article 20 of the United Nations Convention against corruption into the criminal legislation of the Republic of Kazakhstan

Zhanat Askarovna Mamitova

“The Academy of the Financial Police” Public Institution, Post off. box 53, Central post office, Astana, 010000, Kazakhstan

Abstract. This article explores the essence of and issues in the implementation of international legal norms into Kazakh legislation. The author conducts a comparison of the way the norms on illicit enrichment are interpreted in the legislation of particular foreign countries, which makes it possible to reveal weaknesses in Kazakh criminal law. Based on the study conducted, the author puts forth suggestions on criminalizing the article and bringing it in line with the norms of the UN Convention against Corruption (the United Nations Convention), which is dedicated to illicit enrichment, as well as ways of improving the effectiveness of the mechanism of implementing the norms of international criminal law into national criminal legislation.

[Mamitova Z.A. On the implementation of article 20 of the United Nations Convention against corruption into the criminal legislation of the Republic of Kazakhstan. Life Sci J 2014;11(5s):345-348] (ISSN:1097-8135). http://www.lifesciencesite.com. 69 

doi:10.7537/marslsj1105s14.69

Keywords: implementation, corruption, illicit enrichment, confiscation of property

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The role of pedagogical disciplines in formation of professional competence of future teacher

Baurjan Ablaevich Nurumov¹, Janat Zhantemirovich Sakenov¹, Ulbosyn Samethanovna Marchibayeva², Indira Bekenovna Imangalikova²

¹Pavlodar State Pedagogical Institute, Pavlodar, Kazakhstan

²Eurasian National University named after L. Gumilev, Astana, Kazakhstan 

Abstract. In the article the role of pedagogical disciplines locates in formation of professional competence of future teacher in the course of their professional training. The essence of formation of professional competence of future teacher consists in mastering professional competences of areas of educational, research, organizational, social and educational activity. The structure is developed, the contents, criteria and levels professional competences of future teacher are defined. The model of formation of professional competence of future teacher is developed. Efficiency of model of formation of professional competence of future teacher in the course of professional training is experimentally checked.

[Nurumov B.A., Sakenov J.Z., Marchibayeva U.S., Imangalikova I.B. The role of pedagogical disciplines in formation of professional competence of future teacher. Life Sci J 2014;11(5s):349-353] (ISSN:1097-8135). http://www.lifesciencesite.com. 70 

doi:10.7537/marslsj1105s14.70

Keywords: Formation of professional competences of future teacher, a role of pedagogical disciplines in formation of professional competence

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Future teachers training for application of the Kazakh ethno pedagogy means in the process of schoolchildren’s patriotic education

Galia Rysbayeva, Kulsara Makhmutova, Kairat Ibragim, Perizat Abasheva, Lyazzat Buletova, Zhuzira Kuatova, Zhamilya Munazhova, Timur Gapparov

South Kazakhstan State M.Auezov University, Tauke Khan 5, Shymkent, Kazakhstan

Abstract. The system of measures on development of scientific-theoretical and methodical bases of patriotic education provides: continuation of researches in sphere of patriotic education and use of their results in practical activity; working out of methodical recommendations on problems of formation and development of the patriot’s personality; working out of a complex of educational and special programs and techniques in the field of it; working out of model of realization of the basic directions of activity of the governmental institutes on patriotic education and its approbation; studying and compilation of the best practices in the field for its introduction in practice of patriotic work. Necessity of patriotic formation of growing up generation follows from the essence of process of education modernization.

[Rysbayeva G., Makhmutova K., Ibragim K., Abasheva P., Buletova L., Kuatova Z., Munazhova Z., Gapparov T. Future teachers training for application of the Kazakh ethno pedagogy means in the process of schoolchildren’s patriotic education. Life Sci J 2014;11(5s):354-358] (ISSN:1097-8135). http://www.lifesciencesite.com. 71 

doi:10.7537/marslsj1105s14.71

Keywords: new Kazakhstan patriotism, patriotic education, education modernization, ethno pedagogy

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Teaching methods of visual programming technology 

Beibytgul Koishievna Shayakhmetova^1, Sholpan Embergenovna Omarova², Gali Tulegenovich Omarov²

¹Karaganda State University of E.A. Buketov, Kazakhstan

²Karaganda Economic University of Kazpotrebsoyuz, Universitetskaya 28 street, Karaganda, 100028, Kazakhstan 

Abstract. In this article considered the modern direction in programming - it is a visual programming and also here considered the teaching methodology. Also it should be noted that visual programming based on objective-oriented ideas, it is the automated processing programs using special on-line processing. The most common visual programming interface is used to create a software and database management systems. This information technology in the education sphere based on the educational software.

[Shayakhmetova B.K., Omarova S.E., Omarov G.T. Teaching methods of visual programming technology. Life Sci J 2014;11(5s):359-361] (ISSN:1097-8135). http://www.lifesciencesite.com. 72 

doi:10.7537/marslsj1105s14.72

Keywords: visual programming technology, technology, method, interface, database.

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Mechanisms of effective integration of Kazakhstan in the world system and regulation of foreign trade activities in the conditions of globalization

Gulnar Urazbaeva¹, Katira Satimbekova¹, Dana Kulanova¹, Aigul Shadieva², Akmaral Demeubaeva², Galymzhan Kerimbek³, Zauresh Imanbayeva⁴, Altynsary Umbitaliev⁵

¹South Kazakhstan State University named after M. Auezov, Kazakhstan

² South Kazakhstan Institute of Humanities named after M. Saparbayev, Kazakhstan

³Eurasian National University named after L. Gumilev, Kazakhstan

⁴Aktobe Regional State University named after K. Zhubanov, Kazakhstan

⁵Institute of Economics of the University of Shymkent, Kazakhstan

Abstract. One of the major transformational processes, proceeding in Kazakhstan economy, is its integration into the world economy which occurs in the adequate way for the market - by means of foreign trade activities that renders essential continuously growing and contradictory enough influence on the most various parties of an economic and social life of a society. On the one hand, foreign trade activities allow solving the vital problems for the country, to ensure stability of a financial system, to provide certain rates of economic growth. On the other hand, foreign trade activities are burdened with serious problems: backward structure, fuel-raw orientation of export, low level of the organization, etc. It essentially reduces its efficiency, does not promote basic changes in national economy structure, to overcoming of the status of Kazakhstan as the country which are on periphery of geo-economics system. Kazakhstan realizes the given possibility, using available potential, increases foreign trade volumes, develop direct partner relations with foreign countries, and attract foreign investments. For realization of this process completely, the country should possess a wide range of necessary conditions, direct considerable efforts to improvement of competitive characteristics of the economic system, continuously improve foreign trade activities on the basis of realization of all riches, its content, harmonious development of its forms.

[Urazbaeva G., Satimbekova K., Kulanova D., Shadieva A., Demeubaeva A., Kerimbek G., Imanbayeva Z., Umbitaliev A. Mechanisms of effective integration of Kazakhstan in the world system and regulation of foreign trade activities in the conditions of globalization. Life Sci J 2014;11(5s):362-366] (ISSN:1097-8135). http://www.lifesciencesite.com. 73 

doi:10.7537/marslsj1105s14.73

Keywords: foreign trade activities, foreign investments, competitive positions, institutional forms, globalization.

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Evaluation of technical approaches of industrial policy

Dinara Yermekbayeva, Yekaterina Shishkina, Samat Yermukhan

University of International Business, Abai аve., 8 A, Almaty, 050010, Kazakhstan

Abstract. The article is devoted to the formation of industrial policy in Kazakhstan under the conditions of integration, and stresses the importance of such policy-making both in the country and by taking into account interaction with Common Economic Space (CES) countries. Performed analysis of works on the formation of industrial policy allows determine practical arguments in terms of the industrial policy methods and instruments. Analysis of several branches of industry has been accepted for the industrial policy evaluation. Application of analytical leveling-off technique allows determine physical quantities of industrial production in building in the future development plans. This method is effective in carrying out of medium term forecasts for the development of branch complexes, that is very important in periods of economy crisis.

[Yermekbayeva D., Shishkina Y., Yermukhan S. Evaluation of technical approaches of industrial policy. Life Sci J 2014;11(5s):367-371] (ISSN:1097-8135). http://www.lifesciencesite.com. 74 

doi:10.7537/marslsj1105s14.74

Keywords: industrial policy, innovative policy, engineering productions, analysis of branches, forecasting technique of building industry.

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Chapter I. Formation of Kazakh novel and creative work of Zh. Aimautov

Aiman Faizylovna Zeinulina^1,2, Bakyt Amirkhankyzy Yskak^1,2, Farida Tokanovna Zhumazhanova^1,2

¹Pavlodar State University named after S.Toraighyrov, Lomova Steet 64, Pavlodar, 140000, Kazakhstan

²al-Farabi Kazakh National University, al-Farabi ave 71, Almaty, 050040, Kazakhstan

Abstract. The article focuses on the Kazakh novel, in which he analyzed the new facets of artistic quest of the Kazakh writer. In Kazakh literature, the process of origination and establishment of the classical literature begins too. The start of the process of formation of Kazakh novel as a special genre of prose was put by the works: “Baqytsyz Jamal” by M. Dulatov, “Qyz koereligi” (Viewing of the Bride) by T. Zhomartbayev, “Qalyng mal” (Dowry) by S. Kobeyev, “Qamar sulu” by S. Toraigyrov. No doubt, these writers created these works and relied on those literary traditions that were learned by them in Russian and World Oriental Literature.

[Zeinulina A.F., Yskak B.A., Zhumazhanova F.T. Chapter I. Formation of Kazakh novel and creative work of Zh. Aimautov. Life Sci J 2014;11(5s):372-375] (ISSN:1097-8135). http://www.lifesciencesite.com. 75 

doi:10.7537/marslsj1105s14.75

Keywords: Zhusipbek Aimautov, W. Scott, V. Hugo, N. Gogol, M. Cervantes, H. de Balzac, G. Flaubert, H. Stendhal, Ch. Dickens, L. Tolstoy, I. Turgenev, connection, interdependence, Kazakh writers, Russian writers, works, written.

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Traditions and new tendencies of modern Kazakh literature development

Kuralay Zhanuzakova¹, Aynur Koshekova¹, Bolathan Sarbasov¹, Nargiza Baltabaeva¹, Gulzira Sagnaeva¹, Nurgul Medetbekova²

¹Kazakh National Women Pedagogical University, Kazakhstan

²South Kazakhstan State University M.Auezov, Kazakhstan

Abstract. At the end of the 20^th -at the beginning of the 21^st century Kazakhstan society enters a new stage of the development. The pluralism in the relation to earlier formed basic categories in a literature science (class character, socialist realism, etc.) opened a way to inconsistent sights in evaluation of history of the modern literature development. Together with change of perception of the literature role in a society, the active attitude to new forms, ways and means of the validity image the new scientific-theoretical approaches and principles of studying of literary process are fulfilled. Revealing of laws of the literature science development, determination of its methodological concepts, theoretical bases and directions of research, achievements and prospects is rather actual problem.

[Zhanuzakova K., Koshekova A., Sarbasov B., Baltabaeva N., Sagnaeva G., Medetbekova N. Traditions and new tendencies of modern Kazakh literature development. Life Sci J 2014;11(5s):376-379] (ISSN:1097-8135). http://www.lifesciencesite.com. 76 

doi:10.7537/marslsj1105s14.76

Keywords: literary and art tendencies, social and cultural conditions, genre system of criticism, postmodernism

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The unity of the language and cognition

Sayan Zhirenov¹, Ulzharkyn Abdigapbarova¹, Akmaral Smanova¹, Abdykalyk Kosherbayevich Abdillayev², Sara Вakhtiyarova³

¹ Abai Kazakh National Pedagogical University, Dostyk Avenue 13, Almaty, 050000, Kazakhstan

²H.A.Yasawi International Kazakh-Turkish University, B. Sattarkhanov Avenue 29, Turkistan town, the main campus, 161200, Kazakhstan

³Korkyt Ata Kyzylorda State University

Abstract. There is a wide process of considering the language in interconnection with other scientific spheres in linguistics. The language is not only the means of relation, it is not the unit of appearing the thought, it is the means of that give possibility to cognate the truth world through language by its cognitive quality. The human being cognates the nature of the truth world and different phenomenon by implementing the mechanisms of language cognition according to such activity of the language. According to this, the description of researching the cognitive mechanisms (cognitive mechanisms) of the nature of the truth world of human being is the main actuality of cognitive linguistic direction of present linguistics by using language. From this point, the human being takes possibility to cognate the simple, scientific, poetic, aesthetic shape of the world by language.

[Zhirenov S., Abdigapbarova U., Smanova A., Abdillayev A.K., Вakhtiyarova S. The unity of the language and cognition. Life Sci J 2014;11(5s):380-384] (ISSN:1097-8135). http://www.lifesciencesite.com. 77 

doi:10.7537/marslsj1105s14.77

Keywords: lexical system, antonym, antinomy, antithesis, antiphrasis, antonymy, linguistic opposition, сontrast unit, cognition, cognitive.

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Speech of an average citizen of a Russian town

Tatyana Michaylovna Balykhina¹, Marina Sergeevna Netesina^1,2

¹Peoples’ Friendship University of Russia, Miklukho-Maklaya Street, 6, Moscow, 117198, Russia

²Moscow State University of Medicine and Dentistry after A.I. Evdokimov, Delegatskaya Street, 20, Moscow, 127473, Russia

Abstract. Speech of an average citizen of today Moscow is analyzed in the article. New trends in today speech of a city are mentioned: dynamic overcoming of existing traditions, adoption of novelties from spoken discourse. It is necessary to study the complex of motivations that provoke statements (releasing tense, making a person laugh, etc.), compile dictionaries that include “positive” conversational speech (other studies are prevailing new), cataloging of speech material that is yet in the state of “remark” in researches now, turn to study of priorities of Russian people as it is shown in the article.

[Balykhina T.M., Netesina M.S. Speech of an average citizen of a Russian town. Life Sci J 2014;11(5s):385-392] (ISSN:1097-8135). http://www.lifesciencesite.com. 78

doi:10.7537/marslsj1105s14.78

Keywords: speech of an average citizen, Moscow, “positive” conversational speech, Russian people

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Forming The Ecological Culture Of Younger Schoolchildren With The Use Of Innovative Technologies In The Educational Process

Talgat Abubakirovich Daniyarov, Bakhytzhan Kalzhanovich Mukhamedzhanov, Perizat Bayteshovna Ceytkazy, Mariyam Botaevna Zhazdykbaeva, Shakhizada Ismailovna Isakhova, Elmira Zhakhanovna Khalilaeva, Zhakypbek Aydarbekovich Kasymbekov, Alina Kuandykovna Bimaganbetova

Ahmet Yasawi International Kazakh-Turkish University, 29 B. Sattarkhanov Avenue, 161200 Turkistan, Kazakhstan.

bimaganbetova-alina@mail.ru, science@iktu.kz

Abstract. The article deals with the theoretical justification, development and experimental checking the system of forming the ecological culture of younger schoolchildren with the use of innovative technologies in the educational process. The authors determined the pedagogical conditions of efficiency of forming the ecological culture of the younger schoolchildren on the basis of use of innovative technologies providing integrity and continuity of the process developing and stimulating creative, informative-search activity and interests of children to ecology taking into account age, social, ethno-religious and nature-climate factors.

[Talgat Abubakirovich Daniyarov, Bakhytzhan Kalzhanovich Mukhamedzhanov, Perizat Bayteshovna Ceytkazy, Mariyam Botaevna Zhazdykbaeva, Shakhizada Ismailovna Isakhova, Elmira Zhakhanovna Khalilaeva, Zhakypbek Aydarbekovich Kasymbekov, Alina Kuandykovna Bimaganbetova. Forming The Ecological Culture Of Younger Schoolchildren With The Use Of Innovative Technologies In The Educational Process. Life Sci J 2014;11(5s):393-399] (ISSN:1097-8135). http://www.lifesciencesite.com. 79

doi:10.7537/marslsj1105s14.79

Key words: ecological culture, innovative technologies, ecocontent, the educational process, collective interaction, intercreation.

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Uterine Mycotic Flora in Healthy Buffaloes and Buffaloes with Reproductive Disorders

Salma Ismail¹, Mehdi chavoshi^2*, Jamal Hussaini², Shahrbanoo Malekshaabani²

¹Faculty of Science, University of Malaya (UM), Malaysia

²Faculty of Medicine, University Technology MARA (UiTM), Malaysia

Abstract: Buffalo’s uterine mycotic flora has not been studied too much yet. The aim of current study is to investigate fungi in uterine of healthy buffaloes with the history of uterine disorders like metritis. Uterine lavage was done in 100 buffaloes (50 healthy and 50 problematic). Samples were cultured in Subro Glucose agar medium and Chloramphenicol in 28℃for 2 weeks. For more identification of fungi, Corn Meal Tween 80 agar medium and Chapex dox agar were used. The data were analyzed by Chi-square test in SPSS software. Fungi colonies were isolated from 20% (10) and 26% (13) of healthy and problematic buffalo cows, respectively and the difference was significant (p<0.05). The most prevalent fungi in buffaloes with uterine disorders were Aspergillus fumigatus and Penicillium spp., respectively. Mucur was dominant in healthy uterine. Uterine disorders may predispose uterine mycotic infections in buffaloes and lead to subfertility.

[Salma Ismail, Mehdi chavoshi, Jamal Hussaini, Shahrbanoo Malekshaabani. Uterine Mycotic Flora in Healthy Buffaloes and Buffaloes with Reproductive Disorders. Life Sci J 2014;11(5s):400-402] (ISSN:1097-8135). http://www.lifesciencesite.com. 80

doi:10.7537/marslsj1105s14.80

Keywords: Buffalo, Uterine, Fungi, Infection, Mycotic flora

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In Vitro Cytotoxic Activity of Matricaria Chamomilla Root Extract in Human Breast Cancer Cell Line MCF-7

Ali Mohammad Kamali, Mohsen Nikseresht, Hamdollah Delaviz, Mehrzad Jafari Barmak, Mahsa Servatkhah, Maryam Tajali Ardakani, Reza Mahmoudi ^*

Cellular and Molecular Research Center. Yasuj University of Medical Sciences, Yasuj, Iran

^*Corresponding Author: rmahmoudi40@yahoo.com

Abstract: Breast cancer is among the most common causes of cancer deaths in women. Recently, phytochemicals and their effects on the prevention and treatment of cancer have drawn a lot of attention. According to previous research, Matricaria chamomilla is a source of phytochemicals that have anticancer effects. In this research, the cytotoxic effects of the hydroalcoholic extract of Matricaria chamomilla root on the MCF-7 breast cancer cell line were investigated. Materials and Methods: The MCF-7 cells were treated for 24, 48 and 72 hours with different concentrations (200-2000) of Matricaria chamomilla root extract in DMEM (Dulbecco’s Modified Eagle’s Medium) culture medium containing of Fetal Bovine Serum 10% (FBS). The half maximal inhibitory concentration (IC₅₀) was assayed by MTT method. Cell colony formation was also determined in percentage through a clonogenic assay. In this assay, a total of 1000 cells of the MCF-7 cell line were put in the wells of a 6-well plate and after 24 hours every well was treated with dosages of extract varying from 100 to 800 (). Nine days following the treatment, the percentage of colony formation was measured. Results: The MCF-7 cells exposed to different dosages of Matricaria chamomilla root extract demonstrated 50% cell death after 24, 48 and 72 hours with 19544.2 (µg/ml), 17005.1 (µg/ml), and 15605.3 (µg/ml) dosages, respectively. In addition, a drop in cell colony formation was observed. Conclusion: The results indicated that Matricaria chamomilla root extract is cytotoxic to the MCF-7 breast cancer cell line. In order to study the effects of Matricaria chamomilla root extract on cell colony formation a clonogenic assay was performed. The assay revealed a decline in colony formation. Seemingly, Matricaria chamomilla root extract can contribute to the prevention or treatment of breast cancer. Hence, more studies can be conducted to use proper dosages of active ingredients of this substance for prevention or treatment of breast cancer.

[Ali Mohammad Kamali, Mohsen Nikseresht, Hamdollah Delaviz, Mehrzad Jafari Barmak, Mahsa Servatkhah, Maryam Tajali Ardakani, Reza Mahmoudi. In Vitro Cytotoxic Activity of Matricaria Chamomilla Root Extract in Human Breast Cancer Cell Line MCF-7. Life Sci J 2014;10(5):403-406] (ISSN:1097-8135). http://www.lifesciencesite.com. 81

doi:10.7537/marslsj1105s14.81

Keywords: MTT, Matricaria chamomilla, Breast Cancer, Cytotoxic activity, Clonogenic Assay

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Genetic Analysis and Maternal Effects in Berseem Clover

Abd El-Naby, Zeinab M.^1*; Wafaa, W. M. Shafie² and M. A. El-Nahrawy¹

¹Forage Crops Research Dept., Field Crop Research Inst., ARC, Giza, Egypt

²Central Lab of Statistical Design Research, ARC, Giza, Egypt

*Corresponding author e-mail: zeina_bree@yahoo.com

Abstract: The objectives of this study were to estimate genetic parameters, six parameters, heritability, heterosis, loss of vigros and study the role of maternal effects in berseem isolated distances. Mean analysis was used to estimate magnitude of genetic variance component, the epistatic interaction and mode of inheritance in berseem clover populations. Three crosses and their reciprocals were conducted in field and greenhouse at the Agricultural Research Station at Giza during three winter seasons. Seven generations and their reciprocals were formulated by manual hybridization and subjected to generation mean analysis, plant^-1, for detecting the gene effects responsible for inheritance of the plant height, number of tillers, fresh and dry weight across parents and hybrid generations. Significant differences were computed among generations viz, P1, P2, F1, F2, F₃, BC1 (P1xF1) and BC2 (P2xF1) for the most of the studied traits in the three crosses and their reciprocals. The contributions of epitasis to the additive, dominance and interaction genetic variances were specified. Duplicate epistasis (that cause lower heteroses value) was prevailing for all studied traits in the three crosses and their reciprocals. Epistasis made substantial contributions to each of these variance components. Low values of (h²_n) in crosses of Miskawi male parent x Fahl female parent were observed for all traits except Giza-6 x Fahl in plant height mean (0.57). ((h²_b) was highly significant for multi-cut berseem cultivars as female parent in crosses with Fahl for Hatour with respect to plant height and fresh weight (0.90 and 0.84, respectively) and for Giza-6 with respect to average number of tillers (0.84). All crosses (Miskawi as female x Fahl as male) and traits showed highly significant (H_Bp). Also reciprocals recorded the same performance for heterosis across all traits except for (Giza-6 and Hatour) with respect to plant height and for Giza-6 fresh weight. Total fresh and dry yield recorded highly depression of Giza as female parent x Fahl (68.98 and 69.18%, respectively), while Hatour as female parent x Fahl had the best performance without losses in vigor's (-10.34 and -9.36%), respectively. The (CVG) values were close to (CVP) values, suggested low effects of environments and high genetic expression for all studied traits. Maternal genetic effects influenced traits throughout fresh and dry yield, including high significant direct and maternal additive genetic correlations within and between traits through cross generations. The force of maternal effects in berseem cultivars sustains the harmonious structure of population gene pool within each cultivar, enabling us to reduce isolation distance of foundation and breeder seed propagation.

[Zeinab M. Abd El-Naby; Wafaa, W. M. Shafie and M. A. El-Nahrawy. Genetic Analysis and Maternal Effects In Berseem Clover. Life Sci. J 2014; 11(5s):407-418] (ISSN: 1097-8135). http://www.lifesciencesite.com. 82

doi:10.7537/marslsj1105s14.82

Keywords: Berseem clover, Crosses, Genetic parameters, Epistasis, Maternal effects.

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Interleukin-16 expression in The Immunopathogenesis of Rheumatoid Arthritis

Elsayed A. Gouda¹, Alaa Abduldaim¹, Ahmed S. Elharoun², Taher M. Farid³, Hatim A. El-Baz³, Mahmoud Bazeed⁴

¹Microbiology and ⁴Internal Medicine Departments, Faculty of Medicine for Boys, AL-Azhar University.Egypt.

² Microbiology Department – Faculty of Medicene – North Jeddah Bransh, King Abdulaziz University, KSA.

³ Clinical Biochemistry Department – Faculty of Medicene – North Jeddah Bransh, King Abdulaziz University, KSA.

aelharoun@hotmail.com

Abstract: Rheumatoid Arthritis is a chronic inflammatory disease characterized by hyperplasia of the synovium and excessive cellular infiltration, which leads to progressive joint destruction. We analyzed, interleukin 16 (IL16), in relation to disease activity to characterize its biologic function in RA. Secreted IL-16 was measured by enzyme immunoassay in sera from 30 RA patients and 30 healthy controls. And also, in synovial fluid (SF) from 16 RA patients and 15 patients with non- RA synovitis as controls. IL-16 expression in peripheral mononuclear cells (PBMC) was characterized by flow cytometric analysis after intracellular cytokine staining for IL-16. In synovial tissue specimens, both were done:- immunohistochemistry for localization of IL-16, and histopathology, in which the tissue scored semiquantitatively for synovial hyperplasia and cellular infiltration. IL-16 was detected at significantly higher levels in sera and sf of RA patients in comparison to HC and non-RA synovitis (P < 0.001 and P < 0.0001 respectively). Also, IL-16 was detected significantly higher in SF in comparison to sera in RA patients (P < 0.001). Flow cytometry of PBMC showed that a great proportion of both CD4+ and CD8+ cells expressed IL-16 protein. Also, immunohistochemistry revealed more CD4+ and less frequency of CD8+ cells in synovial infiltration. A significant correlation between IL-16 expression and local inflammatory activity could not be established (P > 0.21) by microscopic analysis of the synovial cells infiltrate. In addition, no significant association was observed between serum, sf, and synovial tissue expression of IL -16 and clinical disease activity in RA (P > 0. 61, P > 0.51, and P > 0. 42 respectively). This indicated that, IL-16 played a regulatory rather than a proinflammatory role in the immunopathogenesis of RA.

[Elsayed A. Gouda, Alaa Abduldaim, Ahmed S. Elharoun, Taher M. Farid, Hatim A. El-Baz, Mahmoud Bazeed. Interleukin-16 expression in The Immunopathogenesis of Rheumatoid Arthritis. Life Sci J 2014; 11(5s):419-425] (ISSN: 1097-8135). http://www.lifesciencesite.com. 83

doi:10.7537/marslsj1105s14.83

Key words: Interleukin, Immunopathogenesis, Rheumatoid, Arthritis

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